Click here to switch to the map view.

The map label for this gene is frr [H]

Identifier: 15674582

GI number: 15674582

Start: 380596

End: 381153

Strand: Direct

Name: frr [H]

Synonym: SPy_0463

Alternate gene names: 15674582

Gene position: 380596-381153 (Clockwise)

Preceding gene: 15674581

Following gene: 15674583

Centisome position: 20.55

GC content: 39.96

Gene sequence:

>558_bases
ATGGCAAATGCAATTATTGAAACTGCAAAAGAACGTTTTGCACAATCCCATCAGTCTTTATCACGTGAATATGCCAGCAT
TCGTGCGGGTCGTGCCAACGCTAGTCTTTTAGACCGTATCCAAGTTGATTATTACGGGGCACCGACACCATTAAATCAAT
TGGCTTCAATCACTGTACCAGAAGCGCGTGTCTTATTGATCTCGCCTTTTGATAAATCTTCTATCAAAGATATCGAGCGC
GCTCTTAACGCATCAGATTTAGGCATTACACCTGCTAACGATGGCTCTGTCATTCGTTTGGTTATTCCAGCTTTGACCGA
AGAAACACGTAAAGAATTAGCCAAAGAAGTGAAAAAAGTTGGTGAAAATGCTAAAATTGCAATCCGTAATATCCGCCGCG
ATGCTATGGATGATGCTAAAAAGCAAGAAAAAGCAAAAGAAATCACTGAAGATGAGTTAAAAACACTTGAGAAAGATATC
CAAAAAGCAACCGATGATGCTATCAAAGAAATTGACCGCATGACGGCTGAAAAAGAAAAAGAATTGCTCTCAGTGTAA

Upstream 100 bases:

>100_bases
GCTGGCAATATTCAACGTGTTGTCTTTGGAGAACATATTGGAACTACTGTATCAAATAAAGTTTGTGACTAAAAGTTAGA
AAAGAAAGAGAGTAATTATC

Downstream 100 bases:

>100_bases
CAGGATTCCTACGAAAAATAGACGACTATAGACACAAAAAGATAGGTGACCATTTCAGAAGCGTTTGGTTTTGATTTGTC
CCTATCTTTTTAAAGAAAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
QKATDDAIKEIDRMTAEKEKELLSV

Sequences:

>Translated_185_residues
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
QKATDDAIKEIDRMTAEKEKELLSV
>Mature_184_residues
ANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERA
LNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQ
KATDDAIKEIDRMTAEKEKELLSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI291042689, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20270317, Length=156, Percent_Identity=31.4102564102564, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=47.5409836065574, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20573; Mature: 20441

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
EARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLSV
HHHCC
>Mature Secondary Structure 
ANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
EARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLSV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA