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The map label for this gene is fruR [H]

Identifier: 15674886

GI number: 15674886

Start: 704676

End: 705389

Strand: Direct

Name: fruR [H]

Synonym: SPy_0853

Alternate gene names: 15674886

Gene position: 704676-705389 (Clockwise)

Preceding gene: 15674885

Following gene: 15674887

Centisome position: 38.04

GC content: 36.13

Gene sequence:

>714_bases
ATGGCAAAGATCACTGAAGAAAACTATGTTTCTTTAGAGGATTTAATGCAATTACTCAACTCCTCTGAGTCTACTATCCG
TAGAGATCTAGGAGAGTTGGAGCAAGAAGGACGGCTACATCGTGTTCATGGAGGTGCTGAACTTTTTCACTCTTTACAAG
AGGAACTTTCGAACCAAGAAAAGTCTGTCAAAAACAGTCATATTAAAAAAGCTATTGCGCAAAGAGCCTCTCAGCTTATC
TATGACAACGATGTGATCTTTATTGATGCTGGGACAACGACTGAATTTTTATTACCTTTTTTACAAGCTAAAAATTTAAC
TGTAGTTACTAATTCTATTCATCATGCTGCTAGATTAGTTGAACTCTCTATTGAGACGATTATTGTAGGGGGTTATGTCA
AACAAACGACCGATGCCAGTATTGGTAACGTAGCTTTGGAACAGATTAGGCAGATGAATTTTGACAAGGCATTTCTTGGA
ATGAATGGTGTTGATGATTCTTACCTGACGACTCCTGATATGGAAGAAGCAGTTATTAAAAAAGCGGTTCTGTCAAATGC
AAAATTAGCTTACATTTTAGTAGATGGCACTAAAATTGGTCAGGTATCGTTTGTAAAAGTAGCTCCTATTAATGATGTGA
CTATTATTACATTAGGAGGATCAGCAAGTATTCTTAAACAAATAAAGGAAAAGGCAAAGGTGATTGAATTATGA

Upstream 100 bases:

>100_bases
AAGATTATGCTTGACTTTTAGTTATAAAATAGTATAATAATTGTAAACGATTTCAGTTAGGGGTGGTTCTATCTTAAAAT
CAAAACGAAAACAATTAATC

Downstream 100 bases:

>100_bases
TTTATACCGTGACCTTAAACCCTTCTATTGACTTTATTGTCAGAATTGACCAAATAAATCTTGGGTCAGTGAATCGCATG
GCGAGTGATGATAAGTTTGC

Product: putative transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLI
YDNDVIFIDAGTTTEFLLPFLQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL

Sequences:

>Translated_237_residues
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLI
YDNDVIFIDAGTTTEFLLPFLQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
>Mature_236_residues
AKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLIY
DNDVIFIDAGTTTEFLLPFLQAKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLGM
NGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL

Specific function: Repressor Of The Gat Operon For Galacticol Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510968, Length=211, Percent_Identity=32.7014218009479, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1789059, Length=226, Percent_Identity=31.858407079646, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789829, Length=213, Percent_Identity=32.3943661971831, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787540, Length=210, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789519, Length=220, Percent_Identity=28.1818181818182, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788069, Length=216, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082344, Length=219, Percent_Identity=27.8538812785388, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789170, Length=216, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790753, Length=234, Percent_Identity=25.2136752136752, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790635, Length=228, Percent_Identity=24.1228070175439, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26109; Mature: 25978

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFHSLQEELSNQE
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
KSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQAKNLTVVTNSIHHAARLV
HHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHCCCEEEEEHHHHHHHHHH
ELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLGMNGVDDSYLTTPDMEEAVIK
HHHHEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHH
KAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
HHHHCCCCEEEEEEECCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHGGAELFHSLQEELSNQE
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
KSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQAKNLTVVTNSIHHAARLV
HHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHCCCEEEEEHHHHHHHHHH
ELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLGMNGVDDSYLTTPDMEEAVIK
HHHHEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHH
KAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITLGGSASILKQIKEKAKVIEL
HHHHCCCCEEEEEEECCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]