Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 156937055

GI number: 156937055

Start: 224474

End: 225136

Strand: Reverse

Name: moaE [H]

Synonym: Igni_0260

Alternate gene names: 156937055

Gene position: 225136-224474 (Counterclockwise)

Preceding gene: 156937058

Following gene: 156937054

Centisome position: 17.35

GC content: 57.62

Gene sequence:

>663_bases
TTGAAGGTCAAGTTGAAGTTGTACGCTATGTACAAGGACGCGCTCGGTGAGGCCGCGGAGCTCGAGTTGCCGGAGGGCTC
TAAGGTGGCCGACCTCAAGAGGAAGGTTCTCGAGCTGTTGCCGGAGGGCTACCCAGAGCCCGTGGTCTTGAAGGACGGCA
GGTTCGCCGAGGACGAAGAGCCCTTAACGGAGGGGGAGTACGAGCTGGTGCCCCCCGCCGCCGGCGGAGGGGGGAGGGTG
GTGCTCACCGAAGAGGAGGACTGGAGCTTGGACGGCTTGGTGGAGGAGTTGGGCGACCCCGAGTCGGGTGCCACGGTAAT
CTTCGTTGGGACGGTAAAATCTAAAGGATCTAAAGTATTAGAGCTAATATACGAAGCTCATCCGAGCGTGAAGGAGTTTA
TGGAAAAGATAGTGGAGGAGGAACTGAAGAAGTGGGGGGCCTTAGACGCGAGGGTGGTGCAGTTCTTAGGGCCCCGTAAG
GTGGGACAAAAAACCTTGATAATAGCAGTTAGCGGAAAGGATAGGGAGAGCGCGTTCAAAGCCGCTAGGGAGATCTTAGA
GAGGTTGAAGCACGAGCCCCCGATATGGAAGAGGGAAGTGAGGACCGACGGCGAGTACTGGATAACCGGGGAGGGCGAGC
TGAGGCGCTCCCCTAAGTATTAA

Upstream 100 bases:

>100_bases
CGGAGCCCCTACCAGTTACCCGTTCCATTTATATAAGCTTGGGCGCGGACGACCGCTCCCCTCAAATCCCGCGGGGGCGT
AACGAAGGCGGAGGCGCGAG

Downstream 100 bases:

>100_bases
CCCCTACGTCCCTAAGCTCTGGGGTCCCGAGTGGAAGCCGTAGAGCTAGAGCGGGGACTTTACGCCACCCCTCAAGGGGC
CTTGCTGTACAAGGGCTATG

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKVKLKLYAMYKDALGEAAELELPEGSKVADLKRKVLELLPEGYPEPVVLKDGRFAEDEEPLTEGEYELVPPAAGGGGRV
VLTEEEDWSLDGLVEELGDPESGATVIFVGTVKSKGSKVLELIYEAHPSVKEFMEKIVEEELKKWGALDARVVQFLGPRK
VGQKTLIIAVSGKDRESAFKAAREILERLKHEPPIWKREVRTDGEYWITGEGELRRSPKY

Sequences:

>Translated_220_residues
MKVKLKLYAMYKDALGEAAELELPEGSKVADLKRKVLELLPEGYPEPVVLKDGRFAEDEEPLTEGEYELVPPAAGGGGRV
VLTEEEDWSLDGLVEELGDPESGATVIFVGTVKSKGSKVLELIYEAHPSVKEFMEKIVEEELKKWGALDARVVQFLGPRK
VGQKTLIIAVSGKDRESAFKAAREILERLKHEPPIWKREVRTDGEYWITGEGELRRSPKY
>Mature_220_residues
MKVKLKLYAMYKDALGEAAELELPEGSKVADLKRKVLELLPEGYPEPVVLKDGRFAEDEEPLTEGEYELVPPAAGGGGRV
VLTEEEDWSLDGLVEELGDPESGATVIFVGTVKSKGSKVLELIYEAHPSVKEFMEKIVEEELKKWGALDARVVQFLGPRK
VGQKTLIIAVSGKDRESAFKAAREILERLKHEPPIWKREVRTDGEYWITGEGELRRSPKY

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=131, Percent_Identity=32.0610687022901, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787003, Length=111, Percent_Identity=32.4324324324324, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 24606; Mature: 24606

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKLKLYAMYKDALGEAAELELPEGSKVADLKRKVLELLPEGYPEPVVLKDGRFAEDEE
CEEEEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
PLTEGEYELVPPAAGGGGRVVLTEEEDWSLDGLVEELGDPESGATVIFVGTVKSKGSKVL
CCCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
ELIYEAHPSVKEFMEKIVEEELKKWGALDARVVQFLGPRKVGQKTLIIAVSGKDRESAFK
HHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
AAREILERLKHEPPIWKREVRTDGEYWITGEGELRRSPKY
HHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVKLKLYAMYKDALGEAAELELPEGSKVADLKRKVLELLPEGYPEPVVLKDGRFAEDEE
CEEEEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
PLTEGEYELVPPAAGGGGRVVLTEEEDWSLDGLVEELGDPESGATVIFVGTVKSKGSKVL
CCCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
ELIYEAHPSVKEFMEKIVEEELKKWGALDARVVQFLGPRKVGQKTLIIAVSGKDRESAFK
HHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
AAREILERLKHEPPIWKREVRTDGEYWITGEGELRRSPKY
HHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]