Definition Streptococcus pyogenes M1 GAS chromosome, complete genome.
Accession NC_002737
Length 1,852,441

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The map label for this gene is ymfH [H]

Identifier: 15675931

GI number: 15675931

Start: 1829659

End: 1830948

Strand: Reverse

Name: ymfH [H]

Synonym: SPy_2198

Alternate gene names: 15675931

Gene position: 1830948-1829659 (Counterclockwise)

Preceding gene: 15675932

Following gene: 15675930

Centisome position: 98.84

GC content: 31.94

Gene sequence:

>1290_bases
ATGACAAAATTAGTAAAGATAAACTATCCTAATATTGACGAAGACCTTTACTATGTAAAATTAGAAAATGGTTTAACTGT
TTATTTTATAAAAAAAATAGGGTTTTTAGAAAAAACAGCTATGTTGACAGTAGGTTTCGGTTCTCTTGACAATAAGTTGA
CAGTCGATGACGAATCACGAGATGCTCCAGCAGGTATTGCACACTTTTTAGAACATAAACTCTTTGAAGATGAATCAGGT
GGAGATATTTCATTAAAGTTTACACAGCTAGGAGCAGAGACAAATGCCTTTACAACTTTCAACCAAACGAGTTTCTTCTT
TTCAACAGCTAGTAAATTTCAGGAAAATTTGGAACTCCTTCAATATTTTGTTCTTTCTGCTAATATAACAGATGAATCTG
TTAGTAGAGAAAAAAAAATAATCGGGCAAGAAATTGATATGTATCAAGATGATGCTGACTACCGTGCATATAGTGGAATC
CTTCAGAACTTATTTCCAAAAACAAGTTTAGCTAATGATATTGCTGGCTCAAAAGCATCCATTCAAAAGATCACGAAAAT
ATTATTGGAAACGCATCATACTTATTTTTACCAACCTACTAATATGAGTCTATTCATTGTCGGTGATATTGATATTGACG
AAACTTTTTTAGCTATTCAAAGGTTTCAAACCACATTATCCTATCCAGATAGAAAAAGGGTAACTGTTGATCCTTTACAC
TATTATCCTGTCATTAAATCATCTTCTGTTGACATGGATGTTACTACTGCCAAGCTGGTTGTTGGTTTTCGAGGGTATCT
GACCTTAACTCAGCATTCACTATTAACGTATCGTATTGCCTTGAAGCTATTTTTATCAATGCTTATAGGTTGGACTTCTA
AAATCTATCATACGCTATATGAAGATGGTAAAATAGACGATTCATTTGATGTGGATGTTGAAATTCATCATAATTTTCAA
TTTGTATTAATATCACTTGATACACCAGAGCCTATCGCAATGTCTAACTATATCCGTCAAAAATTAGCTACTATAAAGAT
ATCAAAAGAGTTTACAAATGAGCACTTAAATCTATTAAAAAAAGAAATGTATGGTGACTTTATTCAGAGTTTAGACTCTA
TAGAACATTTAACCCATCAGTTCAGTCTATACCTGTCTGATTCTGATAAAGAAACATATTTTGATATTCCAAAAATTATA
GAAAGACTCACTCTAAAAGATGTTGTTACAATTGGAAAAGCATTTTTTGAAAAAGCTGATGCTTCAGACTTCACAGTCTT
CCCAAAATAG

Upstream 100 bases:

>100_bases
AATTGGATTAAAGGGGTTAATGAAGTTAATAAAGCAGATATCATTAAAGTAGCTAATCTTTTAAAGCTTCAAACTGTCTA
TTTTTTAGAAGGAATATAAA

Downstream 100 bases:

>100_bases
ATGAAAATCTGTTATAATAGGGTTACTATATTATTTTTGAGGTACCTGTATGAGTGAAAAAAGTCTTGGTGAAGTGTTAA
GAGAATCGCGTGTTGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESG
GDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
LQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLH
YYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQ
FVLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKII
ERLTLKDVVTIGKAFFEKADASDFTVFPK

Sequences:

>Translated_429_residues
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESG
GDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
LQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLH
YYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQ
FVLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKII
ERLTLKDVVTIGKAFFEKADASDFTVFPK
>Mature_428_residues
TKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGG
DISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGIL
QNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHY
YPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQF
VLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKIIE
RLTLKDVVTIGKAFFEKADASDFTVFPK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Escherichia coli, GI1787770, Length=234, Percent_Identity=25.2136752136752, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49187; Mature: 49055

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESR
CCEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCHHHEEEEEEECCCCCCEEEECCCCC
DAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELL
CCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHH
QYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGILQNLFPKTSLANDIAGSKAS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHH
IQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLH
HHHHHHHHHHHCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECCEE
YYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLY
EEEEEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLK
CCCCCCCCEEEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHH
KEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKIIERLTLKDVVTIGKAFFEKAD
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCC
ASDFTVFPK
CCCEEECCC
>Mature Secondary Structure 
TKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTVGFGSLDNKLTVDDESR
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCHHHEEEEEEECCCCCCEEEECCCCC
DAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELL
CCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHH
QYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGILQNLFPKTSLANDIAGSKAS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHH
IQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLH
HHHHHHHHHHHCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECCEE
YYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLY
EEEEEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLK
CCCCCCCCEEEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHH
KEMYGDFIQSLDSIEHLTHQFSLYLSDSDKETYFDIPKIIERLTLKDVVTIGKAFFEKAD
HHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCC
ASDFTVFPK
CCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]