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The map label for this gene is gpsA [H]

Identifier: 15674414

GI number: 15674414

Start: 198595

End: 199611

Strand: Reverse

Name: gpsA [H]

Synonym: SPy_0226

Alternate gene names: 15674414

Gene position: 199611-198595 (Counterclockwise)

Preceding gene: 15674439

Following gene: 15674413

Centisome position: 10.78

GC content: 42.77

Gene sequence:

>1017_bases
ATGACAAAACAAAAAGTAGCTATTTTAGGACCTGGTTCTTGGGGAACTGCCCTTTCTCAGGTTCTTAATGACAATGGCCA
TGACGTCCGTTTATGGGGAAATATTCCTGATCAAATTGAAGAGATAAATACCAAGCATACCAATAGACACTACTTCAAAG
ACATTGTGTTAGACAAAAACATTACGGCAACTCTTGATTTAGGTCAAGCCCTATCAGATGTTGATGCGGTGCTTTTTGTT
GTGCCAACTAAAGTAACACGATTAGTTGCTAGACAAGTTGCCGCCATTTTAGATCATAAAGTAGTGGTCATGCATGCCTC
AAAAGGTCTAGAACCAGAGACCCACGAACGTTTATCAACTATCCTAGAAGAAGAAATTCCAGCTCATTTTCGTAGTGAAG
TGGTCGTTGTATCAGGTCCTAGTCATGCTGAAGAAACTATCGTTCGCGATATTACTCTCATCACGGCAGCCTCAAAAGAT
ATTGAAGCTGCAAAGTATGTTCAGTCCCTCTTTAGTAACCACTACTTCCGACTTTATACCAATACCGACGTCATCGGAGT
TGAAACAGCTGGTGCCCTCAAAAACATTATTGCTGTTGGAGCAGGAGCTCTCCATGGACTTGGGTATGGAGATAATGCCA
AAGCAGCGGTAATTACTCGTGGGTTAGCTGAAATCACCCGTCTAGGCGTCAAGCTTGGTGCTGACCCGTTAACCTACAGT
GGGTTATCTGGTGTTGGTGATCTAATTGTAACAGGTACTTCTGTCCATTCACGTAACTGGCGGGCTGGAGCTGCCCTTGG
ACGTGGTGAAAAATTAGAAGATATTGAACGCAACATGGGTATGGTTATCGAAGGTATCGCAACAACTAAGGTAGCCTATG
AAATTGCCCAAGACCTCGGAGTTTACATGCCAATTACAACAGCTATTTATAAGTCCATCTACGAGGGCGCTGATATCAAA
GAAAGCATCCTCGGCATGATGTCAAATGAATTTCGTTCTGAAAATGAATGGCATTAA

Upstream 100 bases:

>100_bases
TGGGAACGCCTTATTAGCCAAGACCATATACCTTTTCTAATAGAGCTAATCAAGGTGTTATGTTATAATAGAGTGACTAG
CTCTTGAAGGAGAATTTAGA

Downstream 100 bases:

>100_bases
GCCATGCGTCACTAAAATAAGAGGAGGTGCTGATGACCAAAGTCAGAAAAGCTATTATTCCCGCAGCAGGTTTAGGCACA
CGTTTTTTACCTGCAACCAA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFV
VPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
GLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIK
ESILGMMSNEFRSENEWH

Sequences:

>Translated_338_residues
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFV
VPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
GLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIK
ESILGMMSNEFRSENEWH
>Mature_337_residues
TKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVV
PTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDI
EAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSG
LSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKE
SILGMMSNEFRSENEWH

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=347, Percent_Identity=31.4121037463977, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI24307999, Length=346, Percent_Identity=30.3468208092486, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1790037, Length=338, Percent_Identity=39.0532544378698, Blast_Score=238, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI32564399, Length=334, Percent_Identity=29.0419161676647, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193210136, Length=342, Percent_Identity=28.6549707602339, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=342, Percent_Identity=28.6549707602339, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17507425, Length=334, Percent_Identity=26.6467065868263, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193210134, Length=333, Percent_Identity=26.4264264264264, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=349, Percent_Identity=28.6532951289398, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324513, Length=350, Percent_Identity=27.1428571428571, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136204, Length=332, Percent_Identity=29.5180722891566, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136200, Length=332, Percent_Identity=29.5180722891566, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136202, Length=332, Percent_Identity=29.5180722891566, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI22026922, Length=333, Percent_Identity=23.1231231231231, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362270, Length=294, Percent_Identity=26.1904761904762, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45551945, Length=294, Percent_Identity=26.1904761904762, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648969, Length=282, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36681; Mature: 36550

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHCCCC
ITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLST
CEEEEHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
ILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYT
HHHHHCCHHHHCCEEEEECCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHCC
VYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKN
CCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHCCCC
ITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLST
CEEEEHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
ILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYT
HHHHHCCHHHHCCEEEEECCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHCC
VYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA