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The map label for this gene is aspB

Identifier: 15673812

GI number: 15673812

Start: 1896787

End: 1897968

Strand: Reverse

Name: aspB

Synonym: L0098

Alternate gene names: 15673812

Gene position: 1897968-1896787 (Counterclockwise)

Preceding gene: 15673813

Following gene: 15673811

Centisome position: 80.23

GC content: 37.39

Gene sequence:

>1182_bases
ATGAAAAAAAATTCTGATTTTGTATTAAAAATGGATGAGTCCGTCACTCTTGCTGCGGCAAATCGCGCAAAAGCATTAAA
AGCACAAGGGCGAGATATTATTGACCTGACACTTGGTCAGCCAGACTTTCCAACACCAAAAATAATTGGTCAAGCAGCTA
TTGAAGCAATCGATAATGGCAAGGCGAGCTTTTATACACAAGCTGGTGGACTTCCAGAATTAAAAAATGCAGTTCAACAT
TATTGGACGCGTTTTTATAATTATGAAATTCAACCAAATGAAATATTGATTACAGCTGGAGCAAAGTTTGCCCTTTATGC
TTACTTTATGGCAACTGTTGACCCTGACGATGAGGTAATCATTCCTGCTCCTTACTGGGTTTCTTATGTTGACCAAGTGA
AAATGGCTGGAGGAAATCCGGTAATTGTAGAAGCCAAGCAAGAGAATAATTTTAAAGTTACGGTTGAGCAATTAGAAGAA
GCAAGAACAAGTAAAAGTAAAATTTTATTACTCAATTCACCTTCTAATCCAACAGGAATGATTTATTCTAAAGAAGAATT
AACAGCCATTGGAGAGTGGGCTCTTGCTCATGATTTATTAATTTTGGCAGATGATATTTATCATCGTTTAGTTTATAATG
GAGCGGAATTTACAGCAATTTCAAGTCTATCTGATGAAATTCGGAAAAGAACGACAGTGATTAATGGTGTTTCTAAAACA
TTTGCAATGACTGGTTGGCGGATTGGACTAGCTGTAGGTGATCCAGAAATTATTTCTGCGATGACTAAGATTGCGAGCCA
AACGACTTCTAATCCAACTGCTGTCGCTCAATACGCAGCAATAGAAGCTTTTGAAGAAAGAGATAATAGTTTTGAGATAA
TGCATGCAGCATTTGAAGAACGTTTAAATATCATTTATGGTCAACTTTCTGAGGTTCCAGGATTTGAACTTGTAAAACCA
AATGGTGCTTTCTATTTATTCCCGAAAGTGACTAAGGCAATGGCGATGAAAGGCTATAGTGATGTGACTGATTTTACAAC
TGCTATTCTTGAAGAAGCAGGTGTAGCCTTGGTTACAGGAGCAGGTTTTGGTTCGCCAGAAAATGTGCGCCTGAGCTATG
CAACAAGTCTTAAAAATTTAGAAGTTGCAGTGGCACGTTTAAAAGATTGGATGAATGAATGA

Upstream 100 bases:

>100_bases
AATCAGTTGTCTTAGCGCTTTACAAAGGGAAACCGGCTTGGGAAGTAAATAATAGCAATGGTTTTAAAGTTTATGACTTT
GAGTCAGGAAAAGAGTTGAT

Downstream 100 bases:

>100_bases
TCGATAAGAAAGAAGCAAAATCGGCCTATAAACTTTCAAAAAAAGTTGGAGCAGTTGTTGCTTATAAGAATCTCGAAACG
AATGAACGCTATATTGATAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKNSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKIIGQAAIEAIDNGKASFYTQAGGLPELKNAVQH
YWTRFYNYEIQPNEILITAGAKFALYAYFMATVDPDDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEE
ARTSKSKILLLNSPSNPTGMIYSKEELTAIGEWALAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRKRTTVINGVSKT
FAMTGWRIGLAVGDPEIISAMTKIASQTTSNPTAVAQYAAIEAFEERDNSFEIMHAAFEERLNIIYGQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYSDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLKNLEVAVARLKDWMNE

Sequences:

>Translated_393_residues
MKKNSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKIIGQAAIEAIDNGKASFYTQAGGLPELKNAVQH
YWTRFYNYEIQPNEILITAGAKFALYAYFMATVDPDDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEE
ARTSKSKILLLNSPSNPTGMIYSKEELTAIGEWALAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRKRTTVINGVSKT
FAMTGWRIGLAVGDPEIISAMTKIASQTTSNPTAVAQYAAIEAFEERDNSFEIMHAAFEERLNIIYGQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYSDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLKNLEVAVARLKDWMNE
>Mature_393_residues
MKKNSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKIIGQAAIEAIDNGKASFYTQAGGLPELKNAVQH
YWTRFYNYEIQPNEILITAGAKFALYAYFMATVDPDDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEE
ARTSKSKILLLNSPSNPTGMIYSKEELTAIGEWALAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRKRTTVINGVSKT
FAMTGWRIGLAVGDPEIISAMTKIASQTTSNPTAVAQYAAIEAFEERDNSFEIMHAAFEERLNIIYGQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYSDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLKNLEVAVARLKDWMNE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=346, Percent_Identity=28.3236994219653, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881279, Length=346, Percent_Identity=28.3236994219653, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713254, Length=317, Percent_Identity=28.391167192429, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI56713256, Length=317, Percent_Identity=28.391167192429, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=23.1958762886598, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI169881281, Length=253, Percent_Identity=26.8774703557312, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI149944424, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788722, Length=351, Percent_Identity=27.3504273504274, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786816, Length=370, Percent_Identity=24.8648648648649, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788627, Length=391, Percent_Identity=26.3427109974425, Blast_Score=128, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=409, Percent_Identity=27.8728606356968, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=409, Percent_Identity=27.8728606356968, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=27.020202020202, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=24.331550802139, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=22.7027027027027, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=26.9922879177378, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320317, Length=370, Percent_Identity=23.5135135135135, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=342, Percent_Identity=23.6842105263158, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=28.0927835051546, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=28.0927835051546, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=28.0927835051546, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=28.0927835051546, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=358, Percent_Identity=24.8603351955307, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641770, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641760, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641768, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641766, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641764, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45551451, Length=377, Percent_Identity=22.5464190981432, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43228; Mature: 43228

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKIIGQAAIEAIDNG
CCCCCCEEEEECCCEEEEECCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
KASFYTQAGGLPELKNAVQHYWTRFYNYEIQPNEILITAGAKFALYAYFMATVDPDDEVI
CCEEEECCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCHHHEEEEEHEEECCCCCEE
IPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEEARTSKSKILLLNSPSNPTGM
ECCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCEE
IYSKEELTAIGEWALAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRKRTTVINGVSKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHH
FAMTGWRIGLAVGDPEIISAMTKIASQTTSNPTAVAQYAAIEAFEERDNSFEIMHAAFEE
HEECCEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLNIIYGQLSEVPGFELVKPNGAFYLFPKVTKAMAMKGYSDVTDFTTAILEEAGVALVTG
HHHHHHHHHHCCCCCEEECCCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEE
AGFGSPENVRLSYATSLKNLEVAVARLKDWMNE
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKNSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKIIGQAAIEAIDNG
CCCCCCEEEEECCCEEEEECCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
KASFYTQAGGLPELKNAVQHYWTRFYNYEIQPNEILITAGAKFALYAYFMATVDPDDEVI
CCEEEECCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCHHHEEEEEHEEECCCCCEE
IPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEEARTSKSKILLLNSPSNPTGM
ECCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCEE
IYSKEELTAIGEWALAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRKRTTVINGVSKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHH
FAMTGWRIGLAVGDPEIISAMTKIASQTTSNPTAVAQYAAIEAFEERDNSFEIMHAAFEE
HEECCEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLNIIYGQLSEVPGFELVKPNGAFYLFPKVTKAMAMKGYSDVTDFTTAILEEAGVALVTG
HHHHHHHHHHCCCCCEEECCCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEE
AGFGSPENVRLSYATSLKNLEVAVARLKDWMNE
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]