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The map label for this gene is ulaA [H]

Identifier: 15674379

GI number: 15674379

Start: 159941

End: 161368

Strand: Direct

Name: ulaA [H]

Synonym: SPy_0174

Alternate gene names: 15674379

Gene position: 159941-161368 (Clockwise)

Preceding gene: 15674378

Following gene: 15674380

Centisome position: 8.63

GC content: 42.58

Gene sequence:

>1428_bases
ATGCTCCTAGCTCCCCTAAACTGGTTCTCGCAAAATATTTTGCAAAACCCAGCGTTCTTTGTAGGTCTTTTGGTTTTAAT
CGGGTATTTACTCCTTAAAAAACCCATTTATGAGGTCTTTGCTGGTTTTGTAAAGGCTACCGTTGGTTACTTGATTTTGA
ACGTTGGAGCAGGCGGTCTTGTAACGACTTTTCGTCCGATCTTGGTTGCTCTTGCCAAGAAATTTGAATTGAAAGCCGCC
GTTATTGATCCTTATTTTGGTTTGGCTGCTGCTAATACTAAGTTAGAAGAGATGGGCTTCATCAGTGTTGCTACGACAGC
TCTCTTGATTGGATTTGGGGTCAACATTCTTTTGGTTGCACTTCGCAAGGTCACTAAAGTTCGTACCCTTTTCATCACAG
GTCACATCATGGTCCAACAGGCAGCGACGATTTCGGTCTTTGTCCTTCTTTTAATCCCTCAATTCCAAAATGCTTTTGGG
GCATGGGCAGTCGGTATCATCTGTGGGCTTTACTGGGCTATCAGCTCAAACATGACCGTTGAAGCAACTCAACGCCTTAC
AGGTGGCGGTGGGTTTGCGATTGGTCACCAACAACAATTTGCGATTTGGTTTGTGGATAAGGTTGCACCGTTCTTTGGTA
AAAAAGAAGAAAACCTTGATAACCTAAAATTACCGACCTTCTTAAACATTTTCCATGATACTGTTGTTGCGTCAGCAACT
TTGATGTTGGTCTTTTTCGGAGCTATCTTGGCTGTCCTTGGTCCAGACATTATGTCTGATGTGGACTTAATCGGACCTGG
AGCATTCAACCCAGCTAAGCAAGCTTTCTTCATGTATATTTTGCAAACCTCTCTCACCTTCTCAGTTTATCTCTTTATCT
TGATGCAGGGTGTTCGCATGTTTGTTTCTGAATTGACCAATGCTTTTCAAGGGATCTCAAGCAAATTGCTTCCAGGGTCA
TTCCCAGCGGTTGACGTTGCAGCTTCCTATGGCTTTGGTTCTTCAAATGCGGTGCTTTCAGGATTTGCCTTTGGTTTGAT
TGGTCAATTAATCACCATTGCTCTTCTTGTTATCTTTAAAAATCCAATCTTAATTATCACAGGATTCGTTCCCGTATTCT
TTGATAATGCGGCAATTGCGGTTTATGCAGATAAACGTGGTGGCTGGAAAGCAGCGGTAGCTCTATCATTTATCTCAGGT
ATTTTGCAAGTTGCACTTGGTGCTGTTGCTGTAGGTCTTTTAGGACTTACAGGTGGTTATCACGGTAATATCGACTTGGT
TCTTCCATGGTTACCATTTGGGTACCTCTTCAAATTCCTTGGTATTGCAGGGTATGTGCTTGTTTGCATCTTCTTACTTG
CCATTCCACAATTGCAATTCGCAAAAGCTAAGGACAAAGAAGCTTACTACCGTGGGGAAGCTCAATAA

Upstream 100 bases:

>100_bases
TGTGTGATAGTTGGTCTTTTTTAAAACGCTTTCATTACCTATAATGAACATATAAACACTTTATCTTTATTAACTTTGAA
AAGAGGTAGTTCTTATGGAA

Downstream 100 bases:

>100_bases
CACTGCATCTTAAGAAATAGCTCTGCTATTTTAACAAAACAATAATAAAACATTTTCGGAGGAAAAAACAATGGTTAAAG
TCTTAACAGCATGTGGCAAT

Product: PTS system ascorbate-specific transporter subunit IIC

Products: protein histidine; sugar phosphate

Alternate protein names: Ascorbate-specific PTS system EIIC component [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAGFVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAA
VIDPYFGLAAANTKLEEMGFISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNAFG
AWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKEENLDNLKLPTFLNIFHDTVVASAT
LMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQAFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGS
FPAVDVAASYGFGSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWKAAVALSFISG
ILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLVCIFLLAIPQLQFAKAKDKEAYYRGEAQ

Sequences:

>Translated_475_residues
MLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAGFVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAA
VIDPYFGLAAANTKLEEMGFISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNAFG
AWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKEENLDNLKLPTFLNIFHDTVVASAT
LMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQAFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGS
FPAVDVAASYGFGSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWKAAVALSFISG
ILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLVCIFLLAIPQLQFAKAKDKEAYYRGEAQ
>Mature_475_residues
MLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAGFVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAA
VIDPYFGLAAANTKLEEMGFISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNAFG
AWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKEENLDNLKLPTFLNIFHDTVVASAT
LMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQAFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGS
FPAVDVAASYGFGSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWKAAVALSFISG
ILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLVCIFLLAIPQLQFAKAKDKEAYYRGEAQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active- transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3037

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ulaA family [H]

Homologues:

Organism=Escherichia coli, GI87082388, Length=451, Percent_Identity=39.689578713969, Blast_Score=308, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: 2.7.1.69

Molecular weight: Translated: 51153; Mature: 51153

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAGFVKATVGYLILNVGAGGL
CEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
VTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGFISVATTALLIGFGVNILLVA
HHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNAFGAWAVGIICGLYWAISSNMTV
HHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKEENLDNLKLPTFLNIFHDTVVASAT
EHHHHHCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQAFFMYILQTSLTFSVYLFILMQGVRM
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSELTNAFQGISSKLLPGSFPAVDVAASYGFGSSNAVLSGFAFGLIGQLITIALLVIFK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NPILIITGFVPVFFDNAAIAVYADKRGGWKAAVALSFISGILQVALGAVAVGLLGLTGGY
CCEEEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGNIDLVLPWLPFGYLFKFLGIAGYVLVCIFLLAIPQLQFAKAKDKEAYYRGEAQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAGFVKATVGYLILNVGAGGL
CEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
VTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGFISVATTALLIGFGVNILLVA
HHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNAFGAWAVGIICGLYWAISSNMTV
HHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKEENLDNLKLPTFLNIFHDTVVASAT
EHHHHHCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQAFFMYILQTSLTFSVYLFILMQGVRM
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSELTNAFQGISSKLLPGSFPAVDVAASYGFGSSNAVLSGFAFGLIGQLITIALLVIFK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NPILIITGFVPVFFDNAAIAVYADKRGGWKAAVALSFISGILQVALGAVAVGLLGLTGGY
CCEEEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGNIDLVLPWLPFGYLFKFLGIAGYVLVCIFLLAIPQLQFAKAKDKEAYYRGEAQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]