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The map label for this gene is rpoB

Identifier: 15673782

GI number: 15673782

Start: 1860915

End: 1864505

Strand: Reverse

Name: rpoB

Synonym: L0137

Alternate gene names: 15673782

Gene position: 1864505-1860915 (Counterclockwise)

Preceding gene: 15673783

Following gene: 15673781

Centisome position: 78.82

GC content: 41.21

Gene sequence:

>3591_bases
TTGGCAGGACATGACGTAAAATACGGTAAACACCGTACAAGACGCAGTTTTTCACGTATTAAAGAAGTAATCGGTTTGCC
AAACCTCATCGAAGTTCAAACATTAAGTTATAAAAACTTCCTCGATGAAGGTCTTGCAAATGTCTTCAAAGAAATGTTTC
CAATCGACAACTTTGCGGGTACAATGGAACTCGAATTTGTTGGTTATGAAATGAAAACCCCAAAATACACTGTTGAAGAA
GCTCGCGCACATGACGCAAACTATTCAGCACCTATCTATGTAACCTTCCGTCTTGTAAATAAAGAAACTGGTGAATTAAA
AACACAAGAAGTCTTCTTTGGTGACTTCCCACTCATGACTGAAATGGGGACATTTATCAATAACGGTTCAGAACGTTTGA
TCGTTAGCCAATTGGTACGTAGTCCTGGTTCATACTTCCATCTTAAAGCTGATAAAAACGGTCTTGAAAGTTTTGGACAT
ACAACCATTCCTAACCGTGGAGCTTGGTTTGAGTTAGATACAGATGCTAAAGGCATTGGTTATGTTCGTATTGACCGTAC
ACGTAAATTAACTTTTACAACTATGCTTCGTGCGCTTGGATTTGGTTCAGATGAAGAAATCCTTGAATTGTTGGGCGAAA
CTCAACTTTTAACAGACACTATTGCAAAAGATGTTCATAAAAACCCAGCTGACACGCGTGTAGAAGAAGCGCTCAAAGAC
ATCTATGACCGCTTGCGTCCAGGAGAACCTAAAACAGCAGATAGCTCACGTGGCTTGCTTGTTGCTCGTTTCTTCGATCC
AAAACGTTATGACTTCGCACCTGTTGGACGTTACAAATTTAACAAGAAATTAGCGCTTAAAAATCGTTTGCTTGGTTTGA
CTTTGGCTGAACCAATTGTTGACCCAGAAACTGGTGAAATTCTTGTTAATACAGATACTCTTGTTACTCGTGATGTGCTT
GATTTAATCGAACCATTGCTTGATAACGGTCTTGGAAACTTTGTTGTTGAACCATCTGACGACGCTGTAATTCCAGAACC
AATTACTTTGCAAAGTATCAAAGTTTATTCACCTAAAGATCCAGAACGTGTTGTTACATTGCTCTCAAATGGTAATCCTG
ATGCAGAATGCCGTGTCTTGACACCAGCCGATGTGATTTCAAATATCAGCTACTGGCTTGGTCTTGCTGAAGGAATTGGT
AAAGTGGACGATATTGACCACTTAGGTAACCGTCGTATCCGTTCAGTAGGTGAATTGCTTCAAAACCAAGTACGTATCGG
ACTTTCACGTATGGAACGTGTTATTCGCGAACGTATGTCATCTTCAGAAAATGAAAACATCACACCGCAAGGTTTGATTA
ACATTCGTCCTGTAACAGCTTCAATTAAAGAATTCTTTGGTTCATCACAATTGTCACAATTTATGGACCAACACAATCCT
TTATCTGAGCTTTCACACAAACGTCGTTTTTCTGCCTTAGGACCTGGTGGTATCTCACGTGACCGTGCTTCATATGAAGT
ACGTGACGTTCACTATACTCACTATGGCCGTATGTGTCCTATTGAAACACCTGAAGGACCAAACATCGGTTTGATTAACA
ACTTGTCATCATATGCCAAAGTAAACGAATATGGTTTCATCATGTCACCATACCGTCGTGTTGACCGTGTGAATGGTGTG
GTTACTGACGAAGTTGAATATTTAACTGCCGATGAAGAAGACAACTATACTGTTGCCCAAGCAAACTCACCATTGACTGA
AGATAGCCGCTTTGCTAACGAAACAGTTATGGCTCGTCATACTGGTAACAATATTGAAGTTGAAGCTTCAACAGCAGACT
ATATGGACGTTTCACCTAAACAGGTTATCGCCGTTGCTGCTGCATGTATTCCATTCTTGGAAAACGATGACTCCAACCGT
GCCCTCATGGGTGCCAACATGCAACGTCAAGCAGTTCCATTGATTGACCCACATGCACCTTGGATTGGTACTGGTATGGA
ACATCAAACTGCTCGTGACTCAGGTGCTGCGCTTATTGCAAAACATGCTGGTGTTGTTGAGTATGTTGATGGTAATGAAA
TTCGTGTTCGTCGTACTTCTGGTGAACTAGATATTTACAATATTACAAAATATCGTCGTTCAAACTCAGGAACTTCTTAT
AACCAACGTCCATTGGCTCGACTTGGAGAAAAAGTTGAGAAAGGGGACATCATTGCTGATGGACCTTCTATGGAAAATGG
AGAAATGGCCCTTGGTCAAAATCCACTTGTTGCCTATATGACTTGGGAAGGTTATAACTTCGAGGATGCGGTAATCATGT
CAGAACGTTTGATTAAAGACGACGTTTATACATCAATTGCCATCGAAGAATATGAATCAGAAACACGCGATACAAAACTT
GGCCCTGAAGAAATTACTCGTGAAATTCCAAACGTTGGGGATGAAGCACTCAAAAACCTTGATGAATCAGGAATTATCCG
TATTGGTGCTGAAGTTAAAGATGGCGACTTGCTTGTTGGTAAAGTAACCCCTAAAGGTGAAACTGATCCAACACCAGAAG
AACGTTTGCTTCGTGCAATCTTTGGTGAAAAAGCTCGTGAAGTTCGTGATACATCACTTCGTGTTCCTCACGGAGGTGGC
GGTATTGTTCATGACGTTCGTGTATTTACACGCGAAAATGGTGATGAATTGCCATCAGGTGTGAATAAACTTGTTCGCGT
CTTCATTGCTCAAAAACGTAAGATTCACGTTGGGGATAAAATGGCCGGACGTCATGGTAATAAAGGGGTTGTTTCAAATA
TCGTTCCAATGGAAGATATGCCTTACTTACCAGATGGTACACCTATTGATATCATGTTGAACCCACTTGGGGTACCATCA
CGTATGAATATCGGACAAGTTATGGAGCTCCATTTAGGTATGGCTGCTCGTACACTTGGAATTCACATTGCAACTCCAGT
GTTTGATGGAGCATCTGATGAAGATATCTGGGATACCGTTAAAGAAGCTGGAATGGCTGATGATGCGAAAACAGTCCTTT
ATGACGGACGTACTGGTGAACCATTTGATAACCGAATTTCAGTCGGTGTCATGTACATGATTAAACTTCACCACATGGTT
GATGATAAACTCCATGCTCGTTCAGTTGGTCCTTACTCACTCGTTACACAACAACCGCTCGGTGGTAAAGCGCAGTTCGG
TGGACAACGTTTTGGGGAAATGGAAGTTTGGGCACTTGAAGCCTATGGTGCTGCCAATGTTCTTCAAGAAATCTTGACTT
ACAAATCAGATGACGTGATTGGACGTACGCGCGCTTATGAAGCTATTGTTAAAGGTGAACGTATTCCTAAACCAGGTCTT
CCTGAATCATTCCGCGTATTGGTTAAAGAGTTACAATCACTTGGTCTTGATATGAAAGTCCTTGATGCTGACCGTAATGT
TCTTGACTTACGTGAATTGGATGAAGATGAAGTAATGACTCGTCCAGATAATACAGAAATTACTCCTGAAATGCTTGAAG
CACAGGAAGCTATTGTTGCACAAGCAGAAGCTGAAGAAGAAGCTTTGATTAACGCTGATACTGAAAAATAA

Upstream 100 bases:

>100_bases
ATAAAAAAGACAAACTACAGACTTTTCGGTTTTTTTAATTAAAAATTCATCAAAAACACAGACTTTTTTAATCAAATCTA
AAAAATAGAGGAGAAAACAC

Downstream 100 bases:

>100_bases
GATTTTGTAATTAATATTTTGAGATAGATTTACTGACAAAAATTTCTGTCAGTAAATCTCTAATCTCATAATCGTCTAGC
GTTAAATTTATTAGAAGTGG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1196; Mature: 1195

Protein sequence:

>1196_residues
MAGHDVKYGKHRTRRSFSRIKEVIGLPNLIEVQTLSYKNFLDEGLANVFKEMFPIDNFAGTMELEFVGYEMKTPKYTVEE
ARAHDANYSAPIYVTFRLVNKETGELKTQEVFFGDFPLMTEMGTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGH
TTIPNRGAWFELDTDAKGIGYVRIDRTRKLTFTTMLRALGFGSDEEILELLGETQLLTDTIAKDVHKNPADTRVEEALKD
IYDRLRPGEPKTADSSRGLLVARFFDPKRYDFAPVGRYKFNKKLALKNRLLGLTLAEPIVDPETGEILVNTDTLVTRDVL
DLIEPLLDNGLGNFVVEPSDDAVIPEPITLQSIKVYSPKDPERVVTLLSNGNPDAECRVLTPADVISNISYWLGLAEGIG
KVDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIRERMSSSENENITPQGLINIRPVTASIKEFFGSSQLSQFMDQHNP
LSELSHKRRFSALGPGGISRDRASYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYAKVNEYGFIMSPYRRVDRVNGV
VTDEVEYLTADEEDNYTVAQANSPLTEDSRFANETVMARHTGNNIEVEASTADYMDVSPKQVIAVAAACIPFLENDDSNR
ALMGANMQRQAVPLIDPHAPWIGTGMEHQTARDSGAALIAKHAGVVEYVDGNEIRVRRTSGELDIYNITKYRRSNSGTSY
NQRPLARLGEKVEKGDIIADGPSMENGEMALGQNPLVAYMTWEGYNFEDAVIMSERLIKDDVYTSIAIEEYESETRDTKL
GPEEITREIPNVGDEALKNLDESGIIRIGAEVKDGDLLVGKVTPKGETDPTPEERLLRAIFGEKAREVRDTSLRVPHGGG
GIVHDVRVFTRENGDELPSGVNKLVRVFIAQKRKIHVGDKMAGRHGNKGVVSNIVPMEDMPYLPDGTPIDIMLNPLGVPS
RMNIGQVMELHLGMAARTLGIHIATPVFDGASDEDIWDTVKEAGMADDAKTVLYDGRTGEPFDNRISVGVMYMIKLHHMV
DDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAANVLQEILTYKSDDVIGRTRAYEAIVKGERIPKPGL
PESFRVLVKELQSLGLDMKVLDADRNVLDLRELDEDEVMTRPDNTEITPEMLEAQEAIVAQAEAEEEALINADTEK

Sequences:

>Translated_1196_residues
MAGHDVKYGKHRTRRSFSRIKEVIGLPNLIEVQTLSYKNFLDEGLANVFKEMFPIDNFAGTMELEFVGYEMKTPKYTVEE
ARAHDANYSAPIYVTFRLVNKETGELKTQEVFFGDFPLMTEMGTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGH
TTIPNRGAWFELDTDAKGIGYVRIDRTRKLTFTTMLRALGFGSDEEILELLGETQLLTDTIAKDVHKNPADTRVEEALKD
IYDRLRPGEPKTADSSRGLLVARFFDPKRYDFAPVGRYKFNKKLALKNRLLGLTLAEPIVDPETGEILVNTDTLVTRDVL
DLIEPLLDNGLGNFVVEPSDDAVIPEPITLQSIKVYSPKDPERVVTLLSNGNPDAECRVLTPADVISNISYWLGLAEGIG
KVDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIRERMSSSENENITPQGLINIRPVTASIKEFFGSSQLSQFMDQHNP
LSELSHKRRFSALGPGGISRDRASYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYAKVNEYGFIMSPYRRVDRVNGV
VTDEVEYLTADEEDNYTVAQANSPLTEDSRFANETVMARHTGNNIEVEASTADYMDVSPKQVIAVAAACIPFLENDDSNR
ALMGANMQRQAVPLIDPHAPWIGTGMEHQTARDSGAALIAKHAGVVEYVDGNEIRVRRTSGELDIYNITKYRRSNSGTSY
NQRPLARLGEKVEKGDIIADGPSMENGEMALGQNPLVAYMTWEGYNFEDAVIMSERLIKDDVYTSIAIEEYESETRDTKL
GPEEITREIPNVGDEALKNLDESGIIRIGAEVKDGDLLVGKVTPKGETDPTPEERLLRAIFGEKAREVRDTSLRVPHGGG
GIVHDVRVFTRENGDELPSGVNKLVRVFIAQKRKIHVGDKMAGRHGNKGVVSNIVPMEDMPYLPDGTPIDIMLNPLGVPS
RMNIGQVMELHLGMAARTLGIHIATPVFDGASDEDIWDTVKEAGMADDAKTVLYDGRTGEPFDNRISVGVMYMIKLHHMV
DDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAANVLQEILTYKSDDVIGRTRAYEAIVKGERIPKPGL
PESFRVLVKELQSLGLDMKVLDADRNVLDLRELDEDEVMTRPDNTEITPEMLEAQEAIVAQAEAEEEALINADTEK
>Mature_1195_residues
AGHDVKYGKHRTRRSFSRIKEVIGLPNLIEVQTLSYKNFLDEGLANVFKEMFPIDNFAGTMELEFVGYEMKTPKYTVEEA
RAHDANYSAPIYVTFRLVNKETGELKTQEVFFGDFPLMTEMGTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGHT
TIPNRGAWFELDTDAKGIGYVRIDRTRKLTFTTMLRALGFGSDEEILELLGETQLLTDTIAKDVHKNPADTRVEEALKDI
YDRLRPGEPKTADSSRGLLVARFFDPKRYDFAPVGRYKFNKKLALKNRLLGLTLAEPIVDPETGEILVNTDTLVTRDVLD
LIEPLLDNGLGNFVVEPSDDAVIPEPITLQSIKVYSPKDPERVVTLLSNGNPDAECRVLTPADVISNISYWLGLAEGIGK
VDDIDHLGNRRIRSVGELLQNQVRIGLSRMERVIRERMSSSENENITPQGLINIRPVTASIKEFFGSSQLSQFMDQHNPL
SELSHKRRFSALGPGGISRDRASYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYAKVNEYGFIMSPYRRVDRVNGVV
TDEVEYLTADEEDNYTVAQANSPLTEDSRFANETVMARHTGNNIEVEASTADYMDVSPKQVIAVAAACIPFLENDDSNRA
LMGANMQRQAVPLIDPHAPWIGTGMEHQTARDSGAALIAKHAGVVEYVDGNEIRVRRTSGELDIYNITKYRRSNSGTSYN
QRPLARLGEKVEKGDIIADGPSMENGEMALGQNPLVAYMTWEGYNFEDAVIMSERLIKDDVYTSIAIEEYESETRDTKLG
PEEITREIPNVGDEALKNLDESGIIRIGAEVKDGDLLVGKVTPKGETDPTPEERLLRAIFGEKAREVRDTSLRVPHGGGG
IVHDVRVFTRENGDELPSGVNKLVRVFIAQKRKIHVGDKMAGRHGNKGVVSNIVPMEDMPYLPDGTPIDIMLNPLGVPSR
MNIGQVMELHLGMAARTLGIHIATPVFDGASDEDIWDTVKEAGMADDAKTVLYDGRTGEPFDNRISVGVMYMIKLHHMVD
DKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAANVLQEILTYKSDDVIGRTRAYEAIVKGERIPKPGLP
ESFRVLVKELQSLGLDMKVLDADRNVLDLRELDEDEVMTRPDNTEITPEMLEAQEAIVAQAEAEEEALINADTEK

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=846, Percent_Identity=25.7683215130024, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI238908505, Length=846, Percent_Identity=25.7683215130024, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI4505941, Length=416, Percent_Identity=31.25, Blast_Score=180, Evalue=9e-45,
Organism=Homo sapiens, GI33469941, Length=422, Percent_Identity=29.3838862559242, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI212286172, Length=422, Percent_Identity=29.3838862559242, Blast_Score=159, Evalue=2e-38,
Organism=Escherichia coli, GI1790419, Length=951, Percent_Identity=45.9516298633018, Blast_Score=779, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=438, Percent_Identity=30.8219178082192, Blast_Score=184, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17552304, Length=416, Percent_Identity=31.7307692307692, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17506623, Length=185, Percent_Identity=39.4594594594595, Blast_Score=125, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324725, Length=540, Percent_Identity=28.5185185185185, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324781, Length=406, Percent_Identity=31.0344827586207, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6325267, Length=360, Percent_Identity=31.3888888888889, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17647877, Length=413, Percent_Identity=31.4769975786925, Blast_Score=181, Evalue=4e-45,
Organism=Drosophila melanogaster, GI17136444, Length=417, Percent_Identity=30.4556354916067, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17136446, Length=365, Percent_Identity=30.1369863013699, Blast_Score=124, Evalue=5e-28,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_LACLA (Q9CEN6)

Other databases:

- EMBL:   AE005176
- PIR:   H86849
- RefSeq:   NP_267957.1
- ProteinModelPortal:   Q9CEN6
- GeneID:   1115465
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0137
- NMPDR:   fig|272623.1.peg.1846
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   LLAC272623:L0137-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 133155; Mature: 133024

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHDVKYGKHRTRRSFSRIKEVIGLPNLIEVQTLSYKNFLDEGLANVFKEMFPIDNFAG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
TMELEFVGYEMKTPKYTVEEARAHDANYSAPIYVTFRLVNKETGELKTQEVFFGDFPLMT
EEEEEEEEEEECCCCEEHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCHHH
EMGTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGHTTIPNRGAWFELDTDAKGIG
HHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCCEEEECCCCCCEE
YVRIDRTRKLTFTTMLRALGFGSDEEILELLGETQLLTDTIAKDVHKNPADTRVEEALKD
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
IYDRLRPGEPKTADSSRGLLVARFFDPKRYDFAPVGRYKFNKKLALKNRLLGLTLAEPIV
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCEEHHCCCC
DPETGEILVNTDTLVTRDVLDLIEPLLDNGLGNFVVEPSDDAVIPEPITLQSIKVYSPKD
CCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEECCCC
PERVVTLLSNGNPDAECRVLTPADVISNISYWLGLAEGIGKVDDIDHLGNRRIRSVGELL
HHHHEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHH
QNQVRIGLSRMERVIRERMSSSENENITPQGLINIRPVTASIKEFFGSSQLSQFMDQHNP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHHHHHHHCCCC
LSELSHKRRFSALGPGGISRDRASYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYAK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
VNEYGFIMSPYRRVDRVNGVVTDEVEYLTADEEDNYTVAQANSPLTEDSRFANETVMARH
HCCCCCEECHHHHHHHHCCEEECCEEEEECCCCCCEEEEECCCCCCCCHHHHCCEEEEEE
TGNNIEVEASTADYMDVSPKQVIAVAAACIPFLENDDSNRALMGANMQRQAVPLIDPHAP
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
WIGTGMEHQTARDSGAALIAKHAGVVEYVDGNEIRVRRTSGELDIYNITKYRRSNSGTSY
CCCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEECCCCEEEEEHHHHHCCCCCCCC
NQRPLARLGEKVEKGDIIADGPSMENGEMALGQNPLVAYMTWEGYNFEDAVIMSERLIKD
CCCHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHH
DVYTSIAIEEYESETRDTKLGPEEITREIPNVGDEALKNLDESGIIRIGAEVKDGDLLVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECEECCCCEEEE
KVTPKGETDPTPEERLLRAIFGEKAREVRDTSLRVPHGGGGIVHDVRVFTRENGDELPSG
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCEEEEEEEECCCCCCCHHH
VNKLVRVFIAQKRKIHVGDKMAGRHGNKGVVSNIVPMEDMPYLPDGTPIDIMLNPLGVPS
HHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
RMNIGQVMELHLGMAARTLGIHIATPVFDGASDEDIWDTVKEAGMADDAKTVLYDGRTGE
CCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCC
PFDNRISVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALE
CCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
AYGAANVLQEILTYKSDDVIGRTRAYEAIVKGERIPKPGLPESFRVLVKELQSLGLDMKV
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LDADRNVLDLRELDEDEVMTRPDNTEITPEMLEAQEAIVAQAEAEEEALINADTEK
ECCCCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEECCCCCC
>Mature Secondary Structure 
AGHDVKYGKHRTRRSFSRIKEVIGLPNLIEVQTLSYKNFLDEGLANVFKEMFPIDNFAG
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
TMELEFVGYEMKTPKYTVEEARAHDANYSAPIYVTFRLVNKETGELKTQEVFFGDFPLMT
EEEEEEEEEEECCCCEEHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCHHH
EMGTFINNGSERLIVSQLVRSPGSYFHLKADKNGLESFGHTTIPNRGAWFELDTDAKGIG
HHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCCEEEECCCCCCEE
YVRIDRTRKLTFTTMLRALGFGSDEEILELLGETQLLTDTIAKDVHKNPADTRVEEALKD
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
IYDRLRPGEPKTADSSRGLLVARFFDPKRYDFAPVGRYKFNKKLALKNRLLGLTLAEPIV
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCEEHHCCCC
DPETGEILVNTDTLVTRDVLDLIEPLLDNGLGNFVVEPSDDAVIPEPITLQSIKVYSPKD
CCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEECCCC
PERVVTLLSNGNPDAECRVLTPADVISNISYWLGLAEGIGKVDDIDHLGNRRIRSVGELL
HHHHEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHH
QNQVRIGLSRMERVIRERMSSSENENITPQGLINIRPVTASIKEFFGSSQLSQFMDQHNP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHHHHHHHCCCC
LSELSHKRRFSALGPGGISRDRASYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYAK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
VNEYGFIMSPYRRVDRVNGVVTDEVEYLTADEEDNYTVAQANSPLTEDSRFANETVMARH
HCCCCCEECHHHHHHHHCCEEECCEEEEECCCCCCEEEEECCCCCCCCHHHHCCEEEEEE
TGNNIEVEASTADYMDVSPKQVIAVAAACIPFLENDDSNRALMGANMQRQAVPLIDPHAP
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
WIGTGMEHQTARDSGAALIAKHAGVVEYVDGNEIRVRRTSGELDIYNITKYRRSNSGTSY
CCCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEECCCCEEEEEHHHHHCCCCCCCC
NQRPLARLGEKVEKGDIIADGPSMENGEMALGQNPLVAYMTWEGYNFEDAVIMSERLIKD
CCCHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHH
DVYTSIAIEEYESETRDTKLGPEEITREIPNVGDEALKNLDESGIIRIGAEVKDGDLLVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECEECCCCEEEE
KVTPKGETDPTPEERLLRAIFGEKAREVRDTSLRVPHGGGGIVHDVRVFTRENGDELPSG
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCEEEEEEEECCCCCCCHHH
VNKLVRVFIAQKRKIHVGDKMAGRHGNKGVVSNIVPMEDMPYLPDGTPIDIMLNPLGVPS
HHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
RMNIGQVMELHLGMAARTLGIHIATPVFDGASDEDIWDTVKEAGMADDAKTVLYDGRTGE
CCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCC
PFDNRISVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALE
CCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
AYGAANVLQEILTYKSDDVIGRTRAYEAIVKGERIPKPGLPESFRVLVKELQSLGLDMKV
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LDADRNVLDLRELDEDEVMTRPDNTEITPEMLEAQEAIVAQAEAEEEALINADTEK
ECCCCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471