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The map label for this gene is purR [H]

Identifier: 15674448

GI number: 15674448

Start: 232224

End: 233063

Strand: Direct

Name: purR [H]

Synonym: SPy_0268

Alternate gene names: 15674448

Gene position: 232224-233063 (Clockwise)

Preceding gene: 15674447

Following gene: 15674449

Centisome position: 12.54

GC content: 37.14

Gene sequence:

>840_bases
ATGAAATTAAGACGAAGTGAACGTATGGTTGTCATTTCAAATTATTTGATTAACAATCCGTATAAATTAACTAGTTTAAA
CACCTTTGCAACTAAATATGAGGCCGCAAAATCTTCTATCTCAGAAGATATCGCTATTATCAAGAAAGCTTTTGAAGAAG
CTAACATTGGTGATATCGATACACTTACAGGAGCAAGTGGAGGCGTAATTTTTACCCCCAGTATTTCAGAAACAGAAGCG
CGTACCATTGTTGAAGACCTGTGTCAAAGGTTATCAGAGAGTGATCGCATCTTACCTGGAGGCTATATCTATTTGTCAGA
CTTGCTGAGTACACCTAAAATTTTACAAAATATTGGTCGTATTATTGCCAATGCCTTTAAAGGAGAAAAGATTGACGCTG
TGATGACAGTTGCAACCAAAGGAGTTCCTTTAGCAAATGCAGTGGCTAATATTTTAAGTGTTCCTTTTGTCATTGTTAGA
CGTGATTTAAAAATAACAGAAGGATCGACAGTGTCTGTCAATTATGCGAGTGCTTCTAGTGATCGTATTGAAAAGATGTT
TCTGTCAAAGCGTAGTTTGAAACCCAATAGTCGTGTATTGATTGTAGATGATTTCTTGAAGGGCGGGGGGACGATTACAG
GAATGATCAGTCTCTTGACAGAATTTGACAGCACTTTAGTTGGTGTTGCTGTGTTTGCAGAAAACGCTCAATCAGAGCGT
GAGCAAATGACCTTCAAATCATTGCTGAAAGTTTCAGAGATTGATGTCAAAAACAACAATGTTGTTGTAGAAGTTGGTAA
TATTTTCGATAAATGGAAAAAGGAGAGAGAATGGACTTAG

Upstream 100 bases:

>100_bases
TATTAATAAGAACAAAAAAACCAATATTTTCCTAATCGAATGTTCGTTTTTTATTAACTTTATGGTATAATAGCAAAAAG
TACATAAAAATGGGGAAACT

Downstream 100 bases:

>100_bases
AACAAACGAAGCCAAACCAAGTTAAGCAGAAAATTGCTTTAACCTCAACAATTGCTTTATTGAGTGCCAGTGTAGGCGTA
TCTCACCAAGTCAAAGCAGA

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEA
RTIVEDLCQRLSESDRILPGGYIYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSER
EQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKEREWT

Sequences:

>Translated_279_residues
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEA
RTIVEDLCQRLSESDRILPGGYIYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSER
EQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKEREWT
>Mature_279_residues
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEA
RTIVEDLCQRLSESDRILPGGYIYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSER
EQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKEREWT

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- ProDom:   PD029816 [H]

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N [H]

EC number: NA

Molecular weight: Translated: 30726; Mature: 30726

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFEEANIGDID
CCCCCCCCEEEEEHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGYIYLSDLLSTPKILQNIGR
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHH
IIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVRRDLKITEGSTVSVNYASASS
HHHHHHCCCCHHHEEEEHHCCCCHHHHHHHHHHCCHHEEECCCEECCCCEEEEEECCCCH
DRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSER
HHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKEREWT
HHHHHHHHHHHHHEEECCCCEEEEECHHHHHHHHHCCCC
>Mature Secondary Structure
MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDIAIIKKAFEEANIGDID
CCCCCCCCEEEEEHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGYIYLSDLLSTPKILQNIGR
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHH
IIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVRRDLKITEGSTVSVNYASASS
HHHHHHCCCCHHHEEEEHHCCCCHHHHHHHHHHCCHHEEECCCEECCCCEEEEEECCCCH
DRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISLLTEFDSTLVGVAVFAENAQSER
HHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKEREWT
HHHHHHHHHHHHHEEECCCCEEEEECHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]