| Definition | Streptococcus pyogenes M1 GAS chromosome, complete genome. |
|---|---|
| Accession | NC_002737 |
| Length | 1,852,441 |
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The map label for this gene is prtS [H]
Identifier: 15674549
GI number: 15674549
Start: 344120
End: 349063
Strand: Direct
Name: prtS [H]
Synonym: SPy_0416
Alternate gene names: 15674549
Gene position: 344120-349063 (Clockwise)
Preceding gene: 15674548
Following gene: 15674550
Centisome position: 18.58
GC content: 41.36
Gene sequence:
>4944_bases GTGGAGAAAAAGCAACGTTTTTCCCTTAGAAAATACAAATCAGGAACGTTTTCGGTCTTAATAGGAAGCGTTTTCTTGGT GATGACAACAACAGTAGCAGCAGATGAGCTAAGCACAATGAGCGAACCAACAATCACGAATCACGCTCAACAACAAGCGC AACATCTCACCAATACAGAGTTGAGCTCAGCTGAATCAAAATCTCAAGACACATCACAAATCACTCTCAAGACAAATCGT GAAAAAGAGCAATCACAAGATCTAGTCTCTGAGCCAACCACAACTGAGCTAGCTGACACAGATGCAGCATCAATGGCTAA TACAGGTTCTGATGCGACTCAAAAAAGCGCTTCTTTACCGCCAGTCAATACAGATGTTCACGATTGGGTAAAAACCAAAG GAGCTTGGGACAAGGGATACAAAGGACAAGGCAAGGTTGTCGCAGTTATTGACACAGGGATCGATCCGGCCCATCAAAGC ATGCGCATCAGTGATGTATCAACTGCTAAAGTAAAATCAAAAGAAGACATGCTAGCACGCCAAAAAGCCGCCGGTATTAA TTATGGGAGTTGGATAAATGATAAAGTTGTTTTTGCACATAATTATGTGGAAAATAGCGATAATATCAAAGAAAATCAAT TCGAGGATTTTGATGAGGACTGGGAAAACTTTGAGTTTGATGCAGAGGCAGAGCCAAAAGCCATCAAAAAACACAAGATC TATCGTCCCCAATCAACCCAGGCACCGAAAGAAACTGTTATCAAAACAGAAGAAACAGATGGTTCACATGATATTGACTG GACACAAACAGACGATGACACCAAATACGAGTCACACGGTATGCATGTGACAGGTATTGTAGCCGGTAATAGCAAAGAAG CCGCTGCTACTGGAGAACGCTTTTTAGGAATTGCACCAGAGGCCCAAGTCATGTTCATGCGTGTTTTTGCCAACGACATC ATGGGATCAGCTGAATCACTCTTTATCAAAGCTATCGAAGATGCCGTGGCTTTAGGAGCAGATGTGATCAACCTGAGTCT TGGAACCGCTAATGGGGCACAGCTTAGTGGCAGCAAGCCTCTAATGGAAGCAATTGAAAAAGCTAAAAAAGCCGGTGTAT CAGTTGTTGTAGCAGCAGGAAATGAGCGCGTCTATGGATCTGACCATGATGATCCATTGGCGACAAATCCAGACTATGGT TTGGTCGGTTCTCCCTCAACAGGTCGAACACCAACATCAGTGGCAGCTATAAACAGTAAGTGGGTGATTCAACGTCTAAT GACGGTCAAAGAATTAGAAAACCGTGCCGATTTAAACCATGGTAAAGCCATCTATTCAGAGTCTGTCGACTTTAAAGACA TAAAAGATAGCCTAGGTTATGATAAATCGCATCAATTTGCTTATGTCAAAGAGTCAACTGATGCGGGTTATAACGCACAA GACGTTAAAGGTAAAATTGCTTTAATTGAACGTGATCCCAATAAAACCTATGACGAAATGATTGCTTTGGCTAAGAAACA TGGAGCTCTGGGAGTACTTATTTTTAATAACAAGCCTGGTCAATCAAACCGCTCAATGCGTCTAACAGCTAATGGGATGG GGATACCATCTGCTTTCATATCGCACGAATTTGGTAAGGCCATGTCCCAATTAAATGGCAATGGTACAGGAAGTTTAGAG TTTGACAGTGTGGTCTCAAAAGCACCGAGTCAAAAAGGCAATGAAATGAATCATTTTTCAAATTGGGGCCTAACTTCTGA TGGCTATTTAAAACCTGACATTACTGCACCAGGTGGCGATATCTATTCTACCTATAACGATAACCACTATGGTAGCCAAA CAGGAACAAGTATGGCCTCTCCTCAGATTGCTGGCGCCAGCCTTTTGGTCAAACAATACCTAGAAAAGACTCAGCCAAAC TTGCCAAAAGAAAAAATTGCTGATATCGTTAAGAACCTATTGATGAGCAATGCTCAAATTCATGTTAATCCAGAGACAAA AACGACCACCTCACCGCGTCAGCAAGGGGCAGGATTACTTAATATTGACGGAGCTGTCACTAGCGGCCTTTATGTGACAG GAAAAGACAACTATGGCAGTATATCATTAGGCAACATCACAGATACGATGACGTTTGATGTGACTGTTCACAACCTAAGC AATAAAGACAAAACATTACGTTATGACACAGAATTGCTAACAGATCATGTAGACCCACAAAAGGGCCGCTTCACTTTGAC TTCTCACTCCTTAAAAACGTACCAAGGAGGAGAAGTTACAGTCCCAGCCAATGGAAAAGTGACTGTAAGGGTTACCATGG ATGTCTCACAGTTCACAAAAGAGCTAACAAAACAGATGCCAAATGGTTACTATCTAGAAGGTTTTGTCCGCTTTAGAGAT AGTCAAGATGACCAACTAAATAGAGTAAACATTCCTTTTGTTGGTTTTAAAGGGCAATTTGAAAACTTAGCAGTTGCAGA AGAGTCCATTTACAGATTAAAATCTCAAGGCAAAACTGGTTTTTACTTTGATGAATCAGGTCCAAAAGACGATATCTATG TCGGTAAACACTTTACAGGACTTGTCACTCTTGGTTCAGAGACCAATGTGTCAACCAAAACGATTTCTGACAATGGTCTA CACACACTTGGCACCTTTAAAAATGCAGATGGCAAATTTATCTTAGAAAAAAATGCCCAAGGAAACCCTGTCTTAGCCAT TTCTCCAAATGGTGACAACAACCAAGATTTTGCAGCCTTCAAAGGTGTTTTCTTGAGAAAATATCAAGGCTTAAAAGCAA GTGTCTACCATGCTAGTGACAAGGAACACAAAAATCCACTGTGGGTCAGCCCAGAAAGCTTTAAAGGAGATAAAAACTTT AATAGTGACATTAGATTTGCAAAATCAACGACCCTGTTAGGCACAGCATTTTCTGGAAAATCGTTAACAGGAGCTGAATT ACCAGATGGGCATTATCATTATGTGGTGTCTTATTACCCAGATGTGGTCGGTGCCAAACGTCAAGAAATGACATTTGACA TGATTTTAGACCGACAAAAACCGGTACTATCACAAGCAACATTTGATCCTGAAACAAACCGATTCAAACCAGAACCCCTA AAAGACCGTGGATTAGCTGGTGTTCGCAAAGACAGTGTCTTTTATCTAGAAAGAAAAGACAACAAGCCTTATACAGTTAC GATAAACGATAGCTACAAATATGTCTCAGTAGAAGACAATAAAACATTTGTGGAGCGACAAGCTGATGGCAGCTTTATCT TGCCGCTTGATAAAGCAAAATTAGGGGATTTCTATTACATGGTCGAGGATTTTGCAGGGAACGTGGCCATCGCTAAGTTA GGAGATCACTTACCACAAACATTAGGTAAAACACCAATTAAACTTAAGCTTACAGACGGTAATTATCAGACCAAAGAAAC GCTTAAAGATAATCTTGAAATGACACAGTCTGACACAGGTCTAGTCACAAATCAAGCCCAGCTAGCAGTGGTGCACCGCA ATCAGCCGCAAAGCCAGCTAACAAAGATGAATCAGGATTTCTTTATCTCACCAAACGAAGATGGGAATAAAGACTTTGTG GCCTTTAAAGGCTTGAAAAATAACGTGTATAATGACTTAACGGTTAACGTATACGCTAAAGATGACCACCAAAAACAAAC CCCTATCTGGTCTAGTCAAGCAGGCGCTAGTGTATCCGCTATTGAAAGTACAGCCTGGTATGGCATAACAGCCCGAGGAA GCAAGGTGATGCCAGGTGATTATCAGTATGTTGTGACCTATCGTGACGAACATGGTAAAGAACATCAAAAGCAGTACACC ATATCTGTGAATGACAAAAAACCAATGATCACTCAGGGACGTTTTGATACCATTAATGGCGTTGACCACTTTACTCCTGA CAAGACAAAAGCCCTTGACTCATCAGGCATTGTCCGCGAAGAAGTCTTTTACTTGGCCAAGAAAAATGGCCGTAAATTTG ATGTGACAGAAGGTAAAGATGGTATCACAGTTAGTGACAATAAGGTGTATATCCCTAAAAATCCAGATGGTTCTTACACC ATTTCAAAAAGAGATGGTGTCACACTGTCAGATTATTACTACCTTGTCGAAGATAGAGCTGGTAATGTGTCTTTTGCTAC CTTGCGTGACCTAAAAGCGGTCGGAAAAGACAAAGCAGTAGTCAATTTTGGATTAGACTTACCGGTCCCTGAAGACAAAC AAATAGTGAACTTTACCTACCTTGTGCGGGATGCAGATGGTAAACCGATTGAAAACCTAGAGTATTATAATAACTCAGGT AACAGTCTTATCTTGCCATACGGCAAATACACGGTCGAATTGTTGACCTATGACACCAATGCAGCCAAACTAGAGTCAGA TAAAATCGTTTCCTTTACCTTGTCAGCTGATAACAACTTCCAACAAGTTACCTTTAAGATAACGATGTTAGCAACTTCTC AAATAACTGCCCACTTTGATCATCTTTTGCCAGAAGGCAGTCGCGTTAGCCTTAAAACAGCTCAAGATCAGCTAATCCCG CTTGAACAGTCCTTGTATGTGCCTAAAGCTTATGGCAAAACCGTTCAAGAAGGCACTTACGAAGTTGTTGTCAGCCTGCC TAAAGGCTACCGTATCGAAGGCAACACAAAGGTGAATACCCTACCAAATGAAGTGCACGAACTATCATTACGCCTTGTCA AAGTAGGAGATGCCTCAGATTCAACTGGTGATCATAAGGTTATGTCAAAAAATAATTCACAGGCTTTGACAGCCTCTGCC ACACCAACCAAGTCAACGACCTCAGCAACAGCAAAAGCCCTACCATCAACGGGTGAAAAAATGGGTCTCAAGTTGCGCAT AGTAGGTCTTGTGTTACTCGGACTTACTTGCGTCTTTAGCCGAAAAAAATCAACCAAAGATTGA
Upstream 100 bases:
>100_bases CTCAGAAAAATGTGGTTAAATAATCAAATATTATTAACGAAAAATGAGTTAATGATTAACATTAAACTGGTTTTAGTTAA AACATTTAGGAGGGTATCAG
Downstream 100 bases:
>100_bases TAACAAAGCGCAAAGAGACAACAAATCATCCCTTTTAACAGTCTGACCTTTCTTTGAGATTGAGCTGGCAGATGATCATT TCTTAACAAAAGTTAAAGAG
Product: putative cell envelope proteinase
Products: NA
Alternate protein names: SCP [H]
Number of amino acids: Translated: 1647; Mature: 1647
Protein sequence:
>1647_residues MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPTITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNR EKEQSQDLVSEPTTTELADTDAASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKI YRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDI MGSAESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYG LVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFKDIKDSLGYDKSHQFAYVKESTDAGYNAQ DVKGKIALIERDPNKTYDEMIALAKKHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLE FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPN LPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLS NKDKTLRYDTELLTDHVDPQKGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKTISDNGL HTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNF NSDIRFAKSTTLLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPL KDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKL GDHLPQTLGKTPIKLKLTDGNYQTKETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFV AFKGLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYT ISVNDKKPMITQGRFDTINGVDHFTPDKTKALDSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYT ISKRDGVTLSDYYYLVEDRAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSG NSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQITAHFDHLLPEGSRVSLKTAQDQLIP LEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASA TPTKSTTSATAKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD
Sequences:
>Translated_1647_residues MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPTITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNR EKEQSQDLVSEPTTTELADTDAASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKI YRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDI MGSAESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYG LVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFKDIKDSLGYDKSHQFAYVKESTDAGYNAQ DVKGKIALIERDPNKTYDEMIALAKKHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLE FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPN LPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLS NKDKTLRYDTELLTDHVDPQKGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKTISDNGL HTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNF NSDIRFAKSTTLLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPL KDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKL GDHLPQTLGKTPIKLKLTDGNYQTKETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFV AFKGLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYT ISVNDKKPMITQGRFDTINGVDHFTPDKTKALDSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYT ISKRDGVTLSDYYYLVEDRAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSG NSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQITAHFDHLLPEGSRVSLKTAQDQLIP LEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASA TPTKSTTSATAKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD >Mature_1647_residues MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPTITNHAQQQAQHLTNTELSSAESKSQDTSQITLKTNR EKEQSQDLVSEPTTTELADTDAASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKI YRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDI MGSAESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYG LVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFKDIKDSLGYDKSHQFAYVKESTDAGYNAQ DVKGKIALIERDPNKTYDEMIALAKKHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLE FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPN LPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLS NKDKTLRYDTELLTDHVDPQKGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKTISDNGL HTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNF NSDIRFAKSTTLLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPETNRFKPEPL KDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKL GDHLPQTLGKTPIKLKLTDGNYQTKETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFV AFKGLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGDYQYVVTYRDEHGKEHQKQYT ISVNDKKPMITQGRFDTINGVDHFTPDKTKALDSSGIVREEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYT ISKRDGVTLSDYYYLVEDRAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSG NSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQITAHFDHLLPEGSRVSLKTAQDQLIP LEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASA TPTKSTTSATAKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD
Specific function: This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant [H]
COG id: COG1404
COG function: function code O; Subtilisin-like serine proteases
Gene ontology:
Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S8 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000209 - InterPro: IPR022398 - InterPro: IPR015500 - InterPro: IPR010435 - InterPro: IPR003137 - InterPro: IPR001899 [H]
Pfam domain/function: PF06280 DUF1034; PF02225 PA; PF00082 Peptidase_S8 [H]
EC number: =3.4.21.110 [H]
Molecular weight: Translated: 181290; Mature: 181290
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPTITNHAQQQAQHLTNTE CCCHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCH LSSAESKSQDTSQITLKTNREKEQSQDLVSEPTTTELADTDAASMANTGSDATQKSASLP HHCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCHHCCCCHHHHCCCCCCHHHCCCCCC PVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLAR CCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHCEEECCCCHHHHCCHHHHHHH QKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKI HHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCC YRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGER CCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCHHHCCCC FLGIAPEAQVMFMRVFANDIMGSAESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKP EEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCH LMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSK HHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHH WVIQRLMTVKELENRADLNHGKAIYSESVDFKDIKDSLGYDKSHQFAYVKESTDAGYNAQ HHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHH DVKGKIALIERDPNKTYDEMIALAKKHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFI CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHH SHEFGKAMSQLNGNGTGSLEFDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGD HHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCC IYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQI EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEE HVNPETKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLS EECCCCCCCCCHHHHCCCEEEECCCCCCCEEEEECCCCCCEEECCCCEEEEEEEEEECCC NKDKTLRYDTELLTDHVDPQKGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTK CCCCEEEECHHHHHCCCCCCCCEEEEEECCEEEECCCEEEECCCCEEEEEEEECHHHHHH ELTKQMPNGYYLEGFVRFRDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTG HHHHHCCCCEEEEEEEEECCCCCCCCCEECCCEEECCCCCCCEEHHHHHHHHHHHCCCCC FYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQ EEECCCCCCCCEEECCCEEEEEEECCCCCCEEEEECCCCCEEECCEECCCCCEEEECCCC GNPVLAISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNF CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCHHCCCCCCC NSDIRFAKSTTLLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQK CCCEEEEECEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCHHCCCHHHEEHHHHHCCCC PVLSQATFDPETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDN CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCC KTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDG CEEEEECCCCCEEEEECCCCCCCEEEEEEHHCCCEEEEHHHHHHHHHHCCCCEEEEECCC NYQTKETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFV CCCHHHHHHHCCCCCCCCCCEEECCEEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCEE AFKGLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGD EEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCC YQYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALDSSGIVRE EEEEEEEECCCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHCCCCCCHHH EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRA HHHHHHHCCCCEEEECCCCCCEEECCCEEEECCCCCCCEEEECCCCCEEEEEEEEEECCC GNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSG CCEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEECCCC NSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQITAHFD CEEEEECCCEEEEEEEECCCCCEECCCCEEEEEEECCCCEEEEEEEEEEEEECHHHHHHH HLLPEGSRVSLKTAQDQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEGNTKVNT HHCCCCCEEEEEECCCCCCCHHHHCCCCHHHCCHHHCCCEEEEEECCCCEEECCCCEECC LPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKSTTSATAKALPSTGEK CCHHHHEEEEEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCHH MGLKLRIVGLVLLGLTCVFSRKKSTKD HCEEEEHHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MEKKQRFSLRKYKSGTFSVLIGSVFLVMTTTVAADELSTMSEPTITNHAQQQAQHLTNTE CCCHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCH LSSAESKSQDTSQITLKTNREKEQSQDLVSEPTTTELADTDAASMANTGSDATQKSASLP HHCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCHHCCCCHHHHCCCCCCHHHCCCCCC PVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQSMRISDVSTAKVKSKEDMLAR CCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHCEEECCCCHHHHCCHHHHHHH QKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKI HHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCC YRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGER CCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCHHHCCCC FLGIAPEAQVMFMRVFANDIMGSAESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKP EEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCH LMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSK HHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHH WVIQRLMTVKELENRADLNHGKAIYSESVDFKDIKDSLGYDKSHQFAYVKESTDAGYNAQ HHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHH DVKGKIALIERDPNKTYDEMIALAKKHGALGVLIFNNKPGQSNRSMRLTANGMGIPSAFI CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHH SHEFGKAMSQLNGNGTGSLEFDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGD HHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCC IYSTYNDNHYGSQTGTSMASPQIAGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQI EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEE HVNPETKTTTSPRQQGAGLLNIDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLS EECCCCCCCCCHHHHCCCEEEECCCCCCCEEEEECCCCCCEEECCCCEEEEEEEEEECCC NKDKTLRYDTELLTDHVDPQKGRFTLTSHSLKTYQGGEVTVPANGKVTVRVTMDVSQFTK CCCCEEEECHHHHHCCCCCCCCEEEEEECCEEEECCCEEEECCCCEEEEEEEECHHHHHH ELTKQMPNGYYLEGFVRFRDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTG HHHHHCCCCEEEEEEEEECCCCCCCCCEECCCEEECCCCCCCEEHHHHHHHHHHHCCCCC FYFDESGPKDDIYVGKHFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQ EEECCCCCCCCEEECCCEEEEEEECCCCCCEEEEECCCCCEEECCEECCCCCEEEECCCC GNPVLAISPNGDNNQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNF CCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCHHCCCCCCC NSDIRFAKSTTLLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQK CCCEEEEECEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCHHCCCHHHEEHHHHHCCCC PVLSQATFDPETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDN CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCC KTFVERQADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDG CEEEEECCCCCEEEEECCCCCCCEEEEEEHHCCCEEEEHHHHHHHHHHCCCCEEEEECCC NYQTKETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFV CCCHHHHHHHCCCCCCCCCCEEECCEEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCEE AFKGLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASVSAIESTAWYGITARGSKVMPGD EEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCC YQYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALDSSGIVRE EEEEEEEECCCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHHCCCCCCHHH EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRA HHHHHHHCCCCEEEECCCCCCEEECCCEEEECCCCCCCEEEECCCCCEEEEEEEEEECCC GNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNNSG CCEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEECCCC NSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKITMLATSQITAHFD CEEEEECCCEEEEEEEECCCCCEECCCCEEEEEEECCCCEEEEEEEEEEEEECHHHHHHH HLLPEGSRVSLKTAQDQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEGNTKVNT HHCCCCCEEEEEECCCCCCCHHHHCCCCHHHCCHHHCCCEEEEEECCCCEEECCCCEECC LPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKSTTSATAKALPSTGEK CCHHHHEEEEEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCHH MGLKLRIVGLVLLGLTCVFSRKKSTKD HCEEEEHHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA