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The map label for this gene is bacD [H]

Identifier: 15674655

GI number: 15674655

Start: 451805

End: 453088

Strand: Direct

Name: bacD [H]

Synonym: SPy_0560

Alternate gene names: 15674655

Gene position: 451805-453088 (Clockwise)

Preceding gene: 15674654

Following gene: 15674657

Centisome position: 24.39

GC content: 29.98

Gene sequence:

>1284_bases
ATGGGATTGATTATTTACCATAAAGGAGGAAGAAAAATGAAAAAGAATATTTTAATTGTAGGTGGAGGTCCAGAGATAAC
TATATGTTATGATTTAATTAACAATAGTACGGAGTATAATTTCTTTTCAGTATCAGAAATTCCTACGATGTATCCAGAGT
TGTTTGTAGAAACAATTGAAACCAGCTTTAGAAATTTTGGAAAGACGATTGAACAAATTAAAGAGCTCAAATATTCTATT
GATGCTGTTGCTTGTTGGGATGAAGCTTTAACGCATATAGCTGATGATATTTCAAAAGAATTAGGATTGAACCCTATTTC
ATCGCTAGATTCTCAATCATTCAGGTTTAAAGATCGAATGAGAATGGTATGTGAAGCTGGTGGACTAAAAATGCCCAAAT
ATAAAATTATCAATCAATTTTCAGATACAAATAAAATAATCAATTGGAAATATCCATTAATAGTGAAACCAACCTCTTTT
TTAGCAAGTATAGGAGTGAAAAAAGTTTATAATTTTTCAGAATTACAACAAGCAGTTTCTCAAATGCTTAATGTAAAATT
TCCGGTTTACATAGCTTCAGGGGTATATGAATTGGGGGAATTATATAATTTAGAACCTAGAGTTTTGGTGGAAGAGTTTA
TTGATGGAGAAGAATATAGCTTAGAGAGCGTGGTAAGAAATGGAATCTATACACCTCTAGGGATAACTAAAAAAATAGTG
GATGAAAAATTATTTATGGATGAAATAGGCCATATTTTCCCTTCAAATTTAAACAAAGAAGAAAAAAGTAGAGTATATTC
TTGGGCAGAAAAATTACATCAAATTTTGCAATTAAATCATATTACGACTCATACAGAATTTAGAATTGGAAGAAATGGAG
ATATTATTTTAATAGAAATTGGAGCAAGAATCGGTGGAGATTGTATTCCAAACTTAATGAAAAACAGCTTTATAGTCAAG
GGATTTGATTTTTATAATACTTATTTAAAAGCTAGACTAGGTTTACAAGAAGAGTTAAATACAGACACTAATAAGTTTTC
AGGAATTGTATTTTTCAGACTCAATCCAGAGAATTACGGAAAAATATTTAATGGAGTGAGTTACGATGCACCTAAAACTT
CACTAATATTTGAAGAAAAGATATATAAAAAGGAAGGAACTGTATTGCCAAATCCGATTAATTGGAGTAATGAGAGAGTA
GGATATGTCTGTTTGGAAAACAAGGAATACGCTGTGCTAGAAAAGGAGATGAAAGAAATATTAAAATCATTGTCAATAGA
GTAA

Upstream 100 bases:

>100_bases
CCTATGAAATCTTCAGGATTTGGTTTAGGAGTAGAGCGTTTAATAGCGTGGATATTGAAGTGCGATGATGTTCGAAAAGT
TCAATTAATCAGTAGAGAAA

Downstream 100 bases:

>100_bases
ATAGTGAAAGAAACATCAAATCTATAGGTATTTGTTCACCCTCCTATCCGGGGACATTTCATTATCAGAAACGATATAAG
AGAGGAGTAGAATTTTTACA

Product: hypothetical protein

Products: NA

Alternate protein names: Bacilysin synthetase; L-amino acid ligase [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MGLIIYHKGGRKMKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFVETIETSFRNFGKTIEQIKELKYSI
DAVACWDEALTHIADDISKELGLNPISSLDSQSFRFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSF
LASIGVKKVYNFSELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIYTPLGITKKIV
DEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRNGDIILIEIGARIGGDCIPNLMKNSFIVK
GFDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYGKIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERV
GYVCLENKEYAVLEKEMKEILKSLSIE

Sequences:

>Translated_427_residues
MGLIIYHKGGRKMKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFVETIETSFRNFGKTIEQIKELKYSI
DAVACWDEALTHIADDISKELGLNPISSLDSQSFRFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSF
LASIGVKKVYNFSELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIYTPLGITKKIV
DEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRNGDIILIEIGARIGGDCIPNLMKNSFIVK
GFDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYGKIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERV
GYVCLENKEYAVLEKEMKEILKSLSIE
>Mature_426_residues
GLIIYHKGGRKMKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFVETIETSFRNFGKTIEQIKELKYSID
AVACWDEALTHIADDISKELGLNPISSLDSQSFRFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFL
ASIGVKKVYNFSELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIYTPLGITKKIVD
EKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRNGDIILIEIGARIGGDCIPNLMKNSFIVKG
FDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYGKIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERVG
YVCLENKEYAVLEKEMKEILKSLSIE

Specific function: Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. Probably catalyzes the ligation of L-alanine and L-anticapsin to produce the final bacilysin antibiotic [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011095 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C [H]

EC number: =6.3.2.28 [H]

Molecular weight: Translated: 48985; Mature: 48854

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50975 ATP_GRASP ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIIYHKGGRKMKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFVETIE
CCEEEEECCCCEEECCEEEECCCCCEEEEEEECCCCCCCCEEEHHHCCHHHHHHHHHHHH
TSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSFRFKDRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHH
RMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNFSELQQAVS
HHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCEEECCHHHHHHHHHHHHCCHHHHHHHHH
QMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIYTPLGITKKIV
HHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHH
DEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRNGDIILIEI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCEEEECCCCCEEEEEE
GARIGGDCIPNLMKNSFIVKGFDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYG
CCCCCCHHHHHHHHCCEEEECHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEECCHHHH
KIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERVGYVCLENKEYAVLEKEMKEI
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LKSLSIE
HHHHCCC
>Mature Secondary Structure 
GLIIYHKGGRKMKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFVETIE
CEEEEECCCCEEECCEEEECCCCCEEEEEEECCCCCCCCEEEHHHCCHHHHHHHHHHHH
TSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSFRFKDRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHH
RMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNFSELQQAVS
HHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCEEECCHHHHHHHHHHHHCCHHHHHHHHH
QMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIYTPLGITKKIV
HHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHH
DEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRNGDIILIEI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCEEEECCCCCEEEEEE
GARIGGDCIPNLMKNSFIVKGFDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYG
CCCCCCHHHHHHHHCCEEEECHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEECCHHHH
KIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERVGYVCLENKEYAVLEKEMKEI
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LKSLSIE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA