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The map label for this gene is exuR [H]

Identifier: 15675250

GI number: 15675250

Start: 1075601

End: 1076401

Strand: Direct

Name: exuR [H]

Synonym: SPy_1297

Alternate gene names: 15675250

Gene position: 1075601-1076401 (Clockwise)

Preceding gene: 15675249

Following gene: 15675263

Centisome position: 58.06

GC content: 39.08

Gene sequence:

>801_bases
ATGATGACATCTAAAATTACCATTAAAGATATTGCACGAGAAGCCGGGGTTTCTGTGGCGACCGTATCTTACGTGTTAAA
CCAGCGCAATGATCAAAAAATCAGCGAAGAAACCCGCAATAAAGTGCTACATATTAGTAACCTTCTTAACTATACACCTA
ATCAGGCAGCCAGGTCATTAGTCACACAACAATCAAACAGTGTTGTCCTGTATTACAAATATGCAGATAGCATTTTAGCT
AGGGCTGAACAACTGCATACCATTAGCTTTCTATCCCGCCTATTGCATGAGCAGGACTATCAGCTGGTTTGCCTAAATGA
AGATAGCACTGAAAAATTTGACTGGGCAGACCTTATTCTGACCTTGGACGTTGATAATGATACCTTTTACAAAATTGGAA
AGCTTAATTTCAAACCCTTAATTGCCATTGATAGCTTTGTTAATGATCCCCTCTTCTTTCAAATTAATACAGATTATGCT
GCTCTCAAAGATCAGGCTAATCAGTTTTTTAAGGATGAACCTTATACCCTGCTTTCCTTGCCTATCACTAATCGTGAGCG
ATATGAGCATGTTTCTGCCTTCTTTCCAAGTTTGCACATTGTAAACGACCTAAGAGAGCTAACCTACTTTGAAAAGGAAA
ATCTTTTACTCATTGATGAGAGTTTGGATCAATTCTTTGTGAACTCTTCGCAAAAACTCTACTGCCCACGTTTTTCCCCC
AAAAAAGGGCAAGTTATCTTAGAGGCCATCGAATGGGCCAAAAAACGCCAGCCTGATAAAAAACATAACCTTCTGGTGTA
A

Upstream 100 bases:

>100_bases
TAAGGCCGTAGATAATCATATTAGTCCTCACATTTATCTTCAGATCAGCCAAATGTATTAATGATTCCTTGACTTTTACC
ATGAATTCGGATATAACAAA

Downstream 100 bases:

>100_bases
CGCCTGAGAATTAACCTATCTTGACTAATTCCTTGTAACTCAAAACCTTGCCTCTTTAGATAAAGAAGCAAGGTTTTTTG
ATGTCTAATCTAATAACAGG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILA
RAEQLHTISFLSRLLHEQDYQLVCLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYA
ALKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSP
KKGQVILEAIEWAKKRQPDKKHNLLV

Sequences:

>Translated_266_residues
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILA
RAEQLHTISFLSRLLHEQDYQLVCLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYA
ALKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSP
KKGQVILEAIEWAKKRQPDKKHNLLV
>Mature_266_residues
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILA
RAEQLHTISFLSRLLHEQDYQLVCLNEDSTEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYA
ALKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSP
KKGQVILEAIEWAKKRQPDKKHNLLV

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 30926; Mature: 30926

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLNYTPNQAARSL
CCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHEEHHHHHHCCCCCHHHHHH
VTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLVCLNEDSTEKFDWADLIL
HHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
TLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAALKDQANQFFKDEPYTLLSL
EEECCCCCEEEEECCCCCEEEEEHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEE
PITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCEEECCCCCC
KKGQVILEAIEWAKKRQPDKKHNLLV
CCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHISNLLNYTPNQAARSL
CCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHEEHHHHHHCCCCCHHHHHH
VTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLVCLNEDSTEKFDWADLIL
HHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEE
TLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAALKDQANQFFKDEPYTLLSL
EEECCCCCEEEEECCCCCEEEEEHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEE
PITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLIDESLDQFFVNSSQKLYCPRFSP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCEEECCCCCC
KKGQVILEAIEWAKKRQPDKKHNLLV
CCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]