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The map label for this gene is pepXP

Identifier: 15675679

GI number: 15675679

Start: 1541907

End: 1544189

Strand: Direct

Name: pepXP

Synonym: SPy_1858

Alternate gene names: 15675679

Gene position: 1541907-1544189 (Clockwise)

Preceding gene: 15675678

Following gene: 15675680

Centisome position: 83.24

GC content: 39.77

Gene sequence:

>2283_bases
ATGCGCTATAATCAATTTTCCTATATTCCAACTAGTCTAGAAAGAGCGGCTGAAGAATTAAAAGAATTGGGCTTTGATCT
GGATCTGCAAAAAACTGCCAAAGCTAGCCTAGAAAGCTTTTTACGTAAACTCTTCTTCCACTACCCTGATAGTGATTATC
CTTTAAGTCATCTAATCGCCAAAAATGACATGGACGCATTGAGCTTTTTTCAATCAGAGCAAGAGTTATCCAAAGAGGTT
TTTGATTTACTGGCCCTGCAAGTCCTTGGCTTTATTCCTGGAGTTGATTTTACAGAGGCCGATGCTTTCCTTGATAAACT
GGCCTTTCCTATCCACTTTGACGAAACAGAAATTATCAAGCATATCCACCACTTATTAGCGACCCGTTGTAAGTCTGGCA
TGACCCTGATTGATGATTTGGTCAGCCAAGGAATGCTTACTATGGACAATGATTACCACTTCTTCAACGGTAAATCATTA
GCTACCTTTGACACGTCACAGCTGATTCGAGAAGTTGTTTACGTTGAAGCACCTCTTGATACCGATCAAGATGGCCAACT
TGATCTTATTAAGGTTAATATCATTCGTCCTCAATCTCAAAAACCATTACCAACTTTGATGACACCTAGTCCATACCATC
AAGGTATCAATGAAGTAGCCAACGACAAAAAACTTTATCGTATGGAAAAAGAGTTAGTCGTTAAAAAAAGGAGACAAATC
ACTGTCGAAGACAGGGATTTTATTCCTCTTGAGACACAGCCTTGCAAACTTCCTATAGGTCAAAATCTAGAAAGCTTTAG
CTACATTAACTCCTATAGCCTCAACGATTATTTCCTCGCACGTGGGTTTGCTAATATCTATGTTTCAGGTGTGGGAACTG
CTGGTTCCACTGGCTTTATGACGAGTGGAAACTATGCTCAAATTGAAAGCTTTAAAGCCGTTATTGATTGGCTAAATGGA
AGAGCCACAGCCTACACCAGCCACTCAAAAACCCACCAAGTGAGAGCTGATTGGGCAAATGGTCTAGTTTGTACGACTGG
AAAGTCCTACTTGGGAACTATGTCTACTGGTTTAGCCACTACAGGCGTAGACGGATTAGCCATGATTATTGCAGAATCAG
CTATTTCTTCTTGGTACAACTACTACCGCGAAAATGGCTTAGTTTGTAGTCCTGGTGGCTATCCTGGAGAGGATCTAGAT
GTCTTAACTGAGCTCACCTACTCGCGTAATTTATTGGCTGGCGATTATCTTCGCCATAATGATCGTTATCAAGAATTGCT
AAACCAACAGTCTCAGGCGTTAGACCGACAATCTGGTGATTATAATCAATTTTGGCACGACCGCAATTACTTAAAAAATG
CTCATCAAATAAAGTGTGATGTCGTTTATACTCATGGCTTACAAGACTGGAATGTCAAACCAAGACAGGTCTATGAGATT
TTCAATGCGCTTCCTTCCACAATCAACAAGCACCTCTTTTTACATCAAGGTGAGCATGTTTACATGCATAATTGGCAATC
CATTGATTTTCGCGAAAGCATGAATGCCCTTTTATGTCAAAAACTCTTAGGCCTAGCTAATGATTTTAGCCTTCCTGAAA
TGATCTGGCAGGATAACACCTGCCCACAAAACTGGCAGGAGCGTAAAGTCTTTGGAACCTCAACCATCAAAGAGCTTGAC
CTCGGTCAGGAACTGCTTTTAATTGATAATCACTATGGTGAAGATGAATTTAAAGCTTACGGTAAAGATTTCCGTGCGTT
CAAAGCAGCTCTCTTTAAAGGCAAGGCCAATCAAGCCCTGATTGATATTTTACTGGAAGAGGACTTACCTATTAACGGTG
AAATTGTCCTACAGTTAAAAGTGAAATCAAGTGAAAATAAAGGACTTCTATCTGCACAAATCCTTGACTATGGTAAGAAA
AAACGCTTGGGCGATCTTCCTATTGCTCTCACCCAATCAAGTATTGACAATGGGCAAAATTTCTCTAGGGAACCCCTTAA
AGAGCTACCATTTAGAGAAGATTCTTACCGTGTTATTTCGAAAGGTTTCATGAATTTACAAAATCGCAATAATTTGTCGT
CAATTGAAACTATTCCTAATAATAAATGGATGACTGTTAGACTTCCTTTGCAACCAACCATCTATCATCTAGAAAAAGGA
GATACCCTTCGAGTCATCTTATACACAACCGATTTTGAACATACTGTCCGTGACAACAGCAACTATGCTTTAACTATCGA
TCTCAGTCAGTCTCAATTGATTGTGCCAATAGCATCAAATTAA

Upstream 100 bases:

>100_bases
AAAAAACATCATTCGCATTGATAAACAACATATTATCATTACCAATCTTGATAAATTAAAAGATAATATCGTTTTCTAAG
CCACTAGAAAGGAAACTCCT

Downstream 100 bases:

>100_bases
CAAAGAAAAGTGCTTAGCAATATAACTAAGCACTTTTTTGTTAATTGGTCTTACTAATAGCAAACAGAAAACGATCGTCT
TAGTTCATAAATTCCGAATC

Product: x-prolyl-dipeptidyl aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN

Sequences:

>Translated_760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
>Mature_760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGNYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN

Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S15 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPX_STRP1 (Q99Y58)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269853.1
- RefSeq:   YP_282940.1
- ProteinModelPortal:   Q99Y58
- SMR:   Q99Y58
- EnsemblBacteria:   EBSTRT00000000961
- EnsemblBacteria:   EBSTRT00000029077
- GeneID:   3571305
- GeneID:   902070
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1858
- KEGG:   spz:M5005_Spy_1577
- GeneTree:   EBGT00050000027432
- HOGENOM:   HBG515455
- OMA:   NDWNVKP
- ProtClustDB:   PRK05371
- BioCyc:   SPYO160490:SPY1858-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1577-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00698
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR008252
- InterPro:   IPR000383
- InterPro:   IPR015251
- PRINTS:   PR00923
- SMART:   SM00939
- SMART:   SM00940

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N; SSF49785 Gal_bind_like; SSF81761 PepX_N

EC number: =3.4.14.11

Molecular weight: Translated: 86739; Mature: 86739

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: ACT_SITE 349-349 ACT_SITE 469-469 ACT_SITE 499-499

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH
HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD
HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC
TDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCE
TSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT
ECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH
TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT
HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQAL
CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
IDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN
HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC
FSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKASLESFLRKLFFHYPDSDYPLSHLIA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH
HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD
HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC
TDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCE
TSGNYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT
ECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH
TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
FNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT
HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQAL
CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
IDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN
HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC
FSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296