Click here to switch to the map view.

The map label for this gene is sunL

Identifier: 15673871

GI number: 15673871

Start: 1957830

End: 1959104

Strand: Reverse

Name: sunL

Synonym: L141260

Alternate gene names: 15673871

Gene position: 1959104-1957830 (Counterclockwise)

Preceding gene: 15673872

Following gene: 30024059

Centisome position: 82.82

GC content: 36.0

Gene sequence:

>1275_bases
ATGACAAAAAATGCAAGACAAACCGCACTCGATGTATTGAATGACATTTTTGGCAATGATGCTTATGCCAATATTTCATT
GGATCGAAATTTGCGAGATTCTGAACTATCCACAGTTGATAAAGCTTTTGTGACTGCCCTTGTATATGGAGTGGTTTCTA
AAAAGGATTTATTGGAGTGGCATATTACTCCCTTCTTGAAAAAAGAACCAAAACCTTGGGCAAAAATGCTCCTATTGCTT
ACAGTTTATCAAATCTTATTCATGGATAAGGTCCCAACTTCGGCAGCAGTAGATGAAGCAGTCAAAATCGCTAAACGTCG
TGATGGTCAAGCGACGGCTAACTTTATCAATGCTGTGTTACGTAATTTCATGCGTTCTGAACATCGAAATGAAGAACCAA
AGGATTGGGAAACAAAATATTCAATGCCCAAACTTTTATTGGATAAAATGGTTCGTCAATTTGGTGGAAAAAGAACAGGA
GAAATTTTAGAAAGTCTTGAAAAGCCAAGTCACGTTAGCTTACGAAAAATTGACCCAACCGTAGAAATTTCAGGAACTCG
TGCTTCTCTACTAACAGAAAGTGCTCTAATTGCTGACAGTGGAAATTTTGCAATGACAGAAGAATTTCAATCTGGCAGAA
TTACGATTCAAGATGAAACAAGTCAATTAGTTGCCCCTCAACTTGATTTAGAAGGAACAGAAGAAGTTCTTGACGCTTGT
GCAGCTCCTGGTGGTAAAAGTACTCATATGGCTCAATATTTAACAATTGGCCATATCACAGCACTAGATTTATATGATCA
TAAACTTGATTTAATTAATCAAAATGCAGAGCGTCAACATGTTGCGGATAAAATTACTACTCAAAAAGCCGATGCGACAA
TGATTTTTGAAGAATTTGGTTCAGATAAATTTGACCGAATTCTTGTGGACGCTCCGTGTTCAGGTATTGGATTAATTCGA
CGCAAACCAGATATTCGCTATAGAAAAGAAAGTTCGGATTTTGTCGATTTACAAAAAATTCAGCTAGAAATTCTGAACAG
CGCCTCGAAAAGCCTGAAAAAAAGTGGTATAATGGTATACAGTACTTGTACAATTTTTGATGAAGAGAACTTTGACGTTG
TTCGTCAATTTCTAGAAAGTCATCCTAATTTTGAACAAGTTGAAATTTCTAGCGATAAGGCAGATATGATTAAAGAAGGA
TGTATTTTTATTACTCCAGAAATGTATCATACAGATGGCTTTTTCATCGCGAAATTTAAGAAAATAGGCGAATAA

Upstream 100 bases:

>100_bases
ACAAAAGAATCATGAAAAGAGAGTGTTTTTAAGAAATTTAAGGAAAATCATCTGACGAAAGTCATTGACAGTCATTGACT
ACTAAGGGTATAATAGCTCT

Downstream 100 bases:

>100_bases
CTGCTGACAAATATTTTTTTTAATTCTGTCAGTAATTTTTAGACCTAAAAATAAAACTTTATTCTTGTTAAGGAGAAAAA
GTGGAATACAGTATTTTATC

Product: rRNA methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKAFVTALVYGVVSKKDLLEWHITPFLKKEPKPWAKMLLLL
TVYQILFMDKVPTSAAVDEAVKIAKRRDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTG
EILESLEKPSHVSLRKIDPTVEISGTRASLLTESALIADSGNFAMTEEFQSGRITIQDETSQLVAPQLDLEGTEEVLDAC
AAPGGKSTHMAQYLTIGHITALDLYDHKLDLINQNAERQHVADKITTQKADATMIFEEFGSDKFDRILVDAPCSGIGLIR
RKPDIRYRKESSDFVDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVRQFLESHPNFEQVEISSDKADMIKEG
CIFITPEMYHTDGFFIAKFKKIGE

Sequences:

>Translated_424_residues
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKAFVTALVYGVVSKKDLLEWHITPFLKKEPKPWAKMLLLL
TVYQILFMDKVPTSAAVDEAVKIAKRRDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTG
EILESLEKPSHVSLRKIDPTVEISGTRASLLTESALIADSGNFAMTEEFQSGRITIQDETSQLVAPQLDLEGTEEVLDAC
AAPGGKSTHMAQYLTIGHITALDLYDHKLDLINQNAERQHVADKITTQKADATMIFEEFGSDKFDRILVDAPCSGIGLIR
RKPDIRYRKESSDFVDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVRQFLESHPNFEQVEISSDKADMIKEG
CIFITPEMYHTDGFFIAKFKKIGE
>Mature_423_residues
TKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKAFVTALVYGVVSKKDLLEWHITPFLKKEPKPWAKMLLLLT
VYQILFMDKVPTSAAVDEAVKIAKRRDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGE
ILESLEKPSHVSLRKIDPTVEISGTRASLLTESALIADSGNFAMTEEFQSGRITIQDETSQLVAPQLDLEGTEEVLDACA
APGGKSTHMAQYLTIGHITALDLYDHKLDLINQNAERQHVADKITTQKADATMIFEEFGSDKFDRILVDAPCSGIGLIRR
KPDIRYRKESSDFVDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVRQFLESHPNFEQVEISSDKADMIKEGC
IFITPEMYHTDGFFIAKFKKIGE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=355, Percent_Identity=30.7042253521127, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI76150623, Length=355, Percent_Identity=30.7042253521127, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI32698918, Length=181, Percent_Identity=35.3591160220994, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI11545785, Length=237, Percent_Identity=29.957805907173, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI301336155, Length=196, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI39995082, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI2367212, Length=406, Percent_Identity=29.5566502463054, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87081985, Length=234, Percent_Identity=30.3418803418803, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=327, Percent_Identity=27.82874617737, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534021, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25143471, Length=209, Percent_Identity=30.622009569378, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=202, Percent_Identity=29.2079207920792, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI22024126, Length=241, Percent_Identity=29.045643153527, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24668781, Length=236, Percent_Identity=29.2372881355932, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356513, Length=236, Percent_Identity=29.2372881355932, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355201, Length=199, Percent_Identity=29.1457286432161, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356579, Length=230, Percent_Identity=29.5652173913043, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920494, Length=218, Percent_Identity=24.7706422018349, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47875; Mature: 47744

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKAFVTALVYGVVSKKDLLEW
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
HITPFLKKEPKPWAKMLLLLTVYQILFMDKVPTSAAVDEAVKIAKRRDGQATANFINAVL
HCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGEILESLEKPSHVSLRKIDPT
HHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCC
VEISGTRASLLTESALIADSGNFAMTEEFQSGRITIQDETSQLVAPQLDLEGTEEVLDAC
EEECCCHHHHHHHHHHEECCCCEEEECCCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHH
AAPGGKSTHMAQYLTIGHITALDLYDHKLDLINQNAERQHVADKITTQKADATMIFEEFG
CCCCCCCHHHHHHHHHHCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHC
SDKFDRILVDAPCSGIGLIRRKPDIRYRKESSDFVDLQKIQLEILNSASKSLKKSGIMVY
CCCHHEEEEECCCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
STCTIFDEENFDVVRQFLESHPNFEQVEISSDKADMIKEGCIFITPEMYHTDGFFIAKFK
EEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCEEECCCEEECCCEEEEHHH
KIGE
HHCC
>Mature Secondary Structure 
TKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKAFVTALVYGVVSKKDLLEW
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
HITPFLKKEPKPWAKMLLLLTVYQILFMDKVPTSAAVDEAVKIAKRRDGQATANFINAVL
HCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGEILESLEKPSHVSLRKIDPT
HHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCC
VEISGTRASLLTESALIADSGNFAMTEEFQSGRITIQDETSQLVAPQLDLEGTEEVLDAC
EEECCCHHHHHHHHHHEECCCCEEEECCCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHH
AAPGGKSTHMAQYLTIGHITALDLYDHKLDLINQNAERQHVADKITTQKADATMIFEEFG
CCCCCCCHHHHHHHHHHCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHC
SDKFDRILVDAPCSGIGLIRRKPDIRYRKESSDFVDLQKIQLEILNSASKSLKKSGIMVY
CCCHHEEEEECCCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
STCTIFDEENFDVVRQFLESHPNFEQVEISSDKADMIKEGCIFITPEMYHTDGFFIAKFK
EEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCEEECCCEEECCCEEEEHHH
KIGE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]