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The map label for this gene is aroD

Identifier: 156937075

GI number: 156937075

Start: 241125

End: 241772

Strand: Reverse

Name: aroD

Synonym: Igni_0280

Alternate gene names: 156937075

Gene position: 241772-241125 (Counterclockwise)

Preceding gene: 156937076

Following gene: 156937074

Centisome position: 18.63

GC content: 61.42

Gene sequence:

>648_bases
GTGTACGCGGTGGCGTCCATACCGTTTACCGACTTAGGGCAAGTTAAGAAGCTTATAATTAAGTCGGCCGCCGCCGGAGC
GGACTTCGTGGAGCTCAGGTTGGACTATTGGACCCGCAAGGAGACGCCCCCGTTCTTGGAAATGATAGAGTTGGCAAGGA
ACTACGGCTTAGACGTGATAGTTACGGTCAGGGACCCGGAGGAGGGAGGGGTCTGGTCCCCTCCTTGGAGGGGGGAGGCC
TACGAGATGGCCTCGGAGGCCGGAGCGGTCTGCGACGTGGAGGTTAAGAAGTTTAAGGAACTCCCTTGCGATAGGGCGAT
CCTCTCCGTCCACTACTTCCGGAAGCCTCCCCGGGAGGGGGAGGTAAGGAAGCTCTCCCAGAGGGCACTGGAGGCGGGGG
CGTGGGCTTTTAAGGTAGCTACGGTAGTGACGGACTTTCCGTCGTACTTCTTGTTGTTCAGCGAGAGCGTGCACCCCAGG
ACGGCCTTCATGCCTATGGGCGAGGGGACGGAGGCCTTGAGGTTGGCGTCGGCTCTGCTGGGCAGCTTCTTGAACTACGG
GAGCGTGGGGGAGGCCACCGCCCCGGGCCAAGTGAGCGTCCGTCAACTGACAAAAGCCTTGAGCGCCCTTGGGGGGCGCG
GGGACTGA

Upstream 100 bases:

>100_bases
ATACTTTTTCTCTTGCTCCTCTCCGTAGAGCTCGTCGTAACCCTTGGCTATCGCAGAATAATATCGAGCGCTGTCCCTAA
CCGCCTCCCAGGGGTCCCCC

Downstream 100 bases:

>100_bases
CCGTGAAGGGGCCTTCGTCTGCCGTCTTGATCTTGCTCTTCTTAAGCTTCATAGGAATAGACGTAGCTCACGTCATTGGA
GTAATAAAGACGTTCCCCTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MYAVASIPFTDLGQVKKLIIKSAAAGADFVELRLDYWTRKETPPFLEMIELARNYGLDVIVTVRDPEEGGVWSPPWRGEA
YEMASEAGAVCDVEVKKFKELPCDRAILSVHYFRKPPREGEVRKLSQRALEAGAWAFKVATVVTDFPSYFLLFSESVHPR
TAFMPMGEGTEALRLASALLGSFLNYGSVGEATAPGQVSVRQLTKALSALGGRGD

Sequences:

>Translated_215_residues
MYAVASIPFTDLGQVKKLIIKSAAAGADFVELRLDYWTRKETPPFLEMIELARNYGLDVIVTVRDPEEGGVWSPPWRGEA
YEMASEAGAVCDVEVKKFKELPCDRAILSVHYFRKPPREGEVRKLSQRALEAGAWAFKVATVVTDFPSYFLLFSESVHPR
TAFMPMGEGTEALRLASALLGSFLNYGSVGEATAPGQVSVRQLTKALSALGGRGD
>Mature_215_residues
MYAVASIPFTDLGQVKKLIIKSAAAGADFVELRLDYWTRKETPPFLEMIELARNYGLDVIVTVRDPEEGGVWSPPWRGEA
YEMASEAGAVCDVEVKKFKELPCDRAILSVHYFRKPPREGEVRKLSQRALEAGAWAFKVATVVTDFPSYFLLFSESVHPR
TAFMPMGEGTEALRLASALLGSFLNYGSVGEATAPGQVSVRQLTKALSALGGRGD

Specific function: Unknown

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_IGNH4 (A8A962)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001434871.1
- ProteinModelPortal:   A8A962
- SMR:   A8A962
- STRING:   A8A962
- GeneID:   5563026
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0280
- eggNOG:   arNOG10792
- HOGENOM:   HBG553407
- OMA:   ILYDVEA
- BioCyc:   IHOS453591:IGNI_0280-MONOMER
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 23593; Mature: 23593

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 111-111 ACT_SITE 138-138

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAVASIPFTDLGQVKKLIIKSAAAGADFVELRLDYWTRKETPPFLEMIELARNYGLDVI
CCEECCCCCCCHHHHHHHHHHHHCCCCHHEEEEEHHHCCCCCCHHHHHHHHHHHCCCEEE
VTVRDPEEGGVWSPPWRGEAYEMASEAGAVCDVEVKKFKELPCDRAILSVHYFRKPPREG
EEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EVRKLSQRALEAGAWAFKVATVVTDFPSYFLLFSESVHPRTAFMPMGEGTEALRLASALL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHH
GSFLNYGSVGEATAPGQVSVRQLTKALSALGGRGD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYAVASIPFTDLGQVKKLIIKSAAAGADFVELRLDYWTRKETPPFLEMIELARNYGLDVI
CCEECCCCCCCHHHHHHHHHHHHCCCCHHEEEEEHHHCCCCCCHHHHHHHHHHHCCCEEE
VTVRDPEEGGVWSPPWRGEAYEMASEAGAVCDVEVKKFKELPCDRAILSVHYFRKPPREG
EEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EVRKLSQRALEAGAWAFKVATVVTDFPSYFLLFSESVHPRTAFMPMGEGTEALRLASALL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHH
GSFLNYGSVGEATAPGQVSVRQLTKALSALGGRGD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA