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The map label for this gene is cdd [H]

Identifier: 15675193

GI number: 15675193

Start: 1014774

End: 1015163

Strand: Reverse

Name: cdd [H]

Synonym: SPy_1230

Alternate gene names: 15675193

Gene position: 1015163-1014774 (Counterclockwise)

Preceding gene: 15675194

Following gene: 15675192

Centisome position: 54.8

GC content: 35.38

Gene sequence:

>390_bases
ATGGGGACTACTGATTTAGTTAGTTGTGCTGTACAAGCTAGTGAGTATGCTTATGTCCCTTACTCTCATTTTCCAGTAGG
AGCAGCTTTAAAAACAAAAGATGGAACGATCTATACTGGCTGTAATATTGAAAATGTTAGTTTTGGTCTGACAAATTGTG
GAGAGCGAACAGCTATATTTAAAGCCATATCTGATGGTCATAAAGAATTGGTTGAAATTGCTATTTATGGAGAAACTATG
CAACCTGTATCTCCTTGTGGGGCTTGTCGTCAGGTAATGGCAGAATTTTTTGATCCTTCTTCTTTAGTCACTTTAATTGC
TAAAAATGGTCAAACTGTTGAAATGACTGTTGGAGATTTACTCCTCTATTCTTTTACAGATTTAATATAA

Upstream 100 bases:

>100_bases
AAGTTAGATCACGTTAATTATCTATCAAGTCGGGTGCATATTTCGTTAAAGTATCTACAGGGGTTTCAATAGATGTAGCT
ATTATGAAAGGTGATGTTAA

Downstream 100 bases:

>100_bases
TCTGCTTTAATTTCTGTTATCTAGCCGTCTTGGCTTTATATTTACTTTCAGCAACTTATTTGCTAGAAATCTTTTTTAGG
AGGGTTCATATTCATGAACA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETM
QPVSPCGACRQVMAEFFDPSSLVTLIAKNGQTVEMTVGDLLLYSFTDLI

Sequences:

>Translated_129_residues
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETM
QPVSPCGACRQVMAEFFDPSSLVTLIAKNGQTVEMTVGDLLLYSFTDLI
>Mature_128_residues
GTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQ
PVSPCGACRQVMAEFFDPSSLVTLIAKNGQTVEMTVGDLLLYSFTDLI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=50, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=45.0819672131148, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17551074, Length=121, Percent_Identity=45.4545454545455, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=119, Percent_Identity=37.8151260504202, Blast_Score=84, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24582741, Length=105, Percent_Identity=44.7619047619048, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920920, Length=94, Percent_Identity=48.936170212766, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582744, Length=98, Percent_Identity=45.9183673469388, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13860; Mature: 13729

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIF
CCCHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCEEEECCCCCCCEECCCCCCCHHHHH
KAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSLVTLIAKNGQTVEMTVGDL
HHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECCCCEEEEEHHHH
LLYSFTDLI
HHHHHHHCC
>Mature Secondary Structure 
GTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIENVSFGLTNCGERTAIF
CCHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCEEEECCCCCCCEECCCCCCCHHHHH
KAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSLVTLIAKNGQTVEMTVGDL
HHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECCCCEEEEEHHHH
LLYSFTDLI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]