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The map label for this gene is glmM

Identifier: 15675035

GI number: 15675035

Start: 848795

End: 850150

Strand: Direct

Name: glmM

Synonym: SPy_1038

Alternate gene names: 15675035

Gene position: 848795-850150 (Clockwise)

Preceding gene: 15675034

Following gene: 15675036

Centisome position: 45.82

GC content: 42.26

Gene sequence:

>1356_bases
ATGGGAAAATATTTTGGAACAGATGGTGTTCGTGGCGAAGCAAATGTTGAGCTGACACCTGAGTTAGCTTTTAAACTGGG
CCGATTCGGTGGTTATGTTTTAAGTCAACATGAGACCGAAAGACCTAAAGTTTTTGTGGCGCGTGACACCCGTATTTCAG
GAGAAATGTTGGAGTCAGCCTTGATTGCTGGTCTACTATCTGTTGGTATTGAAGTTTATAAACTTGGCGTTTTAGCGACA
CCTGGTGTCTCTTATTTAGTTAGAACAGAAAAAGCAAGTGCAGGTGTGATGATTTCTGCAAGTCATAACCCTGCGCTTGA
CAATGGCATCAAATTCTTTGGGAATGATGGGTTTAAGTTAGCTGATGACCAAGAATTGGAAATTGAAGCTCTCTTAGATG
CTCCGGAGGACACGCTTCCTCGCCCGAGTGCAGAAGGACTTGGAACCTTGGTAGATTATCCAGAAGGACTTCGTAAATAT
GAAAAGTTCTTGGTAACAACTGGTACTGACTTAAGCGGTATGACAGTTGCCTTAGACACTGCTAATGGAGCTGCTTCAGT
GTCAGCACGTGATGTCTTTTTAGATTTAAATGCAGAAATTGCTGTCATTGGTGAAAAACCAAATGGTCTTAATATTAATG
ACGGTGTTGGTTCAACGCGTCCAGAACAACTTCAAGAGTTAGTTAAGGAAACAGGAGCAGATCTTGGTTTAGCCTTTGAT
GGCGATAGCGACCGTCTGATTGCTGTGGACGAAACTGGCGAGATTGTTGACGGTGATCGTATTATGTTTATCATTGGTAA
ATATTTGTCAGAAAAAGGGCTTCTTGCTCACAATACCATTGTCACAACGGTGATGTCTAACCTCGGTTTTCATAAAGCTT
TAGATAAACAAGGTATTAATAAAGCAATTACAGCAGTTGGAGACCGCTATGTGGTTGAAGAAATGCGTAGCTCAGGATAC
AATCTCGGTGGTGAACAATCAGGCCATGTCATTATCATGGACTACAATACCACTGGAGATGGTCAGTTGACAGCTATCCA
ATTAGCCAAGGTGATGAAGGAAACTGGAAAATCACTTTCGGAATTAGCTGCTGAAGTAACCATTTACCCTCAAAAACTGG
TGAATATTCGTGTGGAAAACAGCATGAAAGAACGTGCTATGGAAGTTCCAGCTATTGCGAACATCATTGCAAAAATGGAG
GATGAAATGGCTGGTAATGGTCGTATTCTCGTGAGACCAAGTGGTACAGAACCTCTTCTTCGTGTCATGGCAGAGGCGCC
AACAGATGCCGAAGTTGATTATTATGTCGATACTATTGCTGATGTCGTCCGTACAGAAATCGGATGCGATAACTAA

Upstream 100 bases:

>100_bases
TTGAGCCGTCAGTAGTGACCGTTCAGTTGACAACCACCAAAAAATAATGGATAATAACTAGGAAAATTGAATGGAGGAAG
CCATTAGGCTTATATAAATT

Downstream 100 bases:

>100_bases
CGAGTTGAGTACAAACAAGAAACCTTATTTCTAAGGCTTCTGTCAACAATTGGAAAGAGGCTTGGGGCGTTTAGCCCAAG
TCTCTTTTTATAAATTGTTA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLAT
PGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTRPEQLQELVKETGADLGLAFD
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGY
NLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKME
DEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

Sequences:

>Translated_451_residues
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLAT
PGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTRPEQLQELVKETGADLGLAFD
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGY
NLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKME
DEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>Mature_450_residues
GKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATP
GVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYE
KFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTRPEQLQELVKETGADLGLAFDG
DSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYN
LGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMED
EMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=43.4977578475336, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1788361, Length=455, Percent_Identity=25.9340659340659, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_STRP1 (Q99ZW8)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269209.1
- RefSeq:   YP_282126.1
- ProteinModelPortal:   Q99ZW8
- EnsemblBacteria:   EBSTRT00000001127
- EnsemblBacteria:   EBSTRT00000029199
- GeneID:   3572128
- GeneID:   901170
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1038
- KEGG:   spz:M5005_Spy_0763
- GeneTree:   EBGT00050000026762
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14316
- BioCyc:   SPYO160490:SPY1038-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0763-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48415; Mature: 48283

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESA
CCCCCCCCCCCCCCCEEECHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCCHHHHHHH
LIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKL
HHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCEE
ADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDT
CCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHEEEECCCCCCCEEEEEEC
ANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTRPEQLQELVKETGADLGLAFD
CCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGIN
CCCCCEEEEECCCCEECCCEEEEEEEHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHCCHH
KAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLS
HHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
ELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLL
HHHHHEEEECHHHEEEEECCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESA
CCCCCCCCCCCCCCEEECHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCCHHHHHHH
LIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKL
HHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCEE
ADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDT
CCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHEEEECCCCCCCEEEEEEC
ANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTRPEQLQELVKETGADLGLAFD
CCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGIN
CCCCCEEEEECCCCEECCCEEEEEEEHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHCCHH
KAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLS
HHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
ELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLL
HHHHHEEEECHHHEEEEECCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296