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The map label for this gene is cpsFP

Identifier: 15674954

GI number: 15674954

Start: 776671

End: 777264

Strand: Direct

Name: cpsFP

Synonym: SPy_0935

Alternate gene names: 15674954

Gene position: 776671-777264 (Clockwise)

Preceding gene: 15674953

Following gene: 15674955

Centisome position: 41.93

GC content: 40.24

Gene sequence:

>594_bases
ATGACAGAAACTTTTTTTGACAAACCATTGGCTTGCCGAGAAATCAAAGAAATCCCAGGCTTACTAGAGTTTGATATTCC
TGTTCGTGGGGATAATCGTGGCTGGTTTAAAGAAAATTTCCAAAAAGAAAAAATGTTGCCAATTGGCTTTCCAGAACGTT
TTTTTGAGGAAGGAAAACTACAAAACAACGTTTCTTTTTCACGTCAGCATGTGCTGCGTGGACTTCATGCTGAACCTTGG
GATAAATACATCTCAGTTGCTGATGATGGCAAGGTTTTAGGAGCTTGGGTTGATCTTCGTGAGGGAGAGACTTTTGGAAA
CGTCTACCAGACAGTGATTGATGCTTCAAAAGGAATGTTTGTTCCTAGAGGGGTTGCTAATGGCTTTCAAGTTCTTTCAG
AGACTGTCTCTTACAGTTATCTTGTCAATGACTACTGGGCTCTTGACTTGAAACCTAAGTATGCTTTTGTAAACTATGCT
GACCCAAGTCTTGGGATTACTTGGGAAAATCTAGCAGCTGCAGAAGTTTCTGAAGCAGATAAAAACCATCCTCTTCTTAG
TGATGTCAAACCACTGAAACCAAAAGACCTATAG

Upstream 100 bases:

>100_bases
GCATGGGCTATATCAGTAAAGAAGATGTCCATAAATTGGCGCAATCTTTAAAGAAAAACGAATACGGGCAATACTTGCTT
CGTTTGATTGGAGAAGCTTA

Downstream 100 bases:

>100_bases
GGAAACAACATACTCAGATGATTGGGATTAATCATTTGAGGTGGATATGAGGGGAGTTATTCTTCTCTACTTCAGGTAAC
AAGTAACAACTAAAAATGAT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPW
DKYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL

Sequences:

>Translated_197_residues
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPW
DKYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL
>Mature_196_residues
TETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWD
KYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYAD
PSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family

Homologues:

Organism=Escherichia coli, GI1788350, Length=186, Percent_Identity=29.0322580645161, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17550412, Length=177, Percent_Identity=32.2033898305085, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RMLC_STRP6 (Q5XCG7)

Other databases:

- EMBL:   CP000003
- RefSeq:   YP_060079.1
- HSSP:   P26394
- ProteinModelPortal:   Q5XCG7
- SMR:   Q5XCG7
- EnsemblBacteria:   EBSTRT00000038641
- GeneID:   2942431
- GenomeReviews:   CP000003_GR
- KEGG:   spa:M6_Spy0761
- GeneTree:   EBGT00050000027042
- HOGENOM:   HBG730537
- OMA:   YQIRQPQ
- ProtClustDB:   CLSK876701
- BioCyc:   SPYO286636:M6_SPY0761-MONOMER
- BRENDA:   5.1.3.13
- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR21047
- ProDom:   PD001462

Pfam domain/function: PF00908 dTDP_sugar_isom; SSF51182 RmlC_like_cupin

EC number: =5.1.3.13

Molecular weight: Translated: 22438; Mature: 22306

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: BINDING 33-33 BINDING 38-38

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKL
CCCCCCCCCHHHHHHHHCCCCEEECCEEECCCCCHHHHCCCCCCCCCCCCCHHHHHCCCC
QNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMF
CCCCHHHHHHHHHCCCCCCHHHEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCC
VPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYADPSLGITWENLAAAEVSEAD
CCCCHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
KNHPLLSDVKPLKPKDL
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEKMLPIGFPERFFEEGKL
CCCCCCCCHHHHHHHHCCCCEEECCEEECCCCCHHHHCCCCCCCCCCCCCHHHHHCCCC
QNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREGETFGNVYQTVIDASKGMF
CCCCHHHHHHHHHCCCCCCHHHEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCC
VPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYADPSLGITWENLAAAEVSEAD
CCCCHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
KNHPLLSDVKPLKPKDL
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA