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The map label for this gene is deoD

Identifier: 15674918

GI number: 15674918

Start: 741129

End: 741842

Strand: Direct

Name: deoD

Synonym: SPy_0894

Alternate gene names: 15674918

Gene position: 741129-741842 (Clockwise)

Preceding gene: 15674917

Following gene: 15674919

Centisome position: 40.01

GC content: 42.72

Gene sequence:

>714_bases
ATGTCTATCCATATTTCTGCCAAAAAAGGCGATATTGCTGATAAAATTCTTCTACCTGGAGATCCTTTGCGCGCGAAATT
TATCGCTGAAAATTTCCTAGAAGATGCAGTGTGTTTTAACGAAGTGCGTAACATGTTTGGCTACACAGGAACTTACAAAG
GGCACCGCGTTTCTGTCATGGGAACTGGTATGGGGATGCCTTCGATCTCTATCTATGCTCGTGAATTAATCGTTGATTAC
GGTGTCAAAACATTGATCCGTGTTGGTACTGCGGGTGCGATTGACCCAGAAGTTCATGTGCGTGAATTGGTGCTTGCCCA
AGCAGCAGCAACCAACTCAAATATTATCCGTAATGACTTCCCAGAATTTGATTTCCCACAAATTGCTGATTTTGGTTTAC
TTGACAAGGCTTACCATATCGCCAGAGAAATGGGAGTAACAACTCACGTTGGGAATGTGCTTTCTTCTGATGTCTTTTAC
ACTAACATGCCTGAGCGTAATATGGCTCTTGGTAAATTGGGTGTTAAAGCCATCGAAATGGAAGCAGCAGCTCTTTACTA
TTTAGCTGCTCAGCACCATGTCAAAGCCCTTGGAATCATGACGATCTCAGATAACTTGAATGATCCAACCGAAGATACTA
CAGCTGAAGAGCGCCAAACAACTTTCACTGATATGATGAAGGTCGGCTTGGAAACCTTAATTGCCAATGACTAA

Upstream 100 bases:

>100_bases
TAAGGACTTGGTCAAAAAGATAAGTTGTCTAGAAAATCAGGATTTTCTGCCAACTTCCTATTTTGCCATCGTTCTTTTAA
CGCCCTCAGTATCATAATTT

Downstream 100 bases:

>100_bases
TAATCAAACACTAGACATCCTTTTGGATGTCTATGCTTATAATCACGCCTTTAGAATTGCTAAAGCCTTGCCAAATATCC
CTAAAACTGCCCTCTATTTA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDY
GVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND

Sequences:

>Translated_237_residues
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDY
GVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND
>Mature_236_residues
SIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYG
VKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYT
NMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=50.8547008547009, Blast_Score=241, Evalue=3e-65,
Organism=Escherichia coli, GI1790265, Length=209, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_STRPB (Q1JC85)

Other databases:

- EMBL:   CP000261
- RefSeq:   YP_600367.1
- ProteinModelPortal:   Q1JC85
- SMR:   Q1JC85
- STRING:   Q1JC85
- EnsemblBacteria:   EBSTRT00000044398
- GeneID:   4066096
- GenomeReviews:   CP000261_GR
- KEGG:   spj:MGAS2096_Spy0771
- eggNOG:   COG0813
- GeneTree:   EBGT00050000027156
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- ProtClustDB:   PRK05819
- BioCyc:   SPYO370553:MGAS2096_SPY0771-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 26020; Mature: 25889

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVM
CEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCC
PEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNMPERNMALGKLGVKAIEM
CCCCCCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCHHHHHHCHHHHHH
EAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND
HHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVM
EEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCC
PEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNMPERNMALGKLGVKAIEM
CCCCCCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCHHHHHHCHHHHHH
EAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKVGLETLIAND
HHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA