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The map label for this gene is engD [H]

Identifier: 15674254

GI number: 15674254

Start: 3480

End: 4595

Strand: Direct

Name: engD [H]

Synonym: SPy_0006

Alternate gene names: 15674254

Gene position: 3480-4595 (Clockwise)

Preceding gene: 15674253

Following gene: 15674255

Centisome position: 0.19

GC content: 37.19

Gene sequence:

>1116_bases
ATGGCTTTAACAGCAGGTATTGTAGGCTTACCAAATGTTGGTAAATCAACCTTATTTAACGCAATTACAAAAGCAGGAGC
AGAAGCTGCTAATTATCCTTTTGCGACTATTGATCCCAATGTTGGTATGGTAGAGGTTCCAGATGAGCGTCTGCAAAAAT
TGACAGAATTGATTACACCTAAAAAAACAGTTCCGACAACCTTTGAATTTACTGATATTGCAGGTATCGTTAAAGGTGCT
TCTAGAGGGGAAGGTCTAGGAAATAAATTTTTAGCTAATATTCGTGAAATCGATGCTATTGTTCATGTGGTACGTGCTTT
TGATGATGAAAATGTCATGCGTGAACAAGGTCGTGAGGATGCTTTCGTTGATCCTATAGCAGATATTGACACTATTAATC
TTGAATTAATCTTAGCTGATTTAGAGTCAATCAATAAACGTTATGCGCGTGTTGAAAAAATGGCACGAACTCAAAAAGAT
AAAGAATCAGTAGCAGAGTTTAATGTTTTGCAAAAGATTAAACCTGTTTTGGAAGATGGGAAATCAGCTAGGACAATTGA
GTTTACAGAAGATGAAGCAAAAGTTGTTAAAGGTCTCTTTTTATTAACAACTAAACCTGTTTTATATGTAGCTAATGTCG
ATGAAGATAAAGTTGCTAATCCAGATGGTATTGATTATGTCAAACAAATTCGTGACTTTGCAGCTACTGAAAATGCTGAA
GTAGTTGTTATCTCAGCGCGTGCAGAAGAAGAAATTTCAGAGCTTGACGATGAGGATAAAGAAGAATTTTTGGAAGCTAT
CGGTCTTACTGAATCAGGCGTTGATAAATTAACCAGAGCAGCTTATCATCTCTTAGGCCTTGGAACCTATTTTACAGCAG
GTGAAAAAGAGGTTCGTGCTTGGACGTTTAAGCGTGGTATAAAAGCTCCACAAGCTGCTGGTATTATCCATTCAGATTTT
GAAAGAGGTTTTATTCGTGCAGTAACCATGTCTTATGATGATCTAATGACCTACGGTTCAGAAAAAGCCGTCAAAGAAGC
TGGACGCTTGCGTGAAGAAGGAAAAGAATATGTTGTCCAAGATGGGGACATCATGGAATTCAGATTTAATGTGTAA

Upstream 100 bases:

>100_bases
AATGATAAGCAAATCTGAAATTTTCTTCTTATTCATACCGCTTTTTCTTCTATTTTTTGGTATAATAATCTTGATTGAAA
TTTGAATGGAGATTCGCTAA

Downstream 100 bases:

>100_bases
TTATATTAAAACAATATCAGAAGGTTGGAAGAACATTCCAGCCCTTTTGGCATTTTAGAAAGAGAAAATATGGTAAAAAT
GATTGTTGGTCTGGGAAATC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGA
SRGEGLGNKFLANIREIDAIVHVVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKVANPDGIDYVKQIRDFAATENAE
VVVISARAEEEISELDDEDKEEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDF
ERGFIRAVTMSYDDLMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV

Sequences:

>Translated_371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGA
SRGEGLGNKFLANIREIDAIVHVVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKVANPDGIDYVKQIRDFAATENAE
VVVISARAEEEISELDDEDKEEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDF
ERGFIRAVTMSYDDLMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV
>Mature_370_residues
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGAS
RGEGLGNKFLANIREIDAIVHVVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKDK
ESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKVANPDGIDYVKQIRDFAATENAEV
VVISARAEEEISELDDEDKEEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFE
RGFIRAVTMSYDDLMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=382, Percent_Identity=42.1465968586387, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1787454, Length=371, Percent_Identity=53.3692722371968, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789574, Length=145, Percent_Identity=28.2758620689655, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=41.0810810810811, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=383, Percent_Identity=41.5143603133159, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=386, Percent_Identity=35.7512953367876, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=248, Percent_Identity=31.4516129032258, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640873, Length=374, Percent_Identity=40.9090909090909, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640877, Length=374, Percent_Identity=40.9090909090909, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640875, Length=374, Percent_Identity=40.9090909090909, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640879, Length=333, Percent_Identity=38.7387387387387, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24585318, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41095; Mature: 40964

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITP
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREIDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
AFVDPIADIDTINLELILADLESINKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKVANPDGIDYVKQIRDFAATENAE
CCCEEEEECCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKEEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDDLMTYGSEKAVKEAGRLREEGKEYVVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCEEEC
DGDIMEFRFNV
CCCEEEEEECC
>Mature Secondary Structure 
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITP
CCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREIDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
AFVDPIADIDTINLELILADLESINKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKVANPDGIDYVKQIRDFAATENAE
CCCEEEEECCHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKEEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDDLMTYGSEKAVKEAGRLREEGKEYVVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCEEEC
DGDIMEFRFNV
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]