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The map label for this gene is dcd

Identifier: 156937019

GI number: 156937019

Start: 198065

End: 198607

Strand: Reverse

Name: dcd

Synonym: Igni_0224

Alternate gene names: 156937019

Gene position: 198607-198065 (Counterclockwise)

Preceding gene: 156937021

Following gene: 156937017

Centisome position: 15.31

GC content: 50.83

Gene sequence:

>543_bases
TTGATTCTCTCCGACGGCGGCATAAAATCCTATTTAAGGAGGGGACTAATGAAGATAGAACCCTTCGACGAGAACCAAGT
GCGCGAGAACGGGGTAGACTTGACCATTGGCCACCAATATGCGAGATTCAAAAATACGGAAGACGTATTGGACGTCACCA
AGGAGGAAGACTTGAGCAAGTACTACGAACTGGGCTTTATGGACGACGAAGGGATAGTGATAAAGCCTTACGAACACGTA
CTTCTCCACACGAGAGAGTACATAGAAATGCCGGCCGACTTAGTAGGCTTGGTAAATCTAAAGAGCTCCTTCGCGCGCTT
GGGCCTTTACATACCGCCGACGGTTGTGGACGCGGGCTTCAAGGGCGAAATAGTGATTGAAATAATCGGGAGCTCCTTCC
CCGTGAGGGTGAGGCCGGGGGTGCCGTTCATTCACTTGGTCTTCCTCAGGACAGACTCTCCCGTGTTACGGGACTATAGC
GTTAGAGGCCATTATCAAGGACAAAGGGGGATAAGGTTGCCCAAGCTGCCCATAAAGCTCTGA

Upstream 100 bases:

>100_bases
TTTTGAAAACCCTTCAGGCTCTTCTCATTCGGCGTTTATTAGTGACGCCCTGCAACGGCGTTATTACCCGAGTTTCCTCT
AGATCTGCAACGGGACGTAC

Downstream 100 bases:

>100_bases
CTACGCCTTAAGCCACCAAGGCTTGCCTCTTCTCGTAAACGAGCTCCCACGAGCGGACGTCCTTCATCTCCTTCCCGACT
ACCTTGGGCGTGGCCTCCTC

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MILSDGGIKSYLRRGLMKIEPFDENQVRENGVDLTIGHQYARFKNTEDVLDVTKEEDLSKYYELGFMDDEGIVIKPYEHV
LLHTREYIEMPADLVGLVNLKSSFARLGLYIPPTVVDAGFKGEIVIEIIGSSFPVRVRPGVPFIHLVFLRTDSPVLRDYS
VRGHYQGQRGIRLPKLPIKL

Sequences:

>Translated_180_residues
MILSDGGIKSYLRRGLMKIEPFDENQVRENGVDLTIGHQYARFKNTEDVLDVTKEEDLSKYYELGFMDDEGIVIKPYEHV
LLHTREYIEMPADLVGLVNLKSSFARLGLYIPPTVVDAGFKGEIVIEIIGSSFPVRVRPGVPFIHLVFLRTDSPVLRDYS
VRGHYQGQRGIRLPKLPIKL
>Mature_180_residues
MILSDGGIKSYLRRGLMKIEPFDENQVRENGVDLTIGHQYARFKNTEDVLDVTKEEDLSKYYELGFMDDEGIVIKPYEHV
LLHTREYIEMPADLVGLVNLKSSFARLGLYIPPTVVDAGFKGEIVIEIIGSSFPVRVRPGVPFIHLVFLRTDSPVLRDYS
VRGHYQGQRGIRLPKLPIKL

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=185, Percent_Identity=32.4324324324324, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_IGNH4 (A8A906)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001434815.1
- ProteinModelPortal:   A8A906
- SMR:   A8A906
- STRING:   A8A906
- GeneID:   5562083
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0224
- eggNOG:   arNOG18251
- HOGENOM:   HBG553199
- OMA:   GSFAWVD
- ProtClustDB:   PRK00416
- BioCyc:   IHOS453591:IGNI_0224-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20517; Mature: 20517

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSDGGIKSYLRRGLMKIEPFDENQVRENGVDLTIGHQYARFKNTEDVLDVTKEEDLSK
CEECCCCHHHHHHHCCEECCCCCCCHHHHCCCEEEECCHHHHCCCCHHHHHHHHHHHHHH
YYELGFMDDEGIVIKPYEHVLLHTREYIEMPADLVGLVNLKSSFARLGLYIPPTVVDAGF
HHHCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
KGEIVIEIIGSSFPVRVRPGVPFIHLVFLRTDSPVLRDYSVRGHYQGQRGIRLPKLPIKL
CCCEEEEEECCCCCEEEECCCCEEEEEEEECCCCHHCCEECCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MILSDGGIKSYLRRGLMKIEPFDENQVRENGVDLTIGHQYARFKNTEDVLDVTKEEDLSK
CEECCCCHHHHHHHCCEECCCCCCCHHHHCCCEEEECCHHHHCCCCHHHHHHHHHHHHHH
YYELGFMDDEGIVIKPYEHVLLHTREYIEMPADLVGLVNLKSSFARLGLYIPPTVVDAGF
HHHCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
KGEIVIEIIGSSFPVRVRPGVPFIHLVFLRTDSPVLRDYSVRGHYQGQRGIRLPKLPIKL
CCCEEEEEECCCCCEEEECCCCEEEEEEEECCCCHHCCEECCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA