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The map label for this gene is engA [H]

Identifier: 15674498

GI number: 15674498

Start: 296863

End: 298173

Strand: Direct

Name: engA [H]

Synonym: SPy_0341

Alternate gene names: 15674498

Gene position: 296863-298173 (Clockwise)

Preceding gene: 15674497

Following gene: 15674499

Centisome position: 16.03

GC content: 42.79

Gene sequence:

>1311_bases
ATGGTTTTACCTACCGTTGCCATTGTGGGCCGTCCAAATGTGGGCAAGTCCACCTTATTTAATCGAATCGCAGGAGAGCG
CATTTCAATTGTAGAAGACGTTGAAGGGGTTACTCGTGACCGTATTTATGCTACTGGGGAGTGGCTTAACCGCCAATTCT
CATTGATTGATACAGGTGGTATTGATGACGTTGATGCCCCGTTTATGGAGCAAATCAAGCACCAGGCTCAAATTGCCATG
GAAGAAGCTGATGTTATCGTTTTTGTTGTTTCTGGTAAAGAAGGGGTGACCGACGCTGACGAATATGTGTCTAAAATTCT
GTATCGAACCAATACCCCAGTCATTTTAGCTGTTAATAAGGTTGATAATCCTGAAATGCGTAATGACATTTATGATTTTT
ATTCACTTGGTTTGGGTGATCCTTATCCAGTTTCTTCTGTTCATGGTATCGGAACAGGGGATGTCTTAGATGCGATCGTT
GAAAACTTGCCAGTAGAAGAGGCTGAAGAAAATGATGATATTATTCGCTTCAGTTTAATCGGTCGTCCTAATGTTGGGAA
ATCTAGCTTGATTAACGCTATTTTAGGTGAGGACCGTGTTATCGCTAGCCCTGTCGCAGGGACAACACGTGATGCCATTG
ACACGCATTTTACGGATGCTGACGGTCAAGAATTTACCATGATTGACACGGCTGGAATGCGCAAATCTGGCAAGATTTAC
GAAAATACAGAGAAATATTCTGTCATGCGTGCCATGCGTGCCATTGACCGCTCCGATGTGGTCTTGATGGTTATCAATGC
TGAAGAAGGTATCCGTGAATACGACAAGCGTATCGCTGGCTTTGCACACGAAGCTGGTAAAGGAATGATTATCGTGGTTA
ACAAATGGGATACCATTGACAAGGATAATCATACCGTTGCTAAGTGGGAAGCCGATATTCGTGACCAATTCCAATTTTTG
ACATACGCTCCGATTATTTTTGTGTCAGCTTTGACGAAGCAGCGCCTCAACAAATTGCCTGACTTGATTAAACGTATCAG
TGAGAGTCAGAATAAACGTATCCCATCTGCTGTCCTCAATGATGTTATCATGGATGCTATTGCCATTAATCCAACGCCAA
CGGATAAGGGTAAACGTTTGAAAATTTTCTATGCCACTCAAGTGTCAGTAAAGCCACCAACATTTGTCGTCTTTGTTAAC
GAGGAAGAATTGATGCACTTCTCTTATCTACGCTTCTTGGAAAACCAGATTCGCGCAGCCTTTACCTTTGAAGGGACACC
GATTCATCTAATTGCTCGCAAACGAAAATAA

Upstream 100 bases:

>100_bases
CTAGAGAGTTTCATTTAGAAGGGGCTAACCGCCGTTAAGTTTGAGATAGCAATCAAGAAGAATAGCTACACGTATGAGTG
AGTGAAAGAAAAGGAGAATC

Downstream 100 bases:

>100_bases
GAAATGAACATCAACTAAAATGCTGACCTAAGAAATAATCTCATCATTGATAAGGACTGTGTTGTGTATGTTACAGGAGA
CAGTCCTTTTTATAATACCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAM
EEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFL
TYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK

Sequences:

>Translated_436_residues
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAM
EEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFL
TYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
>Mature_436_residues
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAM
EEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFL
TYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVN
EEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=458, Percent_Identity=37.5545851528384, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1788919, Length=165, Percent_Identity=32.7272727272727, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=208, Percent_Identity=30.2884615384615, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48802; Mature: 48802

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHEEEEHHHHCCEEEEEECCC
IDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNK
CCCCCCHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIVENLPVEEAEENDDIIRFSLI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTID
CCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
KDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLN
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVNEEELMHFSYLRFLENQIRAA
HHHHHHEECCCCCCCCCCEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCEE
FTFEGTPIHLIARKRK
EEECCCCEEEEEECCC
>Mature Secondary Structure
MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCHHHHEEEEHHHHCCEEEEEECCC
IDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNK
CCCCCCHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIVENLPVEEAEENDDIIRFSLI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTID
CCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
KDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLN
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVNEEELMHFSYLRFLENQIRAA
HHHHHHEECCCCCCCCCCEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCEE
FTFEGTPIHLIARKRK
EEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA