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The map label for this gene is lacA.1

Identifier: 15675561

GI number: 15675561

Start: 1415927

End: 1416352

Strand: Reverse

Name: lacA.1

Synonym: SPy_1708

Alternate gene names: 15675561

Gene position: 1416352-1415927 (Counterclockwise)

Preceding gene: 15675562

Following gene: 15675560

Centisome position: 76.46

GC content: 42.02

Gene sequence:

>426_bases
ATGGCTATTATTTTAGGTGCAGATGCACACGGAAATGCATTAAAAGAATTGATCAAAAGTTTTCTTCAAGAAGAAGGCTA
TGACATTATTGACGTGACTGATATTAACAGTGATTTTATTGATAACACATTAGCGGTGGCGAAAGCCGTTAATGAAGCAG
AAGGTCGTTTAGGCATTATGGTGGATGCTTACGGAGCAGGTCCCTTTATGGTAGCCACAAAATTAAAAGGAATGGTTGCT
GCTGAAGTGTCAGATGAACGCTCTGCTTACATGACGCGCGGTCACAACAATGCCCGCATGATCACAATAGGGGCAGAGAT
TGTAGGTCCAGAATTAGCGAAGAATATCGTCAAAGGTTTTGTGACTGGTCCCTACGATGGTGGTCGTCATCAAATTCGTG
TTGACATGCTCAATAAAATGGCCTAA

Upstream 100 bases:

>100_bases
AAGACACTAAGACTACTGGCAATCATCTTGATCTAAGGACAGGTAATCATGTCCCCCTTCTCTAGATTGGCAAGCGTTTT
GGGTTAGAAAAGGAAAAGCT

Downstream 100 bases:

>100_bases
AGGAGGATAAAGTGATGAAAATTGCGATTGGTTGTGACCATATTGTCACCAACGAAAAAATGGCTGTTTCTGATTTTTTG
AAATCTAAAGGCTATGACGT

Product: galactose-6-phosphate isomerase subunit LacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVA
AEVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA

Sequences:

>Translated_141_residues
MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVA
AEVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA
>Mature_140_residues
AIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAA
EVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=143, Percent_Identity=34.965034965035, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACA1_STRP1 (Q99YH1)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269735.1
- RefSeq:   YP_282761.1
- ProteinModelPortal:   Q99YH1
- SMR:   Q99YH1
- EnsemblBacteria:   EBSTRT00000000687
- EnsemblBacteria:   EBSTRT00000028383
- GeneID:   3571513
- GeneID:   901947
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1708
- KEGG:   spz:M5005_Spy_1398
- GeneTree:   EBGT00050000027285
- HOGENOM:   HBG636953
- OMA:   SAMASNK
- ProtClustDB:   PRK12613
- BioCyc:   SPYO160490:SPY1708-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1398-MONOMER
- HAMAP:   MF_01555
- InterPro:   IPR004783
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01118
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 15127; Mature: 14995

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIM
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
VDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGF
EEECCCCCCHHHHHHCCEEEECCCCCHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHC
VTGPYDGGRHQIRVDMLNKMA
CCCCCCCCCEEEEEEEHHCCC
>Mature Secondary Structure 
AIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIM
EEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
VDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGF
EEECCCCCCHHHHHHCCEEEECCCCCHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHC
VTGPYDGGRHQIRVDMLNKMA
CCCCCCCCCEEEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296