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The map label for this gene is tnpA [H]

Identifier: 15674656

GI number: 15674656

Start: 455717

End: 456754

Strand: Reverse

Name: tnpA [H]

Synonym: SPy_0565

Alternate gene names: 15674656

Gene position: 456754-455717 (Counterclockwise)

Preceding gene: 15674660

Following gene: 15674647

Centisome position: 24.66

GC content: 35.45

Gene sequence:

>1038_bases
ATGTCAACAGTTAAACGCTATGATGAAGAATTCAAACAATCTCTTGTTAACCTTTATCAAACTGGAAAAACTCGGTCTGA
ACTCTGTAAAGACTATGGGGTATCCGCTTCTGCGCTTGCAAAATGGATCAAACAGTATTCCCAAGTCAAACTCGAAGATA
ATTCTGTACTTACTGCCAAGCAAATACAAGAGCTACAAAAACGTAATGCGCAGCTTGAAGAGGAGAACCTTATCCTAAAA
AAAAGCAAGTGCCATATTCATGCAAAACTTAAAGTAAGACTCCTCGCTGTTTATCGGTTACGCTTTGAACACGTCACAAC
AACCTTGTATCGTGTTTTACGTGTCAATCGCTCCACTTACTATAAATTTCTAAAACATAAGCCCTCAAAAAGAGAATTGG
ATAATCAAATTTATAGAAAACAAATACTTGAGATTTATACCAAAGCAAACAAAAGACTTGGTGTGAAGTCTATCAAAGTC
ATTCTTCAAAGAGACTACGACACAAAAATCTCTGAAGGAAGAATTTACCGTCTAATGAAGAATATGGCGCTCCCTAAAAT
GGCTACCGTTAAGCCAAAAACAGCTCTTAAAAGGACTCAAAAAACGTATCCTCAAAACTTACTCAACCAGAAATTTAATC
CTGACAAACCTAATCAAGTATGGTCTACTGACTTCACCTATATTTCTATTGGATATAAGAAATATGTCTATCTCTGCGCA
ATACTTGATCTCTATTCTAGAAAATGTATTGCTTGGAAACTGAGTCACCGTATGGATGCAAAGTTAGCATGTGACACTCT
AGAATTAGCTCTTAATAAAAGAAAGATTGAAGGAACACTTCTCTTTCATTCCGACCAAGGGTCACAATTTAAGGCCAGGG
AATTGAGAAAAATAATTGATGACAACACTATCATGCATTCTTTTTCTAAACCTGGATATCCTTATGATAATGCCGTAACT
GAAGCATTTTTCAAGTATTTAAAGCATAGACAAATCAACCAAAAAAAGTATCAAACAGGTTCAATTAGACTGCTTTGA

Upstream 100 bases:

>100_bases
TTTATTTTTATAAATGACCACTGGATGTATACTATAAAAGTAGACAAAACTTTGTGTGTTACAATCTGTTTTAAAAGACA
CAAAAACGAAAGGACAGCCT

Downstream 100 bases:

>100_bases
ATACATTGAGAATTTTTATAACAATTACAACCCACATACGGCTAATCTAGGACTAACCCCTAATCAGAAAGAAGAAAATT
AGTTTAACGTAATAAAATAA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSTVKRYDEEFKQSLVNLYQTGKTRSELCKDYGVSASALAKWIKQYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLILK
KSKCHIHAKLKVRLLAVYRLRFEHVTTTLYRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPNQVWSTDFTYISIGYKKYVYLCA
ILDLYSRKCIAWKLSHRMDAKLACDTLELALNKRKIEGTLLFHSDQGSQFKARELRKIIDDNTIMHSFSKPGYPYDNAVT
EAFFKYLKHRQINQKKYQTGSIRLL

Sequences:

>Translated_345_residues
MSTVKRYDEEFKQSLVNLYQTGKTRSELCKDYGVSASALAKWIKQYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLILK
KSKCHIHAKLKVRLLAVYRLRFEHVTTTLYRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPNQVWSTDFTYISIGYKKYVYLCA
ILDLYSRKCIAWKLSHRMDAKLACDTLELALNKRKIEGTLLFHSDQGSQFKARELRKIIDDNTIMHSFSKPGYPYDNAVT
EAFFKYLKHRQINQKKYQTGSIRLL
>Mature_344_residues
STVKRYDEEFKQSLVNLYQTGKTRSELCKDYGVSASALAKWIKQYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLILKK
SKCHIHAKLKVRLLAVYRLRFEHVTTTLYRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKVI
LQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPNQVWSTDFTYISIGYKKYVYLCAI
LDLYSRKCIAWKLSHRMDAKLACDTLELALNKRKIEGTLLFHSDQGSQFKARELRKIIDDNTIMHSFSKPGYPYDNAVTE
AFFKYLKHRQINQKKYQTGSIRLL

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=220, Percent_Identity=30.9090909090909, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788405, Length=244, Percent_Identity=29.5081967213115, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787263, Length=244, Percent_Identity=29.5081967213115, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786753, Length=244, Percent_Identity=29.5081967213115, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786570, Length=244, Percent_Identity=29.5081967213115, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786490, Length=244, Percent_Identity=29.5081967213115, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789981, Length=222, Percent_Identity=31.0810810810811, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 40789; Mature: 40658

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVKRYDEEFKQSLVNLYQTGKTRSELCKDYGVSASALAKWIKQYSQVKLEDNSVLTAK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCEECHH
QIQELQKRNAQLEEENLILKKSKCHIHAKLKVRLLAVYRLRFEHVTTTLYRVLRVNRSTY
HHHHHHHHCCCCCHHCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
YKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKVILQRDYDTKISEGRIYRLMK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
NMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPNQVWSTDFTYISIGYKKYVYLCA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
ILDLYSRKCIAWKLSHRMDAKLACDTLELALNKRKIEGTLLFHSDQGSQFKARELRKIID
HHHHHCCHHHEEEHHHCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHC
DNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINQKKYQTGSIRLL
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure 
STVKRYDEEFKQSLVNLYQTGKTRSELCKDYGVSASALAKWIKQYSQVKLEDNSVLTAK
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCEECHH
QIQELQKRNAQLEEENLILKKSKCHIHAKLKVRLLAVYRLRFEHVTTTLYRVLRVNRSTY
HHHHHHHHCCCCCHHCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
YKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKVILQRDYDTKISEGRIYRLMK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
NMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPNQVWSTDFTYISIGYKKYVYLCA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
ILDLYSRKCIAWKLSHRMDAKLACDTLELALNKRKIEGTLLFHSDQGSQFKARELRKIID
HHHHHCCHHHEEEHHHCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHC
DNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINQKKYQTGSIRLL
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]