| Definition | Streptococcus pyogenes M1 GAS chromosome, complete genome. |
|---|---|
| Accession | NC_002737 |
| Length | 1,852,441 |
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The map label for this gene is exp5 [H]
Identifier: 15675776
GI number: 15675776
Start: 1654795
End: 1656981
Strand: Reverse
Name: exp5 [H]
Synonym: SPy_1986
Alternate gene names: 15675776
Gene position: 1656981-1654795 (Counterclockwise)
Preceding gene: 15675777
Following gene: 15675775
Centisome position: 89.45
GC content: 44.44
Gene sequence:
>2187_bases ATGAAAACATCATTCAAGCAACTGTTTCGTTTCGAATTTTGGCAAAAATTTGGGAAATGTCTTATGGTCGTTATTGCTGT CATGCCAGCGGCTGGTTTAATGATCAGTATCGGAAACTCTATTCCAATGATTAACCACGACTCAGCATTTTTGGCATCTC TAGGCAACATTATCGCTCAAATTGGTTGGGCTGTTATTGTTAACCTTCACTTGCTATTTGCCTTGGCCATTGGTGGTAGT TGGGCTAAAGAAAGAGCTGGAGGGGCCTTTGCCTCAGGGCTTGCTTTTGTCTTGATCAATCGGATAACAGGTGCTTTTTA TGGCGTGTCTAGTACTATGCTAGCTGATCCAGAAGCAAAAATCACAAGCCTCCTTGGCACTCAAATGATCGTTAAAGATT ATTTCACCAGTGTCTTGGAATCTCCAGCTTTAAACACAGGGGTTTTTGTTGGGATTATTGCAGGGTTCGTAGGAGCAACG GCCTATAACAAATACTATAATTACCGTAAACTTCCTGAAGTTTTGACCTTCTTTAATGGGAAGCGTTTTGTACCATTTGT CGTTATTTTACGTTCTATTTTTGTAGCCCTTATTTTGGTTGTTGTTTGGCCGGTGATCCAGTCTGGGATTAACAGTTTTG GGATGTGGATTGCCTCTTCACAAGATTCAGCTCCAATCCTAGCCCCATTCCTATATGGTACCTTGGAACGTCTCTTGTTG CCATTTGGTCTTCACCACATGTTGACGATCCCAATGAACTATACAGCTCTTGGTGGAACTTATGAGGTCATGACAGGTGC AGCAGCGGGGACAAAAGTATTTGGTCAAGACCCTTTGTGGCTTGCTTGGGTAACTGACCTTGTTCACCTTAAAGGATCAG ACGCTTCAGCCTATAGTCACTTAATGGATAGTGTGACTCCAGCTCGTTTCAAAGTAGGACAAATGATTGGAGCTACCGGA ACATTGATGGGGGTTGCCTTAGCCATGTACCGTAATGTGGATGCCGATAAAAAACACACATACAAAATGATGTTCATCTC AGCAGCGGCAGCGGTCTTTTTGACAGGGGTAACTGAGCCACTTGAGTACCTATTTATGTTTGCAGCAATGCCACTTTACA TCGTCTATGCCCTTGTTCAAGGAGCTTCATTTGCCATGGCAGACCTTGTGAATCTCCGTGTTCACTCATTTGGAAATATA GAGCTACTAACCCGCACCCCTATGGCTCTTAAAGCAGGCCTAGGCATGGATGTGATTAACTTTGTTTGGGTTTCTGTCCT CTTTGCAGTTATCATGTACTTTATTGCAGATATGATGATCAAGAAAATGCATCTCGCAACAGCTGGCCGTTTAGGCAACT ACGATGCCGATATACTGGGTGACCGTAACACTCAAACAAGACCTACCCAAGTAGCAGATAGCAACTCTCAAGTCGTGCAA ATCGTTAATCTCCTTGGTGGGGCAGGCAATATTGATGATGTTGATGCTTGTATGACGCGCTTACGAGTGACGGTCAAAGA CCCCGCTAAGGTTGGTGCTGAGGACGATTGGAAAAAAGCTGGCGCTATAGGCTTGATCCAAAAAGGCAACGGCGTTCAAG CGGTCTATGGCCCTAAAGCAGATATTTTGAAATCAGATATTCAAGATTTGCTGGACTCAGGTGCTCTTATTCCAGAAGTC AATATGTCACAGCTCACTAGCAAACCGACTCCCGCAAAAGATTTTAAACACGTGACAGAAGATGTGCTATCAGTGGCAGA CGGGATGGTTCTCCCAATCACAGGTGTAAAAGACCAGGTGTTTGCGGCTAAGATGATGGGAGATGGGTTTGCGGTTGAAC CAACCCATGGTAATATCTATGCACCCGTAGCTGGCCTTGTGACCAGTGTCTTTCCGACCAAGCATGCCTTTGGTTTACTG ACAGATAATGGTCTTGAAGTGCTGGTGCACGTGGGACTTGATACCGTCGCCTTAAATGGTGTGCCTTTTTCAGTCAAAGT CTCAGAAGGGCAACGGGTTCATGCAGGTGACCTATTAGTCGTAGCAGATCTTGCTGCTATTAAATCAGCAGAGCGTGAAA CAATCATTGTTGTTGCTTTTACCAACACAACAGAGATCCAAGATGTGACCTTGACATCTTTAGGAGCTCAGCCTGCTAAG ACTAAAGTAGCTACCGTAGAACTTTAA
Upstream 100 bases:
>100_bases TGCAAGCGATTGCATCACTGAGTTGCTGTCTATATCATTGTGTCACAAAAGCGCCTTAAGGGCAGCTATGGCTAAAAGGG GATAATAAAGGAGAGATAGA
Downstream 100 bases:
>100_bases CAAAACATCACGAGATAGTGATAGGTAATAGCCATAGCTGGTTTAGGCCCTATGGCTCTTCTTGTCTTATAAAGGAGGAT TAATGACCAAGGTATTAACA
Product: PTS system glucose-specific transporter subunit IIABC
Products: NA
Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]
Number of amino acids: Translated: 728; Mature: 728
Protein sequence:
>728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQ IVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAK TKVATVEL
Sequences:
>Translated_728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQ IVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAK TKVATVEL >Mature_728_residues MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGS WAKERAGGAFASGLAFVLINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATG TLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNI ELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQ IVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEV NMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLL TDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAK TKVATVEL
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1786894, Length=718, Percent_Identity=31.7548746518106, Blast_Score=259, Evalue=6e-70, Organism=Escherichia coli, GI1787343, Length=542, Percent_Identity=30.2583025830258, Blast_Score=218, Evalue=9e-58, Organism=Escherichia coli, GI1787908, Length=555, Percent_Identity=30.2702702702703, Blast_Score=213, Evalue=3e-56, Organism=Escherichia coli, GI1790159, Length=128, Percent_Identity=39.0625, Blast_Score=102, Evalue=1e-22, Organism=Escherichia coli, GI1788757, Length=149, Percent_Identity=35.5704697986577, Blast_Score=102, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011300 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 78194; Mature: 78194
Theoretical pI: Translated: 7.05; Mature: 7.05
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHH IGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSSTMLADPEAK HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHH ITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNG HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC KRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSH HHCCHHHEEECCCEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH LMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEP HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH LEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDVIN HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHH FVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHH IVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKA HHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCHHHCCCEEEEECCCCEEEEECCCH DILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQV HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHH FAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNG HHHHHCCCCEEECCCCCCEECCHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCEEEECC VPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAK CCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHCCCCCCC TKVATVEL CCEEEEEC >Mature Secondary Structure MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCHHHHHHHHHHHHH IGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSSTMLADPEAK HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHH ITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNG HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC KRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLL CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH PFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSH HHCCHHHEEECCCEEECCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH LMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEP HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH LEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDVIN HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHH FVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHH IVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKA HHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCHHHCCCEEEEECCCCEEEEECCCH DILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQV HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHH FAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNG HHHHHCCCCEEECCCCCCEECCHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCEEEECC VPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAK CCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHCCCCCCC TKVATVEL CCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11463916; 7934910 [H]