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The map label for this gene is fabD [H]

Identifier: 15675599

GI number: 15675599

Start: 1450999

End: 1451937

Strand: Reverse

Name: fabD [H]

Synonym: SPy_1750

Alternate gene names: 15675599

Gene position: 1451937-1450999 (Counterclockwise)

Preceding gene: 15675600

Following gene: 15675598

Centisome position: 78.38

GC content: 39.94

Gene sequence:

>939_bases
ATGACAAAGACAGCCTTTTTATTTGCCGGTCAAGGTGCTCAAAAATTAGGGATGGCAAGGGATTTTTATGATAACTTTGC
TATTGTAAGAAAAACCTTTGATCAAGCTAGTCAAGTATTGGGATACGATTTGCGCCGTTTGATTGATAGTGACGAGTTAA
AACTTAATCAAACTAGCTATACGCAACCAGCTATTTTGACATCATCAATTGCTATTTACCGTGTTTTGGGCTTACATCAC
GTTAAACCGGATATGGTAGCTGGTCTTTCCTTAGGAGAATACTCAGCTTTGGTAGCATCAGGGGCACTCTCTTTTGAAGA
TACCCTATCCTTAGTAGCTAAGAGAGGCCGCTTGATGGAGGAAGCAGCACCACAAGGATCTGGAAAGATGGTTGCCGTTA
TGAATACAGACGTGCAAGTCATCGAAGAAGTCTGTCAAATAGCTGCTAAACATGGAGTGGTTGCTCCAGCAAACTATAAT
ACTCCTAGTCAAATTGTAATTGGTGGTCAGACAGATGCTGTGAACGTGGCAGTTGAACTTTTAAAGGAAAGGGGAGTTAA
GCGTTTAATCCCTTTAAACGTGTCAGGTCCTTTCCACACTGCTTTGTTAGAACCAGCTAGCCGCTTGTTGGCTAAAGAGT
TGGAAAGATACAACTTCAGTGACTTCAAGATTCCTTTGGTTGGTAATACCGAAGCTAATATTATGGAAAAAGACCGTATC
CCAGAACTATTAGCCCGTCAAGTCATGGAGCCTGTTCGTTTTTATGACAGTGTTGCGACTTTAGTAGAAAGTGGCATAAC
ACAATTCATTGAGGTAGGACCAGGTAAGGTTTTGACAGGTTTTGTGAAGAAAATTGATAAAAATTTACTATGTACTAGTG
TTGAAAACATGGTAAGCTTACGTTTATTTTTAGATAGAGAGGACATTCATGGAAATTAA

Upstream 100 bases:

>100_bases
AGATATTTATTATGGTGCAGCTCGTGTTATTCAAAATGAAGCTAAGCGCTGGCAATCTGTTTCAATAGAAAAGTAGATAA
ACACATGAAGGATAATGATA

Downstream 100 bases:

>100_bases
AGGAAAAAATATATTTATCACAGGCTCAACGAGAGGTATCGGTTTAGCAATGGCTCATCAATTCGCCAGTTTAGAAGCTA
ATATTGTCTTAAATGGTCGC

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDLRRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHH
VKPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRI
PELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN

Sequences:

>Translated_312_residues
MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDLRRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHH
VKPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRI
PELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN
>Mature_311_residues
TKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDLRRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHV
KPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYNT
PSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRIP
ELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=306, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=39.6396396396396, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=42.5324675324675, Blast_Score=232, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.3993174061433, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=29.9319727891156, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=30.6930693069307, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34215; Mature: 34084

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDLRRLIDSDELKLNQTSY
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
TQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLME
CCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYNTPSQIVIGGQTDAVNVAVEL
HHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEECCCCCCCCCEEEECCCCHHHHHHHHH
LKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRI
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCH
PELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSVENMVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLFLDREDIHGN
HHEEECCCCCCC
>Mature Secondary Structure 
TKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDLRRLIDSDELKLNQTSY
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
TQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLME
CCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYNTPSQIVIGGQTDAVNVAVEL
HHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEECCCCCCCCCEEEECCCCHHHHHHHHH
LKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRI
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCH
PELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSVENMVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLFLDREDIHGN
HHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]