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The map label for this gene is hutI [H]

Identifier: 15675839

GI number: 15675839

Start: 1731244

End: 1732530

Strand: Reverse

Name: hutI [H]

Synonym: SPy_2081

Alternate gene names: 15675839

Gene position: 1732530-1731244 (Counterclockwise)

Preceding gene: 15675848

Following gene: 15675836

Centisome position: 93.53

GC content: 41.41

Gene sequence:

>1287_bases
ATGTTAAAAAAGGAGGTTTTTATGGTTGCTGATGTCTTATTAACACATTTTAATCAACTATTTTGTCTAAATGATCCAGG
TCATCCTTTAACTGGTCAAGAAATGAAAAAAGCCACTATCGTTGAAGATGGCTATATAGCCATCAAAGACGGCCTCATTG
TGGCTCTTGGTTCTGGTGAACCAGATGCTGAGCTTGTCGGTACACAGACTATTATGCGTTCTTATAAAGGTAAAATTGCA
ACGCCTGGTATTATTGACTGTCATACCCATTTGGTCTATGGTGGCAGTCGTGAACATGAATTTGCCAAGAAATTAGCAGG
GGTGTCTTACTTGGATATTTTAGCTCAAGGTGGTGGTATTTTAAGCACGGTGAGGGCCACTCGGTCAGCCAGCTTTGACA
ACCTTTATCAAAAATCCAAGAGATTGCTAGACTACATGTTGCTTCATGGAGTGACTACTGTCGAAGCGAAAAGTGGCTAC
GGCCTTGATTGGGAAACAGAAAAACGCCAACTGGATGTTGTTGCTGCTTTAGAAAAAGACCATCCCATTGATTTGGTGTC
TACGTTTATGGCAGCCCATGCGATTCCTGAAGAATACAAAGGGAATCCTAAGGCTTATCTCGATGTGATTATCAAGGATA
TGCTTCCTGTTGTTAAAGAGGAAAATCTGGCAGAATTTTGTGATATTTTCTGTGAAAAAAATGTTTTTACAGCTGATGAG
TCTCGCTATCTGTTAAGCAAAGCCAAAGAAATGGGCTTCAAGCTTCGTATTCACGCAGATGAAATTGCGTCTATAGGCGG
AGTTGATGTCGCAGCAGAGCTCAGCGCAGTTAGTGCAGAGCATTTGATGATGATAACAGATGATGGTATCGCTAAGTTGA
TTGGTGCTGGTGTTATTGGTAATTTGCTTCCAGCCACCACCTTTAGTTTGATGGAAGACACTTATGCCCCTGCTCGCAAA
ATGATCGATGCTGGCATGGCCATCACCCTCTCAACAGATAGTAATCCAGGCAGTTGCCCGACTGCTAACATGCAGTTTGT
GATGCAATTAGGTTGTTTTATGTTACGTTTAACACCGATTGAAGTCTTAAATGCTGTTACCATTAACGCGGCCTACTCTG
TCAATCGTCAGGAGAGAGTTGGTAGTTTGACAGTTGGTAAAGAAGCAGATATTGCCATTTTTGATGCCCCAAATATTGAT
TACCCATTTTATTTCTTTGCCACCAACTTGATTCACCAAGTCTATAAAAAAGGACAACTCACAGTTGACCGAGGTCGTAT
TCTTTAA

Upstream 100 bases:

>100_bases
AGTCAGTCAGAGGTTAATTGTTGTTACCAAAGTTGCAAAGATCGCAACTATTGAGTGGGTGAGGGGGGACTAGTAATGGC
TATTAATCAGTTGACAAACG

Downstream 100 bases:

>100_bases
AAAATTTAAAAAAGAAGCTTTGAGCGTTAGCTCAAAACTTCTTTTAAATATGCTGTTTTATTGACGAATCAAGTAGTCAA
AGGCACCGATGGCAGCAGTA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGTQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL

Sequences:

>Translated_428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGTQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL
>Mature_428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGTQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=427, Percent_Identity=34.8946135831382, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17555004, Length=368, Percent_Identity=35.054347826087, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 46858; Mature: 46858

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHEEEECCEEEEECCEEEEECCCC
PDAELVGTQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGI
CCHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCH
LSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHEECCCC
HPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADE
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIG
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
NLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
EVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQL
HHHHHEEEEEEEECCHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
TVDRGRIL
EECCCCCC
>Mature Secondary Structure
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHEEEECCEEEEECCEEEEECCCC
PDAELVGTQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGI
CCHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCH
LSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHEECCCC
HPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADE
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIG
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
NLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
EVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQL
HHHHHEEEEEEEECCHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
TVDRGRIL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]