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The map label for this gene is hypB [H]

Identifier: 156937149

GI number: 156937149

Start: 311280

End: 311921

Strand: Reverse

Name: hypB [H]

Synonym: Igni_0355

Alternate gene names: 156937149

Gene position: 311921-311280 (Counterclockwise)

Preceding gene: 156937150

Following gene: 156937148

Centisome position: 24.04

GC content: 57.32

Gene sequence:

>642_bases
GTGCCCCGCCTGGTCACCATAAAGGTGGACGTCAACCAGAAGTACTTGGACAAAGCGGCCGAGCTGAGGAGGCTGTACGA
CAAATACGGCGTCAAGGTGTTCGAGTTCTTGGGTAGCCCGGGCTCCGGGAAGACCGCGCTCATAGAGGCGCTGGTCGACA
GGTTGAAGGACAAGTACGAGATCTTGTACTTGGGGGGCGACGTGGCCTCAACCCTAGACGCCGAGAGGGTCTCGAGGCAC
GGGGTGGAGGGCGTCGAGATAAACACGGGTGGTATTTGCCACTTGGAGCCAGACCACATCTTTGAGGCTCTCAAGGACGT
CGACCTCAGCAAGTACGATATCATGTTTATAGAGAACGTGGGCAACTTGATATGTCCTTTCAACTTCCCCTTGGGCGCTC
ATAAGAGGGTCATGGTAGTCTCCGTAGCGGAGGGGGAGGACAAGTTCGTGAAGCACCCGATGAGCACGAAGAGGTCAGAC
GTAATAGTGATATCTAAGGTCGACATGGCTGGTCCCTTGGGAGTGGACGTGGAGAAGATGGTGAACGACGCCAAGTCGCT
CAACCCCCGCGCGCCGGTAGTGTTGGTCTCGGTCAAGACCGGCGAGGGCTTAGAGGAGCTCCAGAGGGCCTTGGGCCTTT
GA

Upstream 100 bases:

>100_bases
AGATCAAGCGCCCCTCCGGGAGACGCCGGCGCCCAGTTATTTAGTTTGACGTACGTTACACACAATAATCCCTAATCCGT
GCACAAGGCGGGTAAGCGCA

Downstream 100 bases:

>100_bases
TCGTCCCGGAGAGGCCCTTGCTCAAGCTCGAGGCCTTCCACTGCACCGTAAAGGAAAAGGTAAACAGGTTTGTGGTGAGG
GCCTCCGTGGGGGAGGAGGA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPRLVTIKVDVNQKYLDKAAELRRLYDKYGVKVFEFLGSPGSGKTALIEALVDRLKDKYEILYLGGDVASTLDAERVSRH
GVEGVEINTGGICHLEPDHIFEALKDVDLSKYDIMFIENVGNLICPFNFPLGAHKRVMVVSVAEGEDKFVKHPMSTKRSD
VIVISKVDMAGPLGVDVEKMVNDAKSLNPRAPVVLVSVKTGEGLEELQRALGL

Sequences:

>Translated_213_residues
MPRLVTIKVDVNQKYLDKAAELRRLYDKYGVKVFEFLGSPGSGKTALIEALVDRLKDKYEILYLGGDVASTLDAERVSRH
GVEGVEINTGGICHLEPDHIFEALKDVDLSKYDIMFIENVGNLICPFNFPLGAHKRVMVVSVAEGEDKFVKHPMSTKRSD
VIVISKVDMAGPLGVDVEKMVNDAKSLNPRAPVVLVSVKTGEGLEELQRALGL
>Mature_212_residues
PRLVTIKVDVNQKYLDKAAELRRLYDKYGVKVFEFLGSPGSGKTALIEALVDRLKDKYEILYLGGDVASTLDAERVSRHG
VEGVEINTGGICHLEPDHIFEALKDVDLSKYDIMFIENVGNLICPFNFPLGAHKRVMVVSVAEGEDKFVKHPMSTKRSDV
IVISKVDMAGPLGVDVEKMVNDAKSLNPRAPVVLVSVKTGEGLEELQRALGL

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=205, Percent_Identity=36.5853658536585, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23452; Mature: 23320

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLVTIKVDVNQKYLDKAAELRRLYDKYGVKVFEFLGSPGSGKTALIEALVDRLKDKYE
CCEEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
ILYLGGDVASTLDAERVSRHGVEGVEINTGGICHLEPDHIFEALKDVDLSKYDIMFIENV
EEEECCCHHHHHHHHHHHHCCCCCEEECCCCEEEECHHHHHHHHHHCCCCCEEEEEEECC
GNLICPFNFPLGAHKRVMVVSVAEGEDKFVKHPMSTKRSDVIVISKVDMAGPLGVDVEKM
CCEEECCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHH
VNDAKSLNPRAPVVLVSVKTGEGLEELQRALGL
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
PRLVTIKVDVNQKYLDKAAELRRLYDKYGVKVFEFLGSPGSGKTALIEALVDRLKDKYE
CEEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
ILYLGGDVASTLDAERVSRHGVEGVEINTGGICHLEPDHIFEALKDVDLSKYDIMFIENV
EEEECCCHHHHHHHHHHHHCCCCCEEECCCCEEEECHHHHHHHHHHCCCCCEEEEEEECC
GNLICPFNFPLGAHKRVMVVSVAEGEDKFVKHPMSTKRSDVIVISKVDMAGPLGVDVEKM
CCEEECCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHH
VNDAKSLNPRAPVVLVSVKTGEGLEELQRALGL
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]