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The map label for this gene is prmA

Identifier: 15675778

GI number: 15675778

Start: 1658088

End: 1659041

Strand: Reverse

Name: prmA

Synonym: SPy_1988

Alternate gene names: 15675778

Gene position: 1659041-1658088 (Counterclockwise)

Preceding gene: 15675779

Following gene: 15675777

Centisome position: 89.56

GC content: 44.65

Gene sequence:

>954_bases
ATGGAAACGTGGCAAGAAGTGACGGTTCATGTGCATCGTGATGCGCAAGAGGCTGTTTCACATGTGTTGATTGAGACAGG
CAGTCAAGGGGTTGCTATCGCAGATAGCGCAGACTATATTGGGCAAAAGGACCGCTTTGGGGAGTTATACCCAGATGTGG
AGCAGTCTGACATGATAGCTATCACAGCCTATTACCCAAGTAGTACTAATTTGGCGGATATTATTGCGACCATTAATGAA
CAGTTAGCGGAGTTAGCTAGTTTTGGGTTACAGGTTGGTCAGGTTACTGTGGACAGTCAAGAATTGGCTGAGGAAGACTG
GGCAGACAATTGGAAAAAATACTATGAACCAGCTCGCATCACGCATGATTTAACCATTGTCCCTAGTTGGACGGATTATG
ACGCTTCTGCTGGGGAAAAAGTGATTAAACTAGATCCTGGAATGGCATTTGGGACAGGGACACATCCCACAACTAAGATG
AGCCTTTTTGCCTTGGAACAAATCCTTCGTGGTGGTGAGACAGTTATCGATGTAGGGACCGGTTCAGGTGTCCTCTCGAT
TGCCAGTTCCTTACTAGGTGCTAAAACCATCTACGCTTATGACTTAGATGACGTGGCTGTTCGAGTGGCTCAAGACAACA
TTGATTTAAACCAAGGAACAGACAACATTCATGTGGCTGCTGGTGACCTTTTAAAAGGGGTTAGCCAAGAAGCGGATGTG
ATTGTAGCCAATATCTTGGCGGATATCTTAGTCTTATTGACTGATGATGCTTACCGTTTGGTCAAAAAGGAAGGTTACCT
TATCTTATCTGGCATCATTTCTGAGAAATTGGATATGGTTCTGGAAGCTGCCTTTAGCGCAGGCTTTTTCTTAGAAACTC
ACATGGTTCAAGGTGAGTGGAATGCCCTTGTCTTTAAAAAAACAGATGATATCTCAGGAGTGATTGGCGGCTAA

Upstream 100 bases:

>100_bases
GCAGCAAGTTACCCTTACCCAAGGTACTAAGGTGACACATGAGATGGTGCTAACACTATTAGGACAATAACCAAAAGGTC
AAAATAGAAAGGACATAACT

Downstream 100 bases:

>100_bases
TGCAACAGTATTTTATTAAAGGCAAAGCAGAAAAAAAGGTAACGATTACCGATAAAGATACCATCAAGCACATGTTTCAA
GTGATGCGCTTGGCTGACGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAITAYYPSSTNLADIIATINE
QLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQGTDNIHVAAGDLLKGVSQEADV
IVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG

Sequences:

>Translated_317_residues
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAITAYYPSSTNLADIIATINE
QLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQGTDNIHVAAGDLLKGVSQEADV
IVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG
>Mature_317_residues
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAITAYYPSSTNLADIIATINE
QLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQGTDNIHVAAGDLLKGVSQEADV
IVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=309, Percent_Identity=32.0388349514563, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_STRP1 (Q99XW8)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269952.1
- RefSeq:   YP_283058.1
- ProteinModelPortal:   Q99XW8
- SMR:   Q99XW8
- EnsemblBacteria:   EBSTRT00000000216
- EnsemblBacteria:   EBSTRT00000028175
- GeneID:   3571210
- GeneID:   901656
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1988
- KEGG:   spz:M5005_Spy_1695
- GeneTree:   EBGT00050000028027
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   SPYO160490:SPY1988-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1695-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34304; Mature: 34304

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIA
CCCHHEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCEEE
ITAYYPSSTNLADIIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARI
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECEEEECHHHHHHHHHHHHHHHHCCCCCE
THDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQILRGGETVIDVGT
EEEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQGTDNIHVAAGDLLKGVSQEADV
CCCHHHHHHHHHCCCEEEEECCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHCCCCCHHH
IVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEW
HHHHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
NALVFKKTDDISGVIGG
CEEEEEECCCCCCCCCC
>Mature Secondary Structure
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIA
CCCHHEEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCEEE
ITAYYPSSTNLADIIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARI
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECEEEECHHHHHHHHHHHHHHHHCCCCCE
THDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQILRGGETVIDVGT
EEEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQGTDNIHVAAGDLLKGVSQEADV
CCCHHHHHHHHHCCCEEEEECCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHCCCCCHHH
IVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEW
HHHHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
NALVFKKTDDISGVIGG
CEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296