Click here to switch to the map view.

The map label for this gene is iucD [H]

Identifier: 156936669

GI number: 156936669

Start: 123680

End: 125002

Strand: Direct

Name: iucD [H]

Synonym: ESA_pESA3p05550

Alternate gene names: 156936669

Gene position: 123680-125002 (Clockwise)

Preceding gene: 156936668

Following gene: 156936670

Centisome position: 94.27

GC content: 60.09

Gene sequence:

>1323_bases
ATGAAAACGTACGATTTCATCGGCATTGGCATCGGCCCGTTCAATCTCAGCATCGCCGCGCTCGCCGAAGGGCTTGACGG
CTTCAGCTCGCTGTTTCTTGAACGCAAACCGCACTTCTCCTGGCATCCGGGCATGATGGTGCCGGACTGCCATATGCAGA
CCAGTTTCCTGAAAGATCTGGTCAGCGCGGTGGAGCCAACCAACCGTTACAGTTTTCTGAATTACCTGGTGCAGCGTAAA
AAGTTTTACCGTTTCCTGACCACCGAACAGCGCACGGTGTCCCGCGAAGAGTTCGCCGATTACCTCTGCTGGGCGGCGGA
TAACCTGAGCAATCTGTCGTTCAGCCAGCAGGTGCAGCAGGTGAGTTTTAACGAGGCCAGCGGGCTGTTTGAAGTGGTGA
CCCAGCGCGATCGTTTCTTCGCACGCCACGTCTGCATGGGCATCGGCAAACAGATTAACCTGCCCGACTGTGTGCCGGCG
CAGAACGACAGTTGCTTCCACGCCAGCGAAATGATGCTGCGTACGCCATCGCTTGCCGGTAAGCGCGTCACGGTCGTTGG
CGGCGGCCAGAGCGGCGCCGATCTGTTCCTGAATATTTTCCGCGGCGAGTGGGGCCAGCCCGCGGCACTGAACTGGGTGT
CGCGCCGCAACAATTACAACGCGCTCGATGAAGCCGCGTTCGCGAATGAATATTTCACGCCGGAATACCTTGAAAGCTTT
GCCACGCTCGATGAGAAAACGCGCTGCGATCTGCTCGCCGAACAGAAGATGACGTCTGACGGCGTGACCTGCGAATCGCT
GCTCGCTATCTATCGCGCCATGTACCACCGCTTTGAAGTGCTGCGTGAAAAACCCTGGGCGCAGCTGCTGCCGTCGCGCT
CGGTCACCCGCGTGACGTCACAGGCGCAGGGCCAGCGTCTGTCGCTGCGCCATCATCTGGACGGCGGCCAGGAAACGCTG
GATACCGATGTGGTGATTTTCGCGACCGGCTATCGCCCTGCCCGTCCGGCGTTCCTCGCCCCGCTGGCGCATCGGCTGGA
GCTGGACGAACGCGAAGGCTTCCGGGTTAATACCGATTTCACGCTGGCGTGGAACGGCCCCGGCGCAAACCATCTTTTTG
CCGTCAATGCCGGGATGCACAGCCTCGGCATTGCGGAACCCCAGCTCAGCCTGATGGCCTGGCGGGCCGCGCGCATTCTC
AATGTCGCGCACCCTGATGCGCCGTTTGAACTGAGCACCACCCCTGGCGTGATCCAGTGGCTTTCCCGGCCGGAAACGGT
CACCCGCCAGGTTTCTCAACCTGTAAACAGCACTGACTACTAA

Upstream 100 bases:

>100_bases
AGCTCACTTTCTCAGAGCATGACGGCGGCAGCCGCATGTTGCCCAATTACCTCACCGATCTTGATAACCCGCTGTATCTG
GTCACCAGGGAGACCGCATC

Downstream 100 bases:

>100_bases
CAGACTCAGGAACATCATAACAATGAAGCGTCATCATCTTTGGGTATTGAATCCTTGTTTACTTGCCATGATTTCTGCCT
CCGCCTGGGGGGCACCGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVEPTNRYSFLNYLVQRK
KFYRFLTTEQRTVSREEFADYLCWAADNLSNLSFSQQVQQVSFNEASGLFEVVTQRDRFFARHVCMGIGKQINLPDCVPA
QNDSCFHASEMMLRTPSLAGKRVTVVGGGQSGADLFLNIFRGEWGQPAALNWVSRRNNYNALDEAAFANEYFTPEYLESF
ATLDEKTRCDLLAEQKMTSDGVTCESLLAIYRAMYHRFEVLREKPWAQLLPSRSVTRVTSQAQGQRLSLRHHLDGGQETL
DTDVVIFATGYRPARPAFLAPLAHRLELDEREGFRVNTDFTLAWNGPGANHLFAVNAGMHSLGIAEPQLSLMAWRAARIL
NVAHPDAPFELSTTPGVIQWLSRPETVTRQVSQPVNSTDY

Sequences:

>Translated_440_residues
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVEPTNRYSFLNYLVQRK
KFYRFLTTEQRTVSREEFADYLCWAADNLSNLSFSQQVQQVSFNEASGLFEVVTQRDRFFARHVCMGIGKQINLPDCVPA
QNDSCFHASEMMLRTPSLAGKRVTVVGGGQSGADLFLNIFRGEWGQPAALNWVSRRNNYNALDEAAFANEYFTPEYLESF
ATLDEKTRCDLLAEQKMTSDGVTCESLLAIYRAMYHRFEVLREKPWAQLLPSRSVTRVTSQAQGQRLSLRHHLDGGQETL
DTDVVIFATGYRPARPAFLAPLAHRLELDEREGFRVNTDFTLAWNGPGANHLFAVNAGMHSLGIAEPQLSLMAWRAARIL
NVAHPDAPFELSTTPGVIQWLSRPETVTRQVSQPVNSTDY
>Mature_440_residues
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVEPTNRYSFLNYLVQRK
KFYRFLTTEQRTVSREEFADYLCWAADNLSNLSFSQQVQQVSFNEASGLFEVVTQRDRFFARHVCMGIGKQINLPDCVPA
QNDSCFHASEMMLRTPSLAGKRVTVVGGGQSGADLFLNIFRGEWGQPAALNWVSRRNNYNALDEAAFANEYFTPEYLESF
ATLDEKTRCDLLAEQKMTSDGVTCESLLAIYRAMYHRFEVLREKPWAQLLPSRSVTRVTSQAQGQRLSLRHHLDGGQETL
DTDVVIFATGYRPARPAFLAPLAHRLELDEREGFRVNTDFTLAWNGPGANHLFAVNAGMHSLGIAEPQLSLMAWRAARIL
NVAHPDAPFELSTTPGVIQWLSRPETVTRQVSQPVNSTDY

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 49584; Mature: 49584

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VSAVEPTNRYSFLNYLVQRKKFYRFLTTEQRTVSREEFADYLCWAADNLSNLSFSQQVQQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VSFNEASGLFEVVTQRDRFFARHVCMGIGKQINLPDCVPAQNDSCFHASEMMLRTPSLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
KRVTVVGGGQSGADLFLNIFRGEWGQPAALNWVSRRNNYNALDEAAFANEYFTPEYLESF
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHH
ATLDEKTRCDLLAEQKMTSDGVTCESLLAIYRAMYHRFEVLREKPWAQLLPSRSVTRVTS
HHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHH
QAQGQRLSLRHHLDGGQETLDTDVVIFATGYRPARPAFLAPLAHRLELDEREGFRVNTDF
HHCCCEEEHHHHCCCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEECCCE
TLAWNGPGANHLFAVNAGMHSLGIAEPQLSLMAWRAARILNVAHPDAPFELSTTPGVIQW
EEEECCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHH
LSRPETVTRQVSQPVNSTDY
HCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VSAVEPTNRYSFLNYLVQRKKFYRFLTTEQRTVSREEFADYLCWAADNLSNLSFSQQVQQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VSFNEASGLFEVVTQRDRFFARHVCMGIGKQINLPDCVPAQNDSCFHASEMMLRTPSLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
KRVTVVGGGQSGADLFLNIFRGEWGQPAALNWVSRRNNYNALDEAAFANEYFTPEYLESF
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHH
ATLDEKTRCDLLAEQKMTSDGVTCESLLAIYRAMYHRFEVLREKPWAQLLPSRSVTRVTS
HHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHH
QAQGQRLSLRHHLDGGQETLDTDVVIFATGYRPARPAFLAPLAHRLELDEREGFRVNTDF
HHCCCEEEHHHHCCCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEECCCE
TLAWNGPGANHLFAVNAGMHSLGIAEPQLSLMAWRAARILNVAHPDAPFELSTTPGVIQW
EEEECCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHH
LSRPETVTRQVSQPVNSTDY
HCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]