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The map label for this gene is trmH

Identifier: 15673854

GI number: 15673854

Start: 1941471

End: 1942199

Strand: Reverse

Name: trmH

Synonym: L0330

Alternate gene names: 15673854

Gene position: 1942199-1941471 (Counterclockwise)

Preceding gene: 30024057

Following gene: 15673853

Centisome position: 82.1

GC content: 36.63

Gene sequence:

>729_bases
ATGGAAAATACAGATTTGATTTACGGACTACATGCGGTCACGGAAGCTTTAAATGGAGACCTTGTCAACAAACTTTACGT
TCAAGAAGATTTACGTGGTAAAAATGTTGAAAAAATAAAAGAATTAGCACGACTTAAAAAAGTTAATATTTCATGGACAC
CCAAAACAGAATTAAATAAATTAACAGAAAACGGTGTTCACCAAGGCTTTATGGCAAGAGTGTCCGAATTTGCTTATGCA
GATTTAGAAAAGATTCTCCCAGCATTAGCCGAGAAATCTGATGCCACAATTTTAATTTTAGATGAGTTAACAGATCCTCA
TAATTTAGGGTCAATTGCTCGGACAGCTGATGCTACAGGAGTCGATGCAATTATTATTCCTAAACACCGAGCCGTTGGAA
TTACTTCAACGGCTGTCAAAGCTTCAACAGGTGCTTTACAACACGTCCCTATTGTCCGTGTTACTAATCTTTCTCAGACC
TTGGATAAACTTAAAGCTGCTAATTTCTGGGTTTTTGGGACGGACATGGACGGCACAGTTTACAGTAAGTGGAATACCAA
AGGTAAAGTTGCCTTGATTATCGGAAATGAAGGACATGGAATTGGTCAAAATCTCAAAAAACAAGTTGATGAAATGATTA
CAATTCCAATGACAGGACACGTTCAAAGTTTAAATGCATCAGTAGCAGCAAGTATTTTGATGTACGAAATTTTTAGAAAT
CGACTATAA

Upstream 100 bases:

>100_bases
GAACTTTTGGTGTTTTACATAATTTTTTTGTCAGATACATAATGAGCCAGAGTAACGAATTGAGTCAGGTTTTTTTGTCT
AAAAATGATATAATGATTTC

Downstream 100 bases:

>100_bases
AAAATACTGATGAAAGCTTTAGCGCTTGGAATCATTAAAGCCCAAACTTATGATTAATCTGTCAGTAAATTCAAGATATT
ATCAGCAAGTTGAAACAGCA

Product: tRNA-guanosine methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLEKILPALAEKSDATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQT
LDKLKAANFWVFGTDMDGTVYSKWNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEIFRN
RL

Sequences:

>Translated_242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLEKILPALAEKSDATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQT
LDKLKAANFWVFGTDMDGTVYSKWNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEIFRN
RL
>Mature_242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLEKILPALAEKSDATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQT
LDKLKAANFWVFGTDMDGTVYSKWNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEIFRN
RL

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=262, Percent_Identity=25.1908396946565, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1790623, Length=245, Percent_Identity=36.734693877551, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1790083, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788935, Length=146, Percent_Identity=28.0821917808219, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=257, Percent_Identity=29.5719844357977, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193204953, Length=143, Percent_Identity=28.6713286713287, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324775, Length=286, Percent_Identity=29.020979020979, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26515; Mature: 26515

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKVNISWTPKTELNK
CCCCCEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHH
LTENGVHQGFMARVSEFAYADLEKILPALAEKSDATILILDELTDPHNLGSIARTADATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHCCCCC
VDAIIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQTLDKLKAANFWVFGTDMDGTV
CCEEEECCCCEECCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEEECCCCCEE
YSKWNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEIFRN
EEEECCCCEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RL
CC
>Mature Secondary Structure
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKVNISWTPKTELNK
CCCCCEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHH
LTENGVHQGFMARVSEFAYADLEKILPALAEKSDATILILDELTDPHNLGSIARTADATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHCCCCC
VDAIIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQTLDKLKAANFWVFGTDMDGTV
CCEEEECCCCEECCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEEECCCCCEE
YSKWNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEIFRN
EEEECCCCEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA