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The map label for this gene is ysfC

Identifier: 15673776

GI number: 15673776

Start: 1852397

End: 1853728

Strand: Reverse

Name: ysfC

Synonym: L35751

Alternate gene names: 15673776

Gene position: 1853728-1852397 (Counterclockwise)

Preceding gene: 15673777

Following gene: 15673775

Centisome position: 78.36

GC content: 36.86

Gene sequence:

>1332_bases
ATGGTTGATACATTAAAAGAAATCCCCTTTGCACTTAAGTTCCTAATTGTTATTATTATCACTTTTGGTATCTCTGTGAT
TTTAACGCCAATTATGACTTTTGTGTCCAAAGCAATTGGTGCGGTGGACAAGCCTAACGAGCGTCGTGTGAATAAAAAAC
CAATGCCCTCTGCTGGAGGTTTGGTCATTTTCATTGCTTTTGCGATTGCGACCTTGTTTATTCTGCCACATATTGTTCAT
AACCAGCCTCCCATTCATTCGCAACCTCCAGTACATGGCGCAAGTCATCAGCCAATTCAGCTAGTCAGCTATTTTAGCTA
CATTTGGCCCTTTATTGTTGGTGCTGGAATTGTTGTTTTGACTGGTTTGATTGATGATATAAAAGAAATTTCACCTAAAA
TGAAACTTTTAGGATTGACAGTTGCGGCGAGTTTTATTTGGTTCTTTACCAACGCCCGCTTTGATAATTTAAAAATTCCT
TTCGGGGGGCCTTTACTAATCTTTCCTGCTTGGTTATCCTTTATTTTTACCGTTTTTTGGATACTTGCGATTACTAATGC
AATAAATTTAATTGACGGATTGGACGGACTAGCAAGTGGAGTATCAATTATTTCACTGACAACAATGGGAATTGTTTCTT
ACTTTTTCTTACCAAGTCCAAATGTATTTTTACCGATTACCATTTTTATAATGGTGGCTGCAATTATGGGATTCTTTCCT
TATAATTATCATCCAGCGATTATTTATCTGGGAGATACGGGAGCCCTATTCCTTGGTTTTATCATCTCGGTTGCTTCTTT
GCAAGGATTAAAGAATGCAACGGCTGTAGCCGTTTTGACTCCTTTACTAATTTTAGGAGTACCAATTACGGATACAATTA
TGGCAATGGTTCGTCGGAAACTTAATCGTCAATCGATTGCAACGGCTGATAAACGACATCTTCACCATCGCCTAATGGCA
CTTGGTTTTACTCATCGTGGAGCTGTTCTAGTCATTTATGGAATTGCATCAATATTTGCATTTATCTCCATTCTTTTGCA
ATTTTCAAGTCGTATCGGTGGGATTCTCTTAGTGATTGCTTGTCTCTTTGGATTGGAAATATTTATTGAACTTGTTGGAA
TTCTAGGCGAAAATCGGCAGCCAGTCTTAAAAGCACTGAAATTTGTTGGAAATTCTAGTTATCGTGATAAAGTTCTCCAT
TCTGATGAAGATGCAGATATAGATGAAAATGAAGAAGATATTGGAAATCATTCAATGATAGATGAGGAAATTGATGAACC
AACACAAGAATTCCCAATTCAAAATTATCGTAGAAGTCGAAATAAAAAATAA

Upstream 100 bases:

>100_bases
AATATGGGGAAGCAACAAAAATGAGTCGAGAATTTTTGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGAT
GTTCTTAGAAAAATCTAAAT

Downstream 100 bases:

>100_bases
GAAAAACCTCTAATTTTAGAGGTTTTTTGATATCTAAAAATGCCTGTTGTCATTTATTATTTATATTGCGATTAATAAAA
ATAATGTATGCGAAAATAAC

Product: polysacharide biosynthesis protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVH
NQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIP
FGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFP
YNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMA
LGFTHRGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLH
SDEDADIDENEEDIGNHSMIDEEIDEPTQEFPIQNYRRSRNKK

Sequences:

>Translated_443_residues
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVH
NQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIP
FGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFP
YNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMA
LGFTHRGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLH
SDEDADIDENEEDIGNHSMIDEEIDEPTQEFPIQNYRRSRNKK
>Mature_443_residues
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVH
NQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIP
FGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFP
YNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMA
LGFTHRGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLH
SDEDADIDENEEDIGNHSMIDEEIDEPTQEFPIQNYRRSRNKK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=323, Percent_Identity=26.9349845201238, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 48884; Mature: 48884

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHCCHHHHHHCCCCC
>Mature Secondary Structure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HHHHCCCHHHCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]