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The map label for this gene is pheA [H]

Identifier: 156937101

GI number: 156937101

Start: 262175

End: 263110

Strand: Reverse

Name: pheA [H]

Synonym: Igni_0307

Alternate gene names: 156937101

Gene position: 263110-262175 (Counterclockwise)

Preceding gene: 156937104

Following gene: 156937099

Centisome position: 20.28

GC content: 57.69

Gene sequence:

>936_bases
TTGGACGTAGTGGAAGAGCTCTTGAAGTTAGCGGAGAGGGCCGCGAGGGAGAGGCCTACGAGGCTGCCCTCCGGCACGTG
GCCGGAGGAGCTGAAGCCGGTAATAGAGTGGCTCCGCTCGCTCAGCCCAATGAAGGTCAAGGTGGCCTACTTGGGGCCCC
CGGGGAGCTACACCCACGAGGCGGCGTCCTTAGTCTTCCCCAAGGAGGAGCTCGTGTCGAAGGGCAGCATACCGGAGGTG
TTCGAGTCAGTGGAGAAGGGGGAGGCGGACTTCGGGGTAGTACCAATAGCGAACAGGCTGGAGGGGCCCGTCAACGAGAC
CATAGACGCGTTCTTGCAGTCCCACGTAAAGGTTTACTACGACGTGGAGATACCGATAAGGATAATGTTGGCCTCGGGGA
CTGTGAAGGACGTAAAGGAAATTAAAAGGGTCTATGGACACCCTATGATATTTAAGCAAGCTACCAAACTTTTGAAGGAG
TTGGGGGTAGAGCAAGTACCTACCAGCAGCACGTCGGAAGCCGCTAGGATAGCGGCCCAAGAGCCCGGGGCGGCGGCGCT
TTGTTCTCCCAAGGCGGTGGAGATGTACAAGCTGAAAGTATTGAGGGCGAACGTGGAGGACAAGCCTCACAACGCCACTA
GGTTCTTCGTGATACACAAGAGGGACAACCCGGAGGGCGACAAGACGGCCTTGCTCGCCTCCGTCCCCCACAGGCCCGGG
GGACTGTTCGAGTTCCTAAAGCCATTCGCGGAGAGGGGGATCAACCTAACCATGATATACTCAAGGCCCCTCAAGGACCA
CCCGTGGAGGTACGTGTTTTACATCGAAACGGAGGGCTCCCGGGAGGCCCTCAAGGAGGTGTTGGAGGAGGCATCCAAGA
TATCCTCGTTCTTGAAGATCTTGGGAAGCTACACCAAGCTGGACCTAACTGGCTAG

Upstream 100 bases:

>100_bases
TCAGTGTTTATGAGGACTATCGCTAACGCCACCCTCGCTACCCACATCGGGGCGCGCGTCCATCTTATTAGCGTTCCTCC
AAGGGCCTCGCGGTGAATCC

Downstream 100 bases:

>100_bases
TCCAGCTCCATCAAGCGCTCCTCCAAGGCCTTCCGGGCCAACCCCCTCTTCACCCCTTCGACCACCTTGGAGGGGAGGGT
CACCTCGTCCCTCGTGTACT

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDVVEELLKLAERAARERPTRLPSGTWPEELKPVIEWLRSLSPMKVKVAYLGPPGSYTHEAASLVFPKEELVSKGSIPEV
FESVEKGEADFGVVPIANRLEGPVNETIDAFLQSHVKVYYDVEIPIRIMLASGTVKDVKEIKRVYGHPMIFKQATKLLKE
LGVEQVPTSSTSEAARIAAQEPGAAALCSPKAVEMYKLKVLRANVEDKPHNATRFFVIHKRDNPEGDKTALLASVPHRPG
GLFEFLKPFAERGINLTMIYSRPLKDHPWRYVFYIETEGSREALKEVLEEASKISSFLKILGSYTKLDLTG

Sequences:

>Translated_311_residues
MDVVEELLKLAERAARERPTRLPSGTWPEELKPVIEWLRSLSPMKVKVAYLGPPGSYTHEAASLVFPKEELVSKGSIPEV
FESVEKGEADFGVVPIANRLEGPVNETIDAFLQSHVKVYYDVEIPIRIMLASGTVKDVKEIKRVYGHPMIFKQATKLLKE
LGVEQVPTSSTSEAARIAAQEPGAAALCSPKAVEMYKLKVLRANVEDKPHNATRFFVIHKRDNPEGDKTALLASVPHRPG
GLFEFLKPFAERGINLTMIYSRPLKDHPWRYVFYIETEGSREALKEVLEEASKISSFLKILGSYTKLDLTG
>Mature_311_residues
MDVVEELLKLAERAARERPTRLPSGTWPEELKPVIEWLRSLSPMKVKVAYLGPPGSYTHEAASLVFPKEELVSKGSIPEV
FESVEKGEADFGVVPIANRLEGPVNETIDAFLQSHVKVYYDVEIPIRIMLASGTVKDVKEIKRVYGHPMIFKQATKLLKE
LGVEQVPTSSTSEAARIAAQEPGAAALCSPKAVEMYKLKVLRANVEDKPHNATRFFVIHKRDNPEGDKTALLASVPHRPG
GLFEFLKPFAERGINLTMIYSRPLKDHPWRYVFYIETEGSREALKEVLEEASKISSFLKILGSYTKLDLTG

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=283, Percent_Identity=31.4487632508834, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324013, Length=319, Percent_Identity=25.0783699059561, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 34770; Mature: 34770

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVEELLKLAERAARERPTRLPSGTWPEELKPVIEWLRSLSPMKVKVAYLGPPGSYTHE
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
AASLVFPKEELVSKGSIPEVFESVEKGEADFGVVPIANRLEGPVNETIDAFLQSHVKVYY
HHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCCEEECHHHCCCCHHHHHHHHHHHCCEEEE
DVEIPIRIMLASGTVKDVKEIKRVYGHPMIFKQATKLLKELGVEQVPTSSTSEAARIAAQ
EEECCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
EPGAAALCSPKAVEMYKLKVLRANVEDKPHNATRFFVIHKRDNPEGDKTALLASVPHRPG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCC
GLFEFLKPFAERGINLTMIYSRPLKDHPWRYVFYIETEGSREALKEVLEEASKISSFLKI
HHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LGSYTKLDLTG
HCCCCEEEECC
>Mature Secondary Structure
MDVVEELLKLAERAARERPTRLPSGTWPEELKPVIEWLRSLSPMKVKVAYLGPPGSYTHE
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHH
AASLVFPKEELVSKGSIPEVFESVEKGEADFGVVPIANRLEGPVNETIDAFLQSHVKVYY
HHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCCEEECHHHCCCCHHHHHHHHHHHCCEEEE
DVEIPIRIMLASGTVKDVKEIKRVYGHPMIFKQATKLLKELGVEQVPTSSTSEAARIAAQ
EEECCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
EPGAAALCSPKAVEMYKLKVLRANVEDKPHNATRFFVIHKRDNPEGDKTALLASVPHRPG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCC
GLFEFLKPFAERGINLTMIYSRPLKDHPWRYVFYIETEGSREALKEVLEEASKISSFLKI
HHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LGSYTKLDLTG
HCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]