Click here to switch to the map view.

The map label for this gene is psmA [H]

Identifier: 156937247

GI number: 156937247

Start: 399955

End: 400674

Strand: Reverse

Name: psmA [H]

Synonym: Igni_0453

Alternate gene names: 156937247

Gene position: 400674-399955 (Counterclockwise)

Preceding gene: 156937248

Following gene: 156937243

Centisome position: 30.88

GC content: 58.06

Gene sequence:

>720_bases
TTGGCGTTCGGCCTGGCCTCCCAGTTAGGTTACGACAGAGCGATAACCGTGTTCTCGCCCGAGGGCAAGCTCTACCAAGT
GGAGTACGCCTTCGAGGCCGTCAAGAGGGGCTGGAGCACCATAGGCGCTAAGTGTAAGGAGGGCGTCGTCGTAGCTGCCT
CCAAGAAGAAGGTGCAGACTCTGGTGGACTTCGACAAGCTTGAGAAGATACACTTCATCGACGATCACATAGTTACCAGC
TTCGCCGGCTTGGCCGCCGACGGGAGGGTGTTGGTGGACGTGGCCAGGAGGGCGGCCCTCAACTACCGCTTCCTCTACGA
CGAGCCCGCCCCGGTGGAGTACGTCACCAAGGCAGTCAGCGACCTGAAGCAAGTGTACACCCAGCACGGGGGAGTGAGGC
CCTTCGGGGTTTCCTTGATAATAGCCGGCGTGGACGACGAGCCCCAAGTGTTTATGACGGAGCCCTCGGGACAGTACATG
AGCTACAAGGCGGTGGCCATAGGCCAGAACCACCACATCCTCATGGAATTCTTGGAAGCTAACTATAAGTACGATCTGAG
CTTGGACGAGTTGGTAAAACTGGTGCTCAAGGCGTTCCTACAAGTGTCGGAGAGCGAGAAGGACCCGGAGCTTTACGAAG
TTGCAGTGGTCCCGGTGGACACCAAGACCGCGAGGAAGCTCACCGTGGAGGAGGTAGCAAAACACCTAGAGGAGCTCTGA

Upstream 100 bases:

>100_bases
CAAGTTAACTTCCGACACGGGCAGCGAGGAGTTCTTGAAGAAGCTGCACTCGTGATAATTTATACTCGTTCCCCCGCGTC
CCGTTTTTGGGTAACGAGCG

Downstream 100 bases:

>100_bases
AGTCTTAGCATCCAGCCACTTCTTTATCCATTTGACCACCTCCCTCAAGTTCCTCGCGTTGTCGAACCTCTCCAAAGCCT
CCTCCGCCTCCCTCTCGCTC

Product: proteasome subunit alpha

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PsmA [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAFGLASQLGYDRAITVFSPEGKLYQVEYAFEAVKRGWSTIGAKCKEGVVVAASKKKVQTLVDFDKLEKIHFIDDHIVTS
FAGLAADGRVLVDVARRAALNYRFLYDEPAPVEYVTKAVSDLKQVYTQHGGVRPFGVSLIIAGVDDEPQVFMTEPSGQYM
SYKAVAIGQNHHILMEFLEANYKYDLSLDELVKLVLKAFLQVSESEKDPELYEVAVVPVDTKTARKLTVEEVAKHLEEL

Sequences:

>Translated_239_residues
MAFGLASQLGYDRAITVFSPEGKLYQVEYAFEAVKRGWSTIGAKCKEGVVVAASKKKVQTLVDFDKLEKIHFIDDHIVTS
FAGLAADGRVLVDVARRAALNYRFLYDEPAPVEYVTKAVSDLKQVYTQHGGVRPFGVSLIIAGVDDEPQVFMTEPSGQYM
SYKAVAIGQNHHILMEFLEANYKYDLSLDELVKLVLKAFLQVSESEKDPELYEVAVVPVDTKTARKLTVEEVAKHLEEL
>Mature_238_residues
AFGLASQLGYDRAITVFSPEGKLYQVEYAFEAVKRGWSTIGAKCKEGVVVAASKKKVQTLVDFDKLEKIHFIDDHIVTSF
AGLAADGRVLVDVARRAALNYRFLYDEPAPVEYVTKAVSDLKQVYTQHGGVRPFGVSLIIAGVDDEPQVFMTEPSGQYMS
YKAVAIGQNHHILMEFLEANYKYDLSLDELVKLVLKAFLQVSESEKDPELYEVAVVPVDTKTARKLTVEEVAKHLEEL

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family [H]

Homologues:

Organism=Homo sapiens, GI4506189, Length=232, Percent_Identity=42.6724137931034, Blast_Score=180, Evalue=8e-46,
Organism=Homo sapiens, GI68303563, Length=199, Percent_Identity=46.2311557788945, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI68303561, Length=205, Percent_Identity=44.8780487804878, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI4506181, Length=231, Percent_Identity=38.0952380952381, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI23110944, Length=236, Percent_Identity=35.5932203389831, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI4506179, Length=209, Percent_Identity=38.755980861244, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI23110935, Length=209, Percent_Identity=38.755980861244, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI23110942, Length=213, Percent_Identity=39.4366197183099, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI156713442, Length=214, Percent_Identity=37.3831775700935, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI4506185, Length=214, Percent_Identity=37.3831775700935, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI68303565, Length=199, Percent_Identity=39.1959798994975, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI4506183, Length=201, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=7e-28,
Organism=Homo sapiens, GI23110939, Length=199, Percent_Identity=33.6683417085427, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI221316716, Length=109, Percent_Identity=42.2018348623853, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI156713444, Length=145, Percent_Identity=35.8620689655172, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508491, Length=196, Percent_Identity=45.4081632653061, Blast_Score=182, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25143215, Length=227, Percent_Identity=40.0881057268723, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17508493, Length=219, Percent_Identity=40.6392694063927, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17562790, Length=235, Percent_Identity=37.4468085106383, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17562788, Length=242, Percent_Identity=30.9917355371901, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17562792, Length=197, Percent_Identity=34.5177664974619, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71998965, Length=201, Percent_Identity=30.3482587064677, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324535, Length=237, Percent_Identity=42.1940928270042, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6321574, Length=198, Percent_Identity=42.9292929292929, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321692, Length=215, Percent_Identity=40, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323547, Length=246, Percent_Identity=35.3658536585366, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324938, Length=208, Percent_Identity=39.9038461538462, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321427, Length=176, Percent_Identity=36.3636363636364, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323974, Length=220, Percent_Identity=34.0909090909091, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17933602, Length=211, Percent_Identity=40.7582938388626, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI19922898, Length=198, Percent_Identity=37.8787878787879, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21356137, Length=198, Percent_Identity=37.3737373737374, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI17737927, Length=208, Percent_Identity=38.4615384615385, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24654391, Length=237, Percent_Identity=35.4430379746835, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24654389, Length=237, Percent_Identity=35.4430379746835, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17136420, Length=222, Percent_Identity=37.8378378378378, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360341, Length=237, Percent_Identity=33.7552742616034, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24586406, Length=237, Percent_Identity=33.7552742616034, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24586400, Length=237, Percent_Identity=33.7552742616034, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24586402, Length=237, Percent_Identity=33.7552742616034, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI17737405, Length=212, Percent_Identity=38.6792452830189, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24651571, Length=172, Percent_Identity=39.5348837209302, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19921232, Length=193, Percent_Identity=36.7875647668394, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24652204, Length=211, Percent_Identity=34.1232227488152, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019982
- InterPro:   IPR000426
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome; PF10584 Proteasome_A_N [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 26654; Mature: 26523

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00388 PROTEASOME_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGLASQLGYDRAITVFSPEGKLYQVEYAFEAVKRGWSTIGAKCKEGVVVAASKKKVQT
CCCCCHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCHHHCCEEEEECHHHHHH
LVDFDKLEKIHFIDDHIVTSFAGLAADGRVLVDVARRAALNYRFLYDEPAPVEYVTKAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHH
DLKQVYTQHGGVRPFGVSLIIAGVDDEPQVFMTEPSGQYMSYKAVAIGQNHHILMEFLEA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEECCCCCEEEEEEEEECCCCHHHHHHHHC
NYKYDLSLDELVKLVLKAFLQVSESEKDPELYEVAVVPVDTKTARKLTVEEVAKHLEEL
CCEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
AFGLASQLGYDRAITVFSPEGKLYQVEYAFEAVKRGWSTIGAKCKEGVVVAASKKKVQT
CCCCHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCHHHCCEEEEECHHHHHH
LVDFDKLEKIHFIDDHIVTSFAGLAADGRVLVDVARRAALNYRFLYDEPAPVEYVTKAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHH
DLKQVYTQHGGVRPFGVSLIIAGVDDEPQVFMTEPSGQYMSYKAVAIGQNHHILMEFLEA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEECCCCCEEEEEEEEECCCCHHHHHHHHC
NYKYDLSLDELVKLVLKAFLQVSESEKDPELYEVAVVPVDTKTARKLTVEEVAKHLEEL
CCEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA