| Definition | Streptococcus pyogenes M1 GAS chromosome, complete genome. |
|---|---|
| Accession | NC_002737 |
| Length | 1,852,441 |
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The map label for this gene is licR [H]
Identifier: 15675268
GI number: 15675268
Start: 1099291
End: 1101285
Strand: Reverse
Name: licR [H]
Synonym: SPy_1325
Alternate gene names: 15675268
Gene position: 1101285-1099291 (Counterclockwise)
Preceding gene: 15675269
Following gene: 15675267
Centisome position: 59.45
GC content: 38.35
Gene sequence:
>1995_bases ATGTTATCAAAAAAAGAACTGGCCATCATAACATTTCTAATCCATCACAAAGAGCAGTTTGTCTCTAGTGCAACTCTGGC TGAGGTTATCGGTATGAGTGACCGTACGGTTAGGAAATACCTCAAAGAACTGATCAGTAGCCTTCCTGAACACGGAGCTC ACATCATTTCTAAACAAGGTCGAGGTTACTGCTTAGAAATTGACCATTCTATGGCATTTGACATCTTTTGGCAAGAAAGT GTGACGTCTAAAAAACGTTTGGCAGATGTGACTCAAGTGGAAGAATCGGTTGATCGAGAAGATTATGTGCTTCATAAATT CTTTTTTGAAGATGCCGTTCAGGATTTTGAAGAGCTTTGTCAAGAATTGTATATCAGTCGGACAACTTTAAAACATGTTT TAGCAGGTATTAAGGAGCGCATAATACCTTACCAGTTAGAGCTTGAAATAACTCACCAACATATTCAAATAAGAGGTAAA GAAGAGGACATTAGGCATTTTATCATGGACTATTTTTTTGTTACTAGTTTTGATAATACCTTGTCCACCATGGTAGGTAA TACCTTTCTTGAAGGTATTAATTTTGCAGAAATCATGATTATTGTCTTGGATGAATGTCGGGATGCTAAGTTGAAACTTT CTGATTTTGTCATGAATAATCTAGTCTTGCATATTGCCCTAATGGTTCAGCGTATTCGATCGGGGTGTCCATTAGAACTG TTTTCCATTCCAATAGCTATTCGTCAGTCTGATGAGTATCAAGTAGCTCTGCGCATTTTGTATCGAGTGGAAGAAGTGAT GGGGATACGTTTTCCTAAAGAGGAGGCTAATTATATTGCACTGCATCTAAAGGTCAAACATTCTGTTGGTAAGCATTGGC AAGATGATAATACCGATGAAAAGTTGCAGGACCATTTAAAAGCATGTATTGCCAAGATTAGTCAATTGACAGGCATGACT TTAGAAACAGATACCAATTTATTTCAAGGTTTATTAGCCCACATGATGCCCTTGACCATACGTCTTGAAAACCATATTCA GCTGACTAATCCTTTAACTGAGGAAATTAAAAGCCAGTATCCTGAAATATTTACCCTTACCAAGCAGACCTTTTCGGATT TGCTTGTATGTCAAAAGAATGATGTCTCAGATGATGAATGGGCTTATATTAGTTTGCATTTAATGGCGGCCATTGAGCGT TATTCAAACCGTCATAAATTGAGGGTTCTAGTAGTTTGTGCCACAGGTTATGGTAGTGCCATGATGTTGAAAAATCGCTT GGAAAAGGAATTTGAAGGACGTTTGCGTATTGTCGATGTTATCAGTTACTATGAAATAACCGAAGAGCGACTGAAAACCG TTGATTTGATTATTTCCTCTATCAGCCTTGCCAATCTGATGTTTTTAACACCAGTGATTACTGTCAGTGTTTTTTTGTCA AATCAGGATATTGAAACTATTCGACAATTTATTGGAGAACAAGAAGGTATCAAGAAAGAGGTCAGTTTACCGTCACAGAT GAGTTTAGCAAAAGCAGAGCAGCTTCTAACAGGTGTTTTTAGCCCTAATCGTTTTCTTTATTTAGACGAGAAAATCTCAA AGGAAGACTTGCTTTTACGGATGATTGCTTGTCTTGACGAGGCGGGAACAGAAACGTTTGTAGAGGACTTCTATCATCAA ATGGTACTGAGGGAAAATTACAGCCCAGTCATCTATGGAGAAGTGCTTGCCTTTCCGCATCCTGCTAATCCCATGACTTA TTCTGAACAGGTAGTAGTGGTTATTTGCCGAGAGCCTCTTGAGTGGGACAAGGCGCATCAAGCTGTTCATTTTGTCTTTC TATTATCCCCGTCTAAAGGGCATAATCATAGGTTAAAATATGTATCACCAGGTTTGGCATCTTTTGTCAATCAGGTGGAG CTTCAGCAAGCGTTACTAGAAGAACCAAATTATTCCAAATTCATGACAGTGTTTACCCCACTTATTCATGATTAA
Upstream 100 bases:
>100_bases TTTCACAATCAATGCGGAAAATGATGGTCACCTTTTTCAGGAAATATTTGGTACACTAAAGGAGGGTAGAAAGCGTTTTC TAAAGTAGTAAGGAGGACTA
Downstream 100 bases:
>100_bases AACGATTAAAAGGAGAAACCTTATGAAATCTATTATGTTAGTTTGTAATGCCGGTATGTCAACTAGTATGTTGGTGACTA AGATGCAAAAAGCAGCCCAA
Product: BglG family transcription antiterminator
Products: NA
Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 664; Mature: 664
Protein sequence:
>664_residues MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTIRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLTPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYSKFMTVFTPLIHD
Sequences:
>Translated_664_residues MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTIRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLTPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYSKFMTVFTPLIHD >Mature_664_residues MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQES VTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLEL FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMT LETDTNLFQGLLAHMMPLTIRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIER YSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLTPVITVSVFLS NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQ MVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPLEWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVE LQQALLEEPNYSKFMTVFTPLIHD
Specific function: Positive regulator of the licABCH operon [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 76685; Mature: 76685
Theoretical pI: Translated: 5.56; Mature: 5.56
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC RGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELC CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH QELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGKEEDIRHFIMDYFFVTSFDNT HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCHH LSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLEL HHHHHHHHHHCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE EECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCHH KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTIRLENHIQLTNPLTEEIKSQY HHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCEEEEEECCEEECCHHHHHHHHHC PEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIERYSNRHKLRVLVVCATGYGSA CCEEEHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH MMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLTPVITVSVFLS HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLR CCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH MIACLDEAGTETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPL HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHEEECCCCCCCCCCCCCEEEEEECCCC EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTP CHHHHHCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH LIHD HHCC >Mature Secondary Structure MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKELISSLPEHGAHIISKQG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC RGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDYVLHKFFFEDAVQDFEELC CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH QELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGKEEDIRHFIMDYFFVTSFDNT HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCHH LSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVMNNLVLHIALMVQRIRSGCPLEL HHHHHHHHHHCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE FSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEANYIALHLKVKHSVGKHWQDDNTDE EECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCHH KLQDHLKACIAKISQLTGMTLETDTNLFQGLLAHMMPLTIRLENHIQLTNPLTEEIKSQY HHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCEEEEEECCEEECCHHHHHHHHHC PEIFTLTKQTFSDLLVCQKNDVSDDEWAYISLHLMAAIERYSNRHKLRVLVVCATGYGSA CCEEEHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH MMLKNRLEKEFEGRLRIVDVISYYEITEERLKTVDLIISSISLANLMFLTPVITVSVFLS HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC NQDIETIRQFIGEQEGIKKEVSLPSQMSLAKAEQLLTGVFSPNRFLYLDEKISKEDLLLR CCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH MIACLDEAGTETFVEDFYHQMVLRENYSPVIYGEVLAFPHPANPMTYSEQVVVVICREPL HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHEEECCCCCCCCCCCCCEEEEEECCCC EWDKAHQAVHFVFLLSPSKGHNHRLKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTP CHHHHHCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH LIHD HHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8990303; 8969509; 9384377; 10438772 [H]