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The map label for this gene is rpiA [H]

Identifier: 156937222

GI number: 156937222

Start: 379924

End: 380589

Strand: Reverse

Name: rpiA [H]

Synonym: Igni_0428

Alternate gene names: 156937222

Gene position: 380589-379924 (Counterclockwise)

Preceding gene: 156937223

Following gene: 156937221

Centisome position: 29.33

GC content: 63.51

Gene sequence:

>666_bases
TTGAGCGGGAAGGAGGCGGTCGCCAGGAGGGCGGCGGAGCTGGTCGCCTCGGAGGCCCCGGAGGTGTTGGGCGTAGGCTC
CGGGACTACCGTGAGGCTGTTCATAAAGTACCTCAAGGAGTTCGGCTTCTCCGGCTTGACGGTCCCGACCAGCTACGACA
CGGCCTTGGAGCTCAAGAAGCACGGGCTTAAGGTTTTGGACTTAATGAGCGTGGATGAGGTGGAGCTCAGCGTCGACGGG
GCGGACGAGGTCTTCACAATGAACGGCTCTCTGTACGCCGTGAAGGGCGGCGGGGCGGCGATGCTCAGGGAGAAGGTCCT
CGCTTACATCTCTAGGAAGAGGATCTACATCGTGGACGAGGGGAAGGTGTCGGGCTCCCCGTGCTCCCGAGGGGTCCCGG
TCCCGGCGGAGGTGGTGCCCAGCTCCTTGCCGGCGGTGGCGAGGGGGCTGAAGCTCTTGGGCGTGGGGTGGAAGTTGAGG
GAGGCGAAGGGGAAGCTCGGCCCGGTGGTCACGGACAACGGCAACTTAGTTATAGACATGGACTGCAAGAGCTCAATTAA
CGTGATAGAAAAGGTGGAGGCCTTGCCGGGGGTGGCGGTCACCGGGCTTTTCGGCCCTGACCTCATCGACAAGGTCGTGG
TCGGCGAGAGGGGGGAGCTCCCTTGA

Upstream 100 bases:

>100_bases
AGAAGAGCCACATCTGCCCGCAGTTCTCGCACCTCAAGTACCAGCTCGTCAAGCCCGCTCGCCGGAAAAGCGGGGGAGGG
GGAGTAATTTAGGCGGGAGC

Downstream 100 bases:

>100_bases
GGCCGAGGGCTTCAAATCTGAAGTCCCTCTGTCCTAAGGAGAAGACCAAGGTAGGGATACCGGTGATCAAGGTGGTCAAC
CGCGACCTCCCCGAGGTAAC

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSGKEAVARRAAELVASEAPEVLGVGSGTTVRLFIKYLKEFGFSGLTVPTSYDTALELKKHGLKVLDLMSVDEVELSVDG
ADEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDEGKVSGSPCSRGVPVPAEVVPSSLPAVARGLKLLGVGWKLR
EAKGKLGPVVTDNGNLVIDMDCKSSINVIEKVEALPGVAVTGLFGPDLIDKVVVGERGELP

Sequences:

>Translated_221_residues
MSGKEAVARRAAELVASEAPEVLGVGSGTTVRLFIKYLKEFGFSGLTVPTSYDTALELKKHGLKVLDLMSVDEVELSVDG
ADEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDEGKVSGSPCSRGVPVPAEVVPSSLPAVARGLKLLGVGWKLR
EAKGKLGPVVTDNGNLVIDMDCKSSINVIEKVEALPGVAVTGLFGPDLIDKVVVGERGELP
>Mature_220_residues
SGKEAVARRAAELVASEAPEVLGVGSGTTVRLFIKYLKEFGFSGLTVPTSYDTALELKKHGLKVLDLMSVDEVELSVDGA
DEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDEGKVSGSPCSRGVPVPAEVVPSSLPAVARGLKLLGVGWKLRE
AKGKLGPVVTDNGNLVIDMDCKSSINVIEKVEALPGVAVTGLFGPDLIDKVVVGERGELP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=211, Percent_Identity=34.1232227488152, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI1789280, Length=219, Percent_Identity=36.5296803652968, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551758, Length=195, Percent_Identity=36.4102564102564, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=223, Percent_Identity=30.4932735426009, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281364072, Length=205, Percent_Identity=35.1219512195122, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23254; Mature: 23123

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKEAVARRAAELVASEAPEVLGVGSGTTVRLFIKYLKEFGFSGLTVPTSYDTALELKK
CCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HGLKVLDLMSVDEVELSVDGADEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDE
CCCEEEEECCCCCEEEEECCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEC
GKVSGSPCSRGVPVPAEVVPSSLPAVARGLKLLGVGWKLREAKGKLGPVVTDNGNLVIDM
CCCCCCCCCCCCCCCHHHCCCCCHHHHHCCEEECCCEEEECCCCCCCCEEECCCCEEEEE
DCKSSINVIEKVEALPGVAVTGLFGPDLIDKVVVGERGELP
CCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SGKEAVARRAAELVASEAPEVLGVGSGTTVRLFIKYLKEFGFSGLTVPTSYDTALELKK
CCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HGLKVLDLMSVDEVELSVDGADEVFTMNGSLYAVKGGGAAMLREKVLAYISRKRIYIVDE
CCCEEEEECCCCCEEEEECCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEC
GKVSGSPCSRGVPVPAEVVPSSLPAVARGLKLLGVGWKLREAKGKLGPVVTDNGNLVIDM
CCCCCCCCCCCCCCCHHHCCCCCHHHHHCCEEECCCEEEECCCCCCCCEEECCCCEEEEE
DCKSSINVIEKVEALPGVAVTGLFGPDLIDKVVVGERGELP
CCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]