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The map label for this gene is aspC [H]

Identifier: 15674718

GI number: 15674718

Start: 523708

End: 524901

Strand: Direct

Name: aspC [H]

Synonym: SPy_0650

Alternate gene names: 15674718

Gene position: 523708-524901 (Clockwise)

Preceding gene: 15674717

Following gene: 15674719

Centisome position: 28.27

GC content: 42.38

Gene sequence:

>1194_bases
ATGCCCAAACTATCAAAGCGAGTTTTAGAAATGAAAGAGAGTGTTACTCTGGCTGCAGGTGCTAGAGCTAAGGCTTTGAA
AGCGCAGGGCCGCGATGTACTGAATTTAACTTTAGGAGAACCAGATTTTTTTACACCTAAGCACATTCAAGACAAGGCGA
TTGAATCTATTCAAAATGGTACGGCTAGCTTTTATACAAATGCTTCTGGGCTTCCAGAATTAAAAGCTGCGATTGCCACA
TACCTGAAAAATCAGTATGGGTATCACTTGTCTCCTGATCAGATTGTGGCAGGAACAGGTGCCAAGTTCATCCTTTATGC
CTTTTTTATGGCTGTTTTAAATCCTGGTGACCAAGTTCTCATTCCAACACCATATTGGGTATCTTATTCTGACCAAGTAA
AAATGGCAGAAGGTCAGCCGATCTTCGTTCAAGGACTAGAAGAAAATCAATTCAAGGTAACTGTTGACCAGCTGGAAAGA
GCAAGGACAAGTAAGACTAAAGTTGTCCTTATCAATTCTCCTTCCAATCCAACAGGCATGATTTATGGTGCTGAGGAATT
AAGGGCCATTGGAGAATGGGCGGTGCACAACGATATTCTTATTCTGGCAGATGATATTTACGGGTCCTTAGTCTATAACG
GCAATCAGTTTGTTCCTATTTCAACACTCTCAGAAGCGATTCGGCGTCAAACCATTACGGTCAATGGCGTGGCTAAAAGT
TATGCCATGACAGGCTGGCGGGTTGGTTTTGCAGCAGGTGAACCAGAGATCATTTCGGCAATGAGTAAGATCATCGGGCA
GACTACCTCTAACCTGACAACCGTTTCACAATATGCTGCTATCGAGGCTTTCTGTGGTAGTCAGTCATCACTTGAAGAGA
TGCGATTAGCATTTGAAGAGCGCCTTAATATCACTTATCCATTGTTGTGTCAGGTCCCTGGGTTTGAGGTTGTTAAACCA
CAAGGAGCTTTTTACTTCTTTCCAAACGTTAAGAAAGCCATGGAAATGACAGGTTTTTCCGATGTGACAAGCTTTGCTAA
TGCTATTTTAGAGGAAGTCGGATTAGCTGTTGTGAGTGGAGCAGGCTTTGGCGCACCGGAAAATGTTCGTCTGAGTTATG
CTACAGATATCGAAACCCTTAAAGAAGCTGTTCGTAGACTGCATGTCTTTATGGAAAGTAATGAAATTAATTAA

Upstream 100 bases:

>100_bases
AGTAGCGAGTATTGGTAAAACTGAAACCGTAGATTATGAAAAAATGATCTGTTGAGCATTAATTAATCTGAAGATAAGAA
GTCGATAAAAAGGAGATACG

Downstream 100 bases:

>100_bases
ATAAAAATAGAGAGAAACTTATGTCAAAAAAACTTATTTCAATTGTTGATGTTAAAGATTATGTTGGTCAAGAAGTTACT
ATTGGTGCTTGGGTTGCTAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIAT
YLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKP
QGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN

Sequences:

>Translated_397_residues
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIAT
YLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKP
QGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
>Mature_396_residues
PKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATY
LKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERA
RTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKSY
AMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQ
GAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=25.6857855361596, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=25.6857855361596, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=28.125, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI56713256, Length=315, Percent_Identity=27.6190476190476, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=23.6979166666667, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=23.2911392405063, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19263340, Length=395, Percent_Identity=23.2911392405063, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI215599424, Length=395, Percent_Identity=23.2911392405063, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4885351, Length=383, Percent_Identity=24.5430809399478, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=373, Percent_Identity=26.0053619302949, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=27.012987012987, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=24.3169398907104, Blast_Score=118, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=27.4151436031332, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=433, Percent_Identity=27.2517321016166, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=294, Percent_Identity=29.9319727891156, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=294, Percent_Identity=29.9319727891156, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=405, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=24.8101265822785, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=344, Percent_Identity=23.546511627907, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=345, Percent_Identity=23.1884057971014, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573069, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24646114, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573067, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573065, Length=262, Percent_Identity=29.7709923664122, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.9583333333333, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551451, Length=408, Percent_Identity=24.5098039215686, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24641770, Length=408, Percent_Identity=24.5098039215686, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641760, Length=408, Percent_Identity=24.5098039215686, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641768, Length=408, Percent_Identity=24.5098039215686, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641766, Length=408, Percent_Identity=24.5098039215686, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641764, Length=408, Percent_Identity=24.5098039215686, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43461; Mature: 43330

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNG
CCCHHHHHHHHHHHEEEECCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC
TASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVL
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEE
IPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERARTSKTKVVLINSPSNPTGM
ECCCCEECCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEE
IYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
EECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEHHHHHHHHHHCEEEEECHHHH
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEE
HHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSG
HCCCCEEEEEECCCCEEECCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
AGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFFTPKHIQDKAIESIQNG
CCHHHHHHHHHHHEEEECCCHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCC
TASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAKFILYAFFMAVLNPGDQVL
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEE
IPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLERARTSKTKVVLINSPSNPTGM
ECCCCEECCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEE
IYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFVPISTLSEAIRRQTITVNGVAKS
EECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEHHHHHHHHHHCEEEEECHHHH
YAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVSQYAAIEAFCGSQSSLEEMRLAFEE
HHHCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAMEMTGFSDVTSFANAILEEVGLAVVSG
HCCCCEEEEEECCCCEEECCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
AGFGAPENVRLSYATDIETLKEAVRRLHVFMESNEIN
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]