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The map label for this gene is atpB

Identifier: 15674803

GI number: 15674803

Start: 614865

End: 615581

Strand: Direct

Name: atpB

Synonym: SPy_0755

Alternate gene names: 15674803

Gene position: 614865-615581 (Clockwise)

Preceding gene: 15674802

Following gene: 15674804

Centisome position: 33.19

GC content: 38.91

Gene sequence:

>717_bases
ATGGAAGAAGCTAAAATACCTATGCTGAAGCTTGGTCCAATAACCTTTAATTTGACCCTACTTGCTGTTTGTATTGTCAC
AATTGCGATTGTCTTTGCCTTTGTTTTTTGGGCAAGTCGCCAAATGAAATTGAAACCAGAAGGGAAGCAAACTGCTTTAG
AATATTTAATCAGTTTTGTGGATGGTATTGGAGAAGAGCACTTAGATCATAATCTACAAAAATCTTATTCGCTGTTACTC
TTTACCATTTTTCTCTTTGTGGCTGTCGCTAATAATTTAGGGTTATTTACTAAGTTAGAGACAGTTAATGGCTATAACCT
ATGGACCTCGCCAACAGCCAATCTGGCTTTTGACCTTGCTCTATCTCTTTTTATTACCTTAATGGTACACATTGAAGGGG
TTAGACGGCGTGGCTTGGTTGCCCATTTGAAACGTTTGGCTACACCGTGGCCAATGACTCCGATGAATTTATTAGAAGAG
TTCACAAATTTCTTATCACTTGCCATTAGGTTATTCGGTAATATCTTTGCCGGGGAAGTTGTTACAGGTTTGATTGTTCA
ACTGGCCAATTATCGAGTTTATTGGTGGCCGATTGCTTTCCTAGTCAATATGGCGTGGACAGCCTTTTCAGTCTTTATTT
CCTGCATACAGGCTTTCGTTTTCACAAAACTGACAGCGACCTATCTAGGAAAGAAAGTCAATGAATCAGAAGAATAA

Upstream 100 bases:

>100_bases
TTGGGTGTTGCCTTTATCGAAGGTACTTTCTTCGTTACCCTTGTTATGGCCTTCATTCTTAAATAACAGCCTATTTTATA
ATAGAAAAGGAGGGTGTTAG

Downstream 100 bases:

>100_bases
GGAAGGAGAACAAACGAATGTCAATCACATTTGGTGAACTCGTTGGGAATTTTATTCTAGTAACAGGTTCTGTAATCGTC
TTGTTACTCTTGATCAAAAA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKLKPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLL
FTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE

Sequences:

>Translated_238_residues
MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKLKPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLL
FTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE
>Mature_238_residues
MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKLKPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLL
FTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=205, Percent_Identity=30.7317073170732, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_STRP1 (Q9A0J2)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268977.1
- RefSeq:   YP_281939.1
- ProteinModelPortal:   Q9A0J2
- SMR:   Q9A0J2
- EnsemblBacteria:   EBSTRT00000000755
- EnsemblBacteria:   EBSTRT00000028596
- GeneID:   3572322
- GeneID:   900934
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0755
- KEGG:   spz:M5005_Spy_0576
- GeneTree:   EBGT00050000028075
- HOGENOM:   HBG734175
- OMA:   NIFAGEM
- ProtClustDB:   PRK05815
- BioCyc:   SPYO160490:SPY0755-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0576-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 26924; Mature: 26924

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc7a2124)-; HASH(0xccfd3d0)-; HASH(0xd21f720)-; HASH(0xd219398)-; HASH(0xc34923c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKLKPEGKQTALEYLISFV
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
DGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCHHHHHHHH
LSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEV
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MEEAKIPMLKLGPITFNLTLLAVCIVTIAIVFAFVFWASRQMKLKPEGKQTALEYLISFV
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
DGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETVNGYNLWTSPTANLAFDLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCHHHHHHHH
LSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEV
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQAFVFTKLTATYLGKKVNESEE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296