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The map label for this gene is sunL [H]

Identifier: 15675503

GI number: 15675503

Start: 1348372

End: 1349694

Strand: Reverse

Name: sunL [H]

Synonym: SPy_1627

Alternate gene names: 15675503

Gene position: 1349694-1348372 (Counterclockwise)

Preceding gene: 15675504

Following gene: 15675502

Centisome position: 72.86

GC content: 39.08

Gene sequence:

>1323_bases
TTGGCAGATAATTGGAAAAAAAGTACGCGAGGCAAAGCCCTCCTTGTCATTGAAGCTATTTTTGATCAGGGGGCTTACAC
AAACATAGCGCTTAATCAGCAACTAAGCAATAAAGCTTTATCTGCTAAGGACAGAGCTCTATTAACTGAGATTGTATATG
GTACCGTTTCACGTAAAATTAGCTTGGAATGGTATTTAGCCCATTATGTCAAAGACCGAGATAAATTGGACAAATGGGTT
TATTATCTCCTTATGCTCAGTCTTTATCAACTGACTTATTTAGATAAGTTACCAGCGCATGCCATTGTTAACGATGCGGT
TGGTATTGCCAAAAATCGTGGCAATAAAAAAGGTGCAGAGAAGTTTGTCAATGCTATTTTACGTCAATTCACCAGCCATC
CTCTCCCAGATATGGAAACAATTAAGCGTCGAAATAAGTATTATTCGGTCAAGTATTCACTGCCTGTTTGGTTGGTTAAA
AAGTTAGAAGACCAATTTGGTTCTGACAGATCAGTGGCCATCATGGAAAGTTTATTTGTGCGTAGTAAGGCTAGTATTCG
CGTGACAGACCCTTTGAAGCTAGAGGAAGTTGCTGAGGCTTTAGATGCAGAACGTTCCCTTTTATCAGCAACTGGTTTAA
CCAAAGCGTCAGGTCATTTTGCAGCCAGTGATTATTTCACAAATGGGGACATCACTATTCAAGATGAAAGCAGTCAGCTT
GTAGCTCCTACTTTAAACATTGACGGTGACGACATAATTCTTGATGCGTGTAGCGCTCCAGGGGGCAAGACCTCTCATAT
AGCATCTTACTTAAAAACAGGTAAAGTTATTGCCTTAGATCTCTATGATCATAAACTAGAGTTGGTGAAGGAAAATGCTA
ACCGCTTAGGAGTTGCTGATAACATTGAGACAAGAAAACTAGATGCCAGAGAGGTTCATCGTCATTTTGAAAAGGATAGC
TTTGATAAGATTTTGGTGGATGCTCCTTGCTCAGGAATTGGTTTGATTCGTCGAAAACCCGATATCAAATATAATAAAGA
AAGTCAAGGTTTCAATGCTCTGCAAGCTATCCAGCTAGAGATATTGTCTAGTGTTTGTCAAACCTTGCGTAAAGGTGGTA
TAATAACATACAGTACTTGCACTATTTTTGATGAGGAGAATCGTCAAGTCATCGAAGCATTTTTACAGAGTCATCCTAAT
TTTGAACAAGTAAAACTGAACCATACACAAGCAGATATTGTCAAGGATGGTTATCTTATTATCACACCAGAACAATACCA
GACTGATGGCTTCTTTATTGGACAAGTCAGACGAGTCTTGTAG

Upstream 100 bases:

>100_bases
GCTTTGTCCTTGATCGTTGTGCAACCGGCTGGTAAACCTAAAATGTCAATAATAGACTTTTTAAACGGCATTGGTAGAAA
ACTTGAAGTAGGGGACATCA

Downstream 100 bases:

>100_bases
TATTTTAGGAGGAAACTGACTGAGTCAGAAAAAACGTATGAAGATTTCATTAAAAACAGACATTGGGCAAAAACGCTCAA
ACAATCAAGATTTTATCAAT

Product: 16S rRNA m(5)C 967 methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKDRALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWV
YYLLMLSLYQLTYLDKLPAHAIVNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASGHFAASDYFTNGDITIQDESSQL
VAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKVIALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDS
FDKILVDAPCSGIGLIRRKPDIKYNKESQGFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIEAFLQSHPN
FEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL

Sequences:

>Translated_440_residues
MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKDRALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWV
YYLLMLSLYQLTYLDKLPAHAIVNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASGHFAASDYFTNGDITIQDESSQL
VAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKVIALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDS
FDKILVDAPCSGIGLIRRKPDIKYNKESQGFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIEAFLQSHPN
FEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL
>Mature_439_residues
ADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKDRALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVY
YLLMLSLYQLTYLDKLPAHAIVNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVKK
LEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASGHFAASDYFTNGDITIQDESSQLV
APTLNIDGDDIILDACSAPGGKTSHIASYLKTGKVIALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSF
DKILVDAPCSGIGLIRRKPDIKYNKESQGFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIEAFLQSHPNF
EQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=330, Percent_Identity=31.2121212121212, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI76150623, Length=330, Percent_Identity=31.2121212121212, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32698918, Length=181, Percent_Identity=36.4640883977901, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI8922322, Length=236, Percent_Identity=28.3898305084746, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI23199998, Length=236, Percent_Identity=28.3898305084746, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI270288816, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI270288818, Length=236, Percent_Identity=28.3898305084746, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI39995082, Length=230, Percent_Identity=30, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI301336155, Length=241, Percent_Identity=29.4605809128631, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI11545785, Length=159, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI2367212, Length=463, Percent_Identity=29.5896328293737, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081985, Length=220, Percent_Identity=30.9090909090909, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17536757, Length=239, Percent_Identity=31.7991631799163, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=30.2222222222222, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=30.2222222222222, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=239, Percent_Identity=31.3807531380753, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324306, Length=207, Percent_Identity=28.0193236714976, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI22024126, Length=239, Percent_Identity=30.5439330543933, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355201, Length=193, Percent_Identity=31.6062176165803, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24668781, Length=182, Percent_Identity=31.3186813186813, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21356513, Length=178, Percent_Identity=32.0224719101124, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356579, Length=223, Percent_Identity=27.8026905829596, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49555; Mature: 49424

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKDRALLTEIVYGTVSRKI
CCCCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHCHHHHHHHHHHHHHHHHHEE
SLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAIVNDAVGIAKNRGNKKGAE
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
KFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVKKLEDQFGSDRSVAIMESLFV
HHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHH
RSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASGHFAASDYFTNGDITIQDESSQL
HCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEECCEEEEEECCCEE
VAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKVIALDLYDHKLELVKENANRLGVAD
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCCCC
NIETRKLDAREVHRHFEKDSFDKILVDAPCSGIGLIRRKPDIKYNKESQGFNALQAIQLE
CCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
ILSSVCQTLRKGGIITYSTCTIFDEENRQVIEAFLQSHPNFEQVKLNHTQADIVKDGYLI
HHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHEEEECCCHHHHCCCCEEE
ITPEQYQTDGFFIGQVRRVL
ECCCCCCCCCEEHHHHHHCC
>Mature Secondary Structure 
ADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKDRALLTEIVYGTVSRKI
CCCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHCHHHHHHHHHHHHHHHHHEE
SLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAIVNDAVGIAKNRGNKKGAE
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
KFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVKKLEDQFGSDRSVAIMESLFV
HHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHH
RSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASGHFAASDYFTNGDITIQDESSQL
HCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEECCEEEEEECCCEE
VAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKVIALDLYDHKLELVKENANRLGVAD
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCCCC
NIETRKLDAREVHRHFEKDSFDKILVDAPCSGIGLIRRKPDIKYNKESQGFNALQAIQLE
CCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
ILSSVCQTLRKGGIITYSTCTIFDEENRQVIEAFLQSHPNFEQVKLNHTQADIVKDGYLI
HHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHEEEECCCHHHHCCCCEEE
ITPEQYQTDGFFIGQVRRVL
ECCCCCCCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]