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The map label for this gene is sufB [H]

Identifier: 15674464

GI number: 15674464

Start: 252424

End: 253842

Strand: Direct

Name: sufB [H]

Synonym: SPy_0290

Alternate gene names: 15674464

Gene position: 252424-253842 (Clockwise)

Preceding gene: 15674463

Following gene: 15674466

Centisome position: 13.63

GC content: 40.31

Gene sequence:

>1419_bases
ATGTCTGATATAAATGAGAAAGTAGAGCCAAAGCCAATTGACTTAGGGGACTACCAATTTGGATTTCACGATGATGTAGA
GCCCATTTATTCTACAGGAAAAGGATTGAGTGAGGCAGTGGTTCGCGAACTATCAGCTGCCAAAAATGAACCTGAGTGGA
TGTTGGAGTTTCGTTTAAAATCCTTGGAAACCTTTAATAAAATGCCGATGCAAACCTGGGGAGCAGACTTATCAGATATT
AACTTTGATGATATCATTTACTATCAAAAAGCATCTGATAAGCCAGCTCGTTCTTGGGATGATGTTCCAGAAAAAATAAA
AGAAACCTTTGATCGTATTGGAATTCCAGAAGCAGAACGTGCTTATCTTGCTGGGGCATCAGCTCAGTATGAGTCAGAAG
TGGTTTACCATAACATGAAGGGTGAATTTGAAAAGCTAGGGATTATCTTTACAGATACCGATTCCGCCCTCAAAGAATAT
CCTGATTTGTTCAAACAATACTTTGCCAAACTGGTTCCGCCAACAGACAACAAATTAGCAGCCCTTAATTCAGCAGCTTG
GTCTGGTGGTACCTTTATTTATGTTCCTAAAGGGGTCAAGGTAGATATCCCTTTGCAAACTTATTTCCGCATTAACAATG
AAAATACTGGTCAATTTGAGCGGACATTGATTATTGTTGATGAAGGAGCAAGTGTTCATTATGTTGAAGGATGTACAGCT
CCCACTTATTCAAGTAACAGCTTACATGCTGCTATCGTTGAAATCTTTGCGCTTGATGGTGCATACATGCGTTATACCAC
CATTCAAAACTGGTCAGACAATGTGTATAATCTAGTAACAAAACGTGCACGCGCCCTTACGGATGCAACAGTGGAATGGA
TTGATGGCAATCTAGGAGCTAAAACCACCATGAAGTACCCTTCTGTTTATCTTGATGGGCCAGGTGCGCGTGGCACCATG
CTGTCTATTGCCTTTGCTAATGCAGGTCAACACCAAGATACAGGGGCTAAAATGATTCACAATGCTCCACATACATCATC
ATCAATTGTGTCAAAATCAATTGCCAAGTCTGGTGGTAAAGTAGATTATCGTGGCCAAGTGACCTTTAACAAGCAATCTA
AAAAATCCGTTTCCCATATTGAATGTGATACTATTTTGATGGACGATATTTCTAAATCAGATACAATCCCATTTAACGAA
ATTCATAATTCACAGGTGGCGTTAGAACATGAAGCCAAAGTGTCTAAGATTTCTGAAGAACAACTCTACTATCTCATGAG
CCGTGGCTTATCAGAAAGCGAAGCCACAGAGATGATTGTCATGGGATTTGTGGAGCCTTTTACCAAAGAATTGCCAATGG
AATACGCGGTCGAACTCAATCGATTGATTTCCTATGAGATGGAAGGTTCTGTCGGTTAA

Upstream 100 bases:

>100_bases
ATCAAATGCTCTACCCTAGCTTGGAATGCTCTCAAGGAAGCCATTAAACGAAGTGCCAATGCTCAGCACCTCACGGACCA
AAATGTAAAGGAAGGGAAAA

Downstream 100 bases:

>100_bases
TTGCATTTTCTCTTATCCATCTGAAAGATCTTTGAGATAGGATTTTATGAGTTGTAGTACTAACCCCAAGTGGTTAGTTT
TTAGTTGCCTTGAACACGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVRELSAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDI
NFDDIIYYQKASDKPARSWDDVPEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
PDLFKQYFAKLVPPTDNKLAALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTA
PTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTM
LSIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISKSDTIPFNE
IHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG

Sequences:

>Translated_472_residues
MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVRELSAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDI
NFDDIIYYQKASDKPARSWDDVPEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
PDLFKQYFAKLVPPTDNKLAALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTA
PTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTM
LSIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISKSDTIPFNE
IHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG
>Mature_471_residues
SDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVRELSAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDIN
FDDIIYYQKASDKPARSWDDVPEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEYP
DLFKQYFAKLVPPTDNKLAALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTAP
TYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTML
SIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISKSDTIPFNEI
HNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=464, Percent_Identity=39.2241379310345, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1787971, Length=154, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 52783; Mature: 52652

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVRELSAAKNEPEWMLEFRLK
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
SLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDVPEKIKETFDRIGIPEAER
HHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEYPDLFKQYFAKLVPPTDNKLA
HHHCCCCCCCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEE
ALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTA
EECCCCCCCCEEEEECCCCEEEECCEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCC
PTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRARALTDATVEWIDGNLGA
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
KTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKSGGK
CEEEECCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCC
VDYRGQVTFNKQSKKSVSHIECDTILMDDISKSDTIPFNEIHNSQVALEHEAKVSKISEE
EEEEEEEEECCCCCCCCCCEEECEEEECCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHH
QLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
SDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVRELSAAKNEPEWMLEFRLK
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
SLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDVPEKIKETFDRIGIPEAER
HHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEYPDLFKQYFAKLVPPTDNKLA
HHHCCCCCCCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEE
ALNSAAWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTA
EECCCCCCCCEEEEECCCCEEEECCEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCC
PTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRARALTDATVEWIDGNLGA
CCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
KTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKSGGK
CEEEECCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCC
VDYRGQVTFNKQSKKSVSHIECDTILMDDISKSDTIPFNEIHNSQVALEHEAKVSKISEE
EEEEEEEEECCCCCCCCCCEEECEEEECCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHH
QLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]