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The map label for this gene is csrA

Identifier: 15675047

GI number: 15675047

Start: 865046

End: 865483

Strand: Direct

Name: csrA

Synonym: SPy_1055

Alternate gene names: 15675047

Gene position: 865046-865483 (Clockwise)

Preceding gene: 15675046

Following gene: 15675048

Centisome position: 46.7

GC content: 41.78

Gene sequence:

>438_bases
ATGGAAACATCAGATGAGTTAAAACAACGCATTGGTGATCTTTCTTACGAGGTCACCCAGCATGCAGCAACAGAATCTCC
CTTTACAGGAGAATATGATAATTTTTTTGAGAAGGGTATCTATGTCGATATCGTCAGTGGTGAGGTCTTGTTTTCATCAC
TGGATAAATTTAATTCTGGCTGTGGTTGGCCTGCCTTTTCAAAACCTATTGAAAATCGTATGGTCACAAACCACGATGAC
TCTTCTTATGGGATGAGACGAGTTGAGGTTAAAAGCCGTGAAGCAGGATCGCATTTGGGGCATGTCTTTAGTGACGGCCC
CAAAGAAGCTGGAGGCTTGCGTTACTGTATCAATTCAGCAGCTCTTAAATTTATTCCTTATGACCAGATGGAAAAAGAAG
GCTATGCCCAATGGCTCACATTGTTTGATGAGACATAA

Upstream 100 bases:

>100_bases
TAGGTATAACGTCTTGTCTGAGGTGCTGTGAACAAATCAGTTACCGCTCACCTCTTTTTTTGGTAAAATGTAAGCACTAA
AACATCAAAAGGAGTTTTCC

Downstream 100 bases:

>100_bases
CAGGGTTTCAAAATGACTGAAATTCCCACAAGCACTGGATTGGTGAGGCGTACGGGTCAGTTTTACAAGCCTTTGTAAAA
GGTCTATAATAGGGAATGAA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET

Sequences:

>Translated_145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>Mature_145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=50.7936507936508, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=52.0325203252033, Blast_Score=129, Evalue=7e-31,
Organism=Homo sapiens, GI117606353, Length=129, Percent_Identity=39.5348837209302, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=40.9836065573771, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=124, Percent_Identity=45.1612903225806, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115532676, Length=124, Percent_Identity=45.1612903225806, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=119, Percent_Identity=38.655462184874, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=48.8, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=48.8, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=48.8, Blast_Score=125, Evalue=9e-30,
Organism=Drosophila melanogaster, GI221378664, Length=122, Percent_Identity=48.3606557377049, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI221378662, Length=129, Percent_Identity=45.7364341085271, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=44.1176470588235, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=44.1176470588235, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_STRP1 (Q99ZV6)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269221.1
- RefSeq:   YP_282141.1
- ProteinModelPortal:   Q99ZV6
- SMR:   Q99ZV6
- EnsemblBacteria:   EBSTRT00000001242
- EnsemblBacteria:   EBSTRT00000027499
- GeneID:   3572143
- GeneID:   901183
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1055
- KEGG:   spz:M5005_Spy_0778
- GeneTree:   EBGT00050000027538
- HOGENOM:   HBG715255
- OMA:   EPLFASA
- ProtClustDB:   PRK00222
- BioCyc:   SPYO160490:SPY1055-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0778-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 16354; Mature: 16354

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECHHHHHHHHHHHCCC
CGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSA
CCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKFIPYDQMEKEGYAQWLTLFDET
HHEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECHHHHHHHHHHHCCC
CGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSA
CCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKFIPYDQMEKEGYAQWLTLFDET
HHEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296