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The map label for this gene is yacO [H]

Identifier: 15675741

GI number: 15675741

Start: 1612590

End: 1613336

Strand: Reverse

Name: yacO [H]

Synonym: SPy_1938

Alternate gene names: 15675741

Gene position: 1613336-1612590 (Counterclockwise)

Preceding gene: 15675742

Following gene: 15675740

Centisome position: 87.09

GC content: 38.69

Gene sequence:

>747_bases
ATGGAAGATAAAGATACTATTGAAACAAACGATATCGTCTATGGTGTTCATGCCGTTACAGAAAGCCTTCAAGCAAATAC
AGGAAATAAGCTTTATATCCAAGAGGATTTAAGAGGAAAGAAAGTGGATAACATCAAAAGCTTAGCGACACAAAAAAAGG
TCGCTATTTCATGGACGCCTAAAAAAACCTTGTCACAAATGACTGATGGAGCTGTGCATCAAGGTTTTGTTCTGAGAGTA
TCAGCTTTTGCCTATACTGATGTTGATGAGATCCTCGAAATAGCAGAGCAAGAAGCAAATCCTTTGATTCTTATTTTAGA
TGGTCTGACAGATCCTCATAATTTAGGATCGATTTTACGGACAGCTGATGCTACAAATGTATGTGGAGTGATTATTCCTA
AACATCGTTCTGTTGGTGTGACTCCAGTGGTTTCAAAGACGTCTACAGGTGCTGTTGAACATATTCCGATAGCGAGAGTA
ACTAACCTTAGTCAAACTCTAGATAAATTGAAAGCAAGAGGATTCTGGATTTTTGGCACAGACATGAATGGAACACCGTC
TGATTGCTGGAACACTAATGGTAAACTTGCTTTAGTCATTGGTAACGAAGGTAAAGGCATCTCTACCAATATCAAAAAGC
AAGTTGATGAAATGATTACGATTCCTATGAATGGTCACGTACAGAGCTTAAATGCTAGCGTAGCGGCAGCTATTCTCATG
TATGAAGTTTTCCGAAATAGGCGCTAA

Upstream 100 bases:

>100_bases
AGTTTAGCTGCAGGTTTATTTATAGCTATTCAAAAAGTATCTAGACGAAAATAAAAGAGTCTATGCATTTATTTTGAAGC
ATTCATGGTATAATAAACTC

Downstream 100 bases:

>100_bases
ATTATGAAAAAACGGATATTATTAGTAGATGGGTATAATATGATTGCCTTTTGGCAATCAACCCGTCAGTTGTTTAAGAC
AAATCAGCTTGATCAGGCAC

Product: putative tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRV
SAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILM
YEVFRNRR

Sequences:

>Translated_248_residues
MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRV
SAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILM
YEVFRNRR
>Mature_248_residues
MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRV
SAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILM
YEVFRNRR

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=272, Percent_Identity=28.6764705882353, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1790623, Length=242, Percent_Identity=37.1900826446281, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790083, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788935, Length=154, Percent_Identity=26.6233766233766, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=35.7575757575758, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27039; Mature: 27039

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVAISWTP
CCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEECC
KKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILR
HHHHHHHHCCCCCCCEEEEEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
TADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGT
HCCCCCCEEEEEECCCCCCCCEEECCCCCCCEECCCHHHHHHHHHHHHHHHHCEEEEEEC
DMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILM
CCCCCCCHHCCCCCEEEEEECCCCCCCCCHHHHHHHHEEECCCCCCEEHHHHHHHHHHHH
YEVFRNRR
HHHHHCCC
>Mature Secondary Structure
MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVAISWTP
CCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEECC
KKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILR
HHHHHHHHCCCCCCCEEEEEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
TADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGT
HCCCCCCEEEEEECCCCCCCCEEECCCCCCCEECCCHHHHHHHHHHHHHHHHCEEEEEEC
DMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILM
CCCCCCCHHCCCCCEEEEEECCCCCCCCCHHHHHHHHEEECCCCCCEEHHHHHHHHHHHH
YEVFRNRR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]