Definition Streptococcus pyogenes M1 GAS chromosome, complete genome.
Accession NC_002737
Length 1,852,441

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The map label for this gene is glyQ [H]

Identifier: 15675549

GI number: 15675549

Start: 1403677

End: 1404594

Strand: Reverse

Name: glyQ [H]

Synonym: SPy_1689

Alternate gene names: 15675549

Gene position: 1404594-1403677 (Counterclockwise)

Preceding gene: 15675550

Following gene: 15675548

Centisome position: 75.82

GC content: 42.81

Gene sequence:

>918_bases
ATGTCTAAAAAACTTACCTTTCAAGAAATCATCTTGACCTTACAACAATATTGGAATGATCAGGGTTGTATGCTCATGCA
AGCCTATGACAATGAAAAAGGAGCTGGGACCATGAGTCCTTACACGTTCTTACGTGCTATAGGTCCTGAGCCATGGAATG
CGGCTTATGTAGAGCCATCACGTCGTCCTGCAGATGGCCGTTACGGAGAAAACCCAAATCGTCTTTACCAACACCACCAA
TTTCAAGTGGTCATGAAACCATCACCATCAAATATTCAAGAACTTTACCTTGCTTCTTTGGAAAAATTGGGCATCAATCC
TTTAGAACATGATATTCGTTTTGTTGAAGATAACTGGGAAAACCCATCAACAGGATCAGCAGGGCTTGGTTGGGAAGTTT
GGCTTGATGGAATGGAAATCACACAATTTACGTATTTCCAACAAGTTGGTGGCCTTGCGACATCTCCAGTGACAGCAGAA
GTAACTTATGGTCTTGAGCGCTTAGCTTCCTATATTCAAGAAGTGGATTCGGTCTATGATATTGAGTGGGCACCAGGTGT
TAAATATGGTGAAATCTTCTTACAACCTGAGTATGAACATTCAAAATATTCCTTCGAAATATCAGACCAAGACATGCTGC
TTGAAAACTTTGAAAAGTTTGAAAAAGAAGCCTCGCGTGCCCTAGAAGAAGGTTTGGTTCACCCAGCTTATGATTACGTG
CTCAAATGTTCTCATACGTTTAACCTGCTGGATGCCCGTGGCGCTGTTTCCGTCACAGAACGTGCAGGCTACATTGCTCG
TATCCGTAATTTGGCACGTGTCGTTGCTAAGACCTTTGTTGCAGAACGCAAGAAGCTTGGATTTCCACTGTTGGATGAAG
CAACACGCGCAATCTTGCTAGCTGAAGATGACGAATAA

Upstream 100 bases:

>100_bases
GACCTGTAATACATGCTAGTAACATCGTCAGGTATTTTACTGATGACAAAAAAACGATTGTCAATGATATACCATTTTAC
TACTATCAAAGGAGTACGAA

Downstream 100 bases:

>100_bases
GTCGATTTAAAGATGATCTAGTTGCGAGCTTTGTAATCTTAAGAGCGAGCAAGAAGTGGGCGACCGAAGGTCGCCGAGTC
AAGGTTACTCCCGCTGTAGT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQ
FQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYV
LKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE

Sequences:

>Translated_305_residues
MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQ
FQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYV
LKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE
>Mature_304_residues
SKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQF
QVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEV
TYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYVL
KCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=62.9251700680272, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006194
- InterPro:   IPR002310 [H]

Pfam domain/function: PF02091 tRNA-synt_2e [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 34834; Mature: 34702

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPS
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCEEECCC
RRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWE
CCCCCCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHEEEECCCC
NPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYD
CCCCCCCCCCHHEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEE
IEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYV
CCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILL
EECCCHHEEHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEE
AEDDE
ECCCC
>Mature Secondary Structure 
SKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPS
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCEEECCC
RRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWE
CCCCCCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHEEEECCCC
NPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYD
CCCCCCCCCCHHEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEE
IEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYV
CCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILL
EECCCHHEEHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEE
AEDDE
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12122206; 12799345 [H]