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The map label for this gene is nadD

Identifier: 15674475

GI number: 15674475

Start: 274191

End: 274823

Strand: Direct

Name: nadD

Synonym: SPy_0308

Alternate gene names: 15674475

Gene position: 274191-274823 (Clockwise)

Preceding gene: 15674474

Following gene: 15674476

Centisome position: 14.8

GC content: 39.18

Gene sequence:

>633_bases
ATGGCATTAGAATTGTTGACGCCTTTTACGAAGGTGGAATTAGAGGAAGAAAAAAAAGAAAGCAACCGCAAACAGATTGG
GATTTTAGGAGGGAATTTTAATCCTATTCACAATGCACACCTTGTGGTTGCAGATCAAGTTCGCCAGCAATTAGGATTAG
ATCAGGTGCTATTGATGCCTGAATGTAAACCACCGCATGTGGATGCCAAAGAGACTATTGATGAGAAGCATCGTCTTCGC
ATGTTGGAATTGGCTATTGAAGATGTTGAAGGGCTAGCTATTGAAACCTGTGAACTTGAACGTCAGGGAATCAGCTATAC
CTATGATACGATGCTTTATTTGACTGAGCAGCATCCTGATGTTGATTTTTATTTTATCATCGGAGCTGATATGGTTGATT
ATTTGCCAAAGTGGCACCGTATTGATGAACTGGTCAAACTCGTTCAATTTGTTGGAGTTCAACGTCCAAAATATAAAGCT
GGAACCTCTTACCCGGTCATTTGGGTAGATCTTCCTTTGATAGATATTTCTTCTAGTATGATTAGGGATTTTATTAAAAA
AGGTCGTCAGCCCAATTATCTCTTACCTAAGCGGGTTTTAGACTACATTACTCAAGAAGGTTTGTATCAATGA

Upstream 100 bases:

>100_bases
GCAAGTTGTCCCCTAAAGTTAAAGCAATCTAGTCCTTTTATTTGTATAGGGACTGGTTTTATGAGACGAGGACTATTGTC
GCGAGAATTTTGGAGAAAGT

Downstream 100 bases:

>100_bases
CATATGAAGATTATCTTCCTTATAGCAGGACCGAACTGTTAGCAAAAATTGCAGAGCAGATGAGCCCTAAACGGTTTAAA
CATGTACTTGGCGTGGAAAA

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLR
MLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
GTSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ

Sequences:

>Translated_210_residues
MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLR
MLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
GTSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ
>Mature_209_residues
ALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRM
LELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKAG
TSYPVIWVDLPLIDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=209, Percent_Identity=30.1435406698565, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_STRP1 (Q9A1F2)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268649.1
- RefSeq:   YP_281627.1
- ProteinModelPortal:   Q9A1F2
- SMR:   Q9A1F2
- EnsemblBacteria:   EBSTRT00000000127
- EnsemblBacteria:   EBSTRT00000029001
- GeneID:   3572631
- GeneID:   900597
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0308
- KEGG:   spz:M5005_Spy_0263
- GeneTree:   EBGT00050000028322
- HOGENOM:   HBG739448
- OMA:   HLLMANE
- ProtClustDB:   PRK00071
- BioCyc:   SPYO160490:SPY0308-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0263-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 24370; Mature: 24238

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMP
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHCCCEEEECC
ECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCEEEHEEEEEECCCCC
VDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKAGTSYPVIWVDLPLIDISSSM
CEEEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHCCHHH
IRDFIKKGRQPNYLLPKRVLDYITQEGLYQ
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMP
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHCCCEEEECC
ECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCEEEHEEEEEECCCCC
VDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKAGTSYPVIWVDLPLIDISSSM
CEEEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHCCHHH
IRDFIKKGRQPNYLLPKRVLDYITQEGLYQ
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296