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The map label for this gene is pncA [H]

Identifier: 15675617

GI number: 15675617

Start: 1468354

End: 1468908

Strand: Reverse

Name: pncA [H]

Synonym: SPy_1776

Alternate gene names: 15675617

Gene position: 1468908-1468354 (Counterclockwise)

Preceding gene: 15675618

Following gene: 15675616

Centisome position: 79.3

GC content: 36.04

Gene sequence:

>555_bases
ATGAGAGCATTGATTTCAATTGATTACACAAATGATTTTGTAGCAGATGATGGTAAATTAAGTGCAGGTAAATCTGCTCA
GGCTATTGCCACTAAAATAGCAGAGGTAACTAAAACGGCATTTGATCAAGGAGACTATATTTTTTTTGCTATTGATTGTC
ATGATCAAAATGATTCTTGGCATCCTGAGAGTAAGCTATTTGCAGCACATAATATCAAAGGAACTACTGGACGCCATCTT
TATGGTCCACTAGCTGAAGTTTACAGTTATATGAAGCAACATCCCAGAGTTTTTTGGATTGATAAGCGTTATTATTCAGC
TTTTTCGGGGACTGATTTAGATATTAGACTACGAGAAAGAGGTATCACTCAATTAGTGTTAACAGGAGTTTTATCTGATA
TCTGTGTCTTACATACTGCTATTGACGCTTATCATCTTGGTTATCAATTAGAGATTGTTAAATCGGCTGTCGCTAGCCTT
ACAAAAGAATCTTATGAGTGGTCTTTGGCTCACTTTGAGCAGGTTCTTGGTGCTAAGCTTATTAACGATTACTAA

Upstream 100 bases:

>100_bases
ATGGTAGATGCAAATAGATGTCTTGATACCTGTAATAAAAACTGATACAATGCCATATATAAGAGATAAGGGGAGAGGTT
TCCCTGTTTAGGAGATAGTG

Downstream 100 bases:

>100_bases
AAGAGCCTACCAAACTATTGATTCAGTGACTAAGAGTTTGGTAACCGTAATCATTGCTCTATGTGGTTTTACCGTATGTA
TGGGTTAGGTAGATGAGGTA

Product: putative pyrazinamidase/nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
TKESYEWSLAHFEQVLGAKLINDY

Sequences:

>Translated_184_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
TKESYEWSLAHFEQVLGAKLINDY
>Mature_184_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
TKESYEWSLAHFEQVLGAKLINDY

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: 3.5.1.-; 3.5.1.19

Molecular weight: Translated: 20744; Mature: 20744

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSW
CCEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
HPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRER
CCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCEEEEEHHC
GITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASLTKESYEWSLAHFEQVLGAKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
INDY
HCCC
>Mature Secondary Structure
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSW
CCEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
HPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRER
CCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCEEEEEHHC
GITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASLTKESYEWSLAHFEQVLGAKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
INDY
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]