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The map label for this gene is mtsA

Identifier: 15674573

GI number: 15674573

Start: 371477

End: 372409

Strand: Direct

Name: mtsA

Synonym: SPy_0453

Alternate gene names: 15674573

Gene position: 371477-372409 (Clockwise)

Preceding gene: 15674571

Following gene: 15674574

Centisome position: 20.05

GC content: 35.8

Gene sequence:

>933_bases
ATGGGAAAGAGAATGAGCCTCATTTTGGGTGCTTTTTTATCTGTTTTTCTTTTAGTAGCTTGTTCGTCAACTGGCACTAA
AACTGCTAAGAGTGATAAATTAAAAGTCGTGGCAACCAATTCAATTATTGCCGACATGACAAAAGCTATTGCTGGTGATA
AAATCGATCTGCACAGCATTGTGCCAATCGGTCAAGACCCTCATGAGTACGAACCATTACCAGAAGATGTTGAAAAAACA
AGTAATGCTGATGTGATTTTCTATAATGGTATCAATCTAGAAGATGGCGGGCAAGCTTGGTTCACCAAACTAGTGAAAAA
TGCTCAAAAAACGAAAAACAAAGATTACTTTGCCGTGTCTGATGGCATTGATGTGATTTACTTGGAAGGTGCAAGCGAAA
AAGGAAAAGAAGATCCACATGCTTGGTTAAATCTCGAAAACGGAATCATTTATTCAAAAAACATTGCCAAACAATTGATT
GCAAAGGATCCTAAAAACAAAGAAACTTATGAAAAGAACCTAAAAGCTTATGTGGCTAAATTGGAAAAACTAGACAAAGA
AGCCAAATCAAAATTTGATGCTATTGCAGAAAATAAAAAATTGATTGTGACTAGTGAAGGCTGCTTCAAGTACTTTTCAA
AAGCTTACGGTGTCCCATCTGCTTATATCTGGGAAATTAACACCGAAGAAGAAGGAACACCAGATCAAATTTCATCATTG
ATTGAAAAACTAAAAGTCATCAAGCCATCTGCGCTTTTTGTAGAGTCAAGTGTCGATAGACGCCCTATGGAAACTGTTTC
TAAAGATAGTGGTATTCCTATTTATTCTGAGATCTTTACAGATTCAATTGCTAAAAAAGGTAAACCTGGCGATAGTTATT
ATGCTATGATGAAATGGAACCTTGACAAAATTTCTGAAGGTCTAGCAAAATAA

Upstream 100 bases:

>100_bases
TTTTAGGAAAAAGCTTGACAAAAAGCCTAAAAGAGGATATCCTTATAGCATAATTAACTAAACTTAATTAAATAAATAAT
ATATCCTAAGGAGAGAAATG

Downstream 100 bases:

>100_bases
GATAACAATAAAGCACAGCGATTTTAGTGTTGTGCTTTGTTTTATTTATGTAAAGGAGACAAAATGATTACAACTAACAA
TCTTTGTGTGACCTACGATG

Product: ABC transporter metal binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
IEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

Sequences:

>Translated_310_residues
MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
IEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK
>Mature_309_residues
GKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTS
NADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIA
KDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSLI
EKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

Specific function: Part of an ATP-driven transport system for a metal; this protein has affinity for Zn(2+), Fe(3+) and Cu(2+)

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTSA_STRP1 (P0A4G4)

Other databases:

- EMBL:   AF180520
- EMBL:   AF180521
- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268747.1
- RefSeq:   YP_281731.1
- PDB:   3HH8
- PDBsum:   3HH8
- ProteinModelPortal:   P0A4G4
- SMR:   P0A4G4
- EnsemblBacteria:   EBSTRT00000000120
- EnsemblBacteria:   EBSTRT00000028907
- GeneID:   3572540
- GeneID:   900696
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0453
- KEGG:   spz:M5005_Spy_0368
- GeneTree:   EBGT00050000027213
- HOGENOM:   HBG731008
- OMA:   IADMTKN
- ProtClustDB:   CLSK876868
- BioCyc:   SPYO160490:SPY0453-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0368-MONOMER
- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128
- PRINTS:   PR00691
- PRINTS:   PR00690

Pfam domain/function: PF01297 SBP_bac_9

EC number: NA

Molecular weight: Translated: 34359; Mature: 34227

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHEE
VPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVS
CCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
DGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAK
CCCEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
HHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
IEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWN
HHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEC
LDKISEGLAK
HHHHHHHHCC
>Mature Secondary Structure 
GKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCHHEE
VPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVS
CCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
DGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAK
CCCEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
HHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
IEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWN
HHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEC
LDKISEGLAK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10564500; 11296296