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The map label for this gene is nrdR [H]

Identifier: 15674495

GI number: 15674495

Start: 294244

End: 294738

Strand: Direct

Name: nrdR [H]

Synonym: SPy_0338

Alternate gene names: 15674495

Gene position: 294244-294738 (Clockwise)

Preceding gene: 15674494

Following gene: 15674496

Centisome position: 15.88

GC content: 38.59

Gene sequence:

>495_bases
GTGCGTTGTCCAAAATGTAATTACCATAAATCGAGTGTTGTTGACAGTAGACAAGCTGAAGACGGCAACACCATTCGTCG
TCGAAGAGAATGTGAACAGTGTCATACTCGCTTTACTACCTTTGAGCGTGTTGAAGAACTCCCTTTATTAGTCATCAAAA
AAGATGGCACACGAGAGCAATTTTCTAGAGATAAAATATTAAATGGGGTTGTTCAAAGTGCGCAAAAACGACCTGTCTCG
AGCACAGATATTGAAAATGTCATTTCTCGTATTGAACAAGAAGTTCGAACAACCTACGAAAATGAAGTGTCAAGTACTGC
TATTGGTAATTTAGTGATGGATGAGTTGGCCGAACTCGATGAAATCACATATGTACGCTTTGCTAGTGTCTACAAGAGTT
TCAAGGACGTTGATGAAATCGAAGAACTTTTGCAACAAATTACGAATCGCGTACGCGGAAAGAAAAAACGTTTAAATAAT
GATGAAACCAATTGA

Upstream 100 bases:

>100_bases
TGACATGAAAGAAATACTGTCAATCGCGATGTCTTTTGTTATCCTTGAGAATATGGTAAAATAGTATATTAGATTAATTT
GATAGAATTGGGGTGTTTGC

Downstream 100 bases:

>100_bases
TACTTTTACATATCTAAAACGCAACAAAGTAACTCTTGATTCGGTGACTTTAATACAGTTGTACTTTCCAATTATTGGAA
GTGACGCGGTCTCTATCTAC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVS
STDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
DETN

Sequences:

>Translated_164_residues
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVS
STDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
DETN
>Mature_164_residues
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVS
STDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
DETN

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.8979591836735, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 19132; Mature: 19132

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQ
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
FSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELD
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNNDETN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQ
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
FSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELD
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNNDETN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA