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The map label for this gene is rsgA

Identifier: 15674443

GI number: 15674443

Start: 227587

End: 228459

Strand: Direct

Name: rsgA

Synonym: SPy_0263

Alternate gene names: 15674443

Gene position: 227587-228459 (Clockwise)

Preceding gene: 15674442

Following gene: 15674444

Centisome position: 12.29

GC content: 43.18

Gene sequence:

>873_bases
TTGCAAGGTAAAATCATTAAATCTCTGGCTGGTTTTTATTACGTGGAGTCAGAAGGACAGGTATATCAGACGCGAGCGCG
TGGTAATTTTAGGAAGCGCGGTGAGACACCTTATGTTGGAGATATCGTGGATTTCTCAGCAGAGGACAACTCTGAAGGTT
ATATTTTAGCGATTCATCCTCGTAAAAACAGTTTGGTAAGACCTCCTATCGTCAATATTGATCAAGCAGTGGTTATTATG
TCTGCTAAAGAACCAGAATTTAACAGCAATCTTCTAGACCGCTTTCTCATCTTGCTTGAACACAAAGCCATTCATCCAGT
GGTTTATATCTCTAAGATGGACTTATTAGATAGTCCCGAGGAGATTAAGGCTATTGGTCGACAGTATCAGGCAATCGGTT
ACGATTTTGTGACCAGTCTTGAGGAATTGCTGCCTTTGCTAGCTGATAAAATTACCGTCTTTATGGGACAAACAGGTGTT
GGGAAATCAACCCTTCTCAACCGAATCGCCCCCGAATTGGCTCTTGAAATAGGAGAAATCTCAGATAGTCTAGGGCGTGG
TCGTCACACCACCCGAGCTGTGAGTTTTTACAATACCCATGGCGGAAAAATCGCGGATACGCCAGGTTTTTCATCATTAG
ACTATGATATTGCTAATGCTGAAGATTTGAACGAGGCTTTTCCAGAGCTGCGCCGGCTGAGCCATGAGTGTAAGTTTAGA
TCCTGTACCCATACCCACGAACCCAAGTGTGCTGTCAAGGCAGCGCTTGAAACGGGAGAGTTGTGGCCAGTTCGTTATGA
GCATTACCTGCAATTTCTCAGTGAAATTGAAAACCGTCGTGAAACATATAAAAAAGTTATCAAAAGAAAGTAG

Upstream 100 bases:

>100_bases
CTTGACAGTTTTTAAAGCGAGTGAAACTTAGACTCAAATGCTGATTTGGGAGCGGTTTTCTGATATAATAGAGTTATTAT
AGTAGGGCAAAGGAGCACAG

Downstream 100 bases:

>100_bases
GTCTACTCCATGTCAACTCTAAAAATTGCCCCATCTATTCTAGCAGCTGATTATGCTAATTTTGCTTCTGAGCTAGCTCG
TATTGAAGAAACAGATGCCG

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIM
SAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
GKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFR
SCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK

Sequences:

>Translated_290_residues
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIM
SAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
GKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFR
SCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
>Mature_290_residues
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIM
SAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
GKSTLLNRIAPELALEIGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFR
SCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=310, Percent_Identity=34.5161290322581, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_STRP1 (Q9A1H9)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268617.1
- RefSeq:   YP_281587.1
- ProteinModelPortal:   Q9A1H9
- SMR:   Q9A1H9
- EnsemblBacteria:   EBSTRT00000000237
- EnsemblBacteria:   EBSTRT00000027606
- GeneID:   3572690
- GeneID:   900563
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0263
- KEGG:   spz:M5005_Spy_0223
- GeneTree:   EBGT00050000027431
- HOGENOM:   HBG652450
- OMA:   FRDCKHL
- ProtClustDB:   PRK00098
- BioCyc:   SPYO160490:SPY0263-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0223-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 32865; Mature: 32865

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIHP
CCCHHHHHHHCEEEECCCCCEEEEHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEEEEC
RKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPE
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCHH
EIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGVGKSTLLNRIAPELALEIGEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
SDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFR
HHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
SCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVDFSAEDNSEGYILAIHP
CCCHHHHHHHCEEEECCCCCEEEEHHCCCHHHCCCCCCCCCEEECCCCCCCCCEEEEEEC
RKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHKAIHPVVYISKMDLLDSPE
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCHH
EIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGVGKSTLLNRIAPELALEIGEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
SDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIANAEDLNEAFPELRRLSHECKFR
HHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
SCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEIENRRETYKKVIKRK
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296