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The map label for this gene is yrfE

Identifier: 15673684

GI number: 15673684

Start: 1758958

End: 1760361

Strand: Reverse

Name: yrfE

Synonym: L142310

Alternate gene names: 15673684

Gene position: 1760361-1758958 (Counterclockwise)

Preceding gene: 15673685

Following gene: 15673683

Centisome position: 74.42

GC content: 35.68

Gene sequence:

>1404_bases
ATGACAATGAATGAAAAAAAGTATAAACGCTTAGAATATTTGAGACATAACATCAATTATCTCACAATCCGAGAGCGTCA
AGAGTACTATGACTTACTCAATGAACTAAAAAAAGCTGGAAATCAATCTGAACCCGAAGAATTCGAGGAATTTGAAGAAT
ACGTCGAGCCAGAATATGAATATTCCGATTATGAACCAGAAAGCTTTCAAAAAAATACTTCCTCTTCTAATGGTAGAAAT
GCTAGTCGAAGAAATACGCGAGAAAGTTTTTCAAATCAAGAAAACAACAGAAATAAACCATCAAAAAAAGAAAGTAAATC
TTCTAAAAAAGCTAAATCTGGCAAGAAGAAAAAACGTCACTGGTTAAGAACAATATTAACAATTATTGTTGTGATCATTG
CGGTCATGATTGGTTTCTTTGTTTATGGATATCAAAGGGGCGTTAAACATGAGGGAAGCGTCGCTAAACAAGAAAAGTTC
ACAAGTTTAAAAAATTCGGACGGTTCTGTAAATATTCTTTTGTTAGGAGCAGACCAAAGACCATGGCAATCATCAGGTGT
TGCTCATACCGATACTATTATGGTTTTACATGTCAATGGCAAGAACCATCAAACACAAATCGTGAGCTTTATGCGTGATA
CCCTTGTCAATATTCCTGATGTCGGCTCAAGTGATACTCCAGACTCAAAAATAAATTCTGCCTTTACAATTGGAGAACAA
TACAATAAACAGGGTGTGAATTTGATGAGTGAGACACTGAAAAATAACTTTGGCATTAATTGTCAATATTATGCAGTCGT
CGATTTTTCAAGTTTTGCAACGATTATTGATTCTTTGTTCCCAACTGGCCTAAAAATTGATGCAAAATTTTCGACTGTGA
ATGGTGAGAATCTTTCTGCCGTACCTGTTCCCGATGATTTAGCTGCAACAGAAGGAAAAGTTTCAAGTGACAAAGACTTG
ACAGCTGAAGAAGCAGCCGCTTTAGGTTATCCTGATGGTGGTGGAACATTTATGATGATTAAACCAGGAACTCAAAAAAT
GGATGGACGAATGCTCTTGAATTATGCCCGATTCCGTCATGATGATGAGGGAGATTATGGACGAGTAAAACGTCAACAAC
AAGTTTTAGAAACAGTAATGTCTAAAATGAAAAATCCACTCTCATTGTTTACTGCTTCAAGTGCGTTGGGAACAACAAGA
GCAGTTACAATGACGAATATTCCAAATTCATTTTTCTTAACTAAAGGAATTACAGCTCTTCTGGATATGAAAAATGGTAT
AAAATCAACAACAATTCCAGCTAACAATGACTGGGAGAATGCCTATGATATGTATGGAGGTCTAGGACTTTCAATTGATA
TGACAAAATACAAAGCGAAAGCCCAAGAACTTCTTGGTCAATAA

Upstream 100 bases:

>100_bases
ACAAAGCTAAAGAACTCATGTAAATGAGTTCTTTTTAATTATTAGATAGTCTAAAGATTGGTAAGATTTTGCAGGAATTA
TCAAACTTTGATATAATAAT

Downstream 100 bases:

>100_bases
AGAGAAAATTACTAACAGTTTTGTTAGTAATTTTTAATTTTAAATATTCATATGAAAAAAATGATGACAATTTTTTTCTT
TAGTTATTGATTAATGGCTT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTMNEKKYKRLEYLRHNINYLTIRERQEYYDLLNELKKAGNQSEPEEFEEFEEYVEPEYEYSDYEPESFQKNTSSSNGRN
ASRRNTRESFSNQENNRNKPSKKESKSSKKAKSGKKKKRHWLRTILTIIVVIIAVMIGFFVYGYQRGVKHEGSVAKQEKF
TSLKNSDGSVNILLLGADQRPWQSSGVAHTDTIMVLHVNGKNHQTQIVSFMRDTLVNIPDVGSSDTPDSKINSAFTIGEQ
YNKQGVNLMSETLKNNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGENLSAVPVPDDLAATEGKVSSDKDL
TAEEAAALGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLSLFTASSALGTTR
AVTMTNIPNSFFLTKGITALLDMKNGIKSTTIPANNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ

Sequences:

>Translated_467_residues
MTMNEKKYKRLEYLRHNINYLTIRERQEYYDLLNELKKAGNQSEPEEFEEFEEYVEPEYEYSDYEPESFQKNTSSSNGRN
ASRRNTRESFSNQENNRNKPSKKESKSSKKAKSGKKKKRHWLRTILTIIVVIIAVMIGFFVYGYQRGVKHEGSVAKQEKF
TSLKNSDGSVNILLLGADQRPWQSSGVAHTDTIMVLHVNGKNHQTQIVSFMRDTLVNIPDVGSSDTPDSKINSAFTIGEQ
YNKQGVNLMSETLKNNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGENLSAVPVPDDLAATEGKVSSDKDL
TAEEAAALGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLSLFTASSALGTTR
AVTMTNIPNSFFLTKGITALLDMKNGIKSTTIPANNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
>Mature_466_residues
TMNEKKYKRLEYLRHNINYLTIRERQEYYDLLNELKKAGNQSEPEEFEEFEEYVEPEYEYSDYEPESFQKNTSSSNGRNA
SRRNTRESFSNQENNRNKPSKKESKSSKKAKSGKKKKRHWLRTILTIIVVIIAVMIGFFVYGYQRGVKHEGSVAKQEKFT
SLKNSDGSVNILLLGADQRPWQSSGVAHTDTIMVLHVNGKNHQTQIVSFMRDTLVNIPDVGSSDTPDSKINSAFTIGEQY
NKQGVNLMSETLKNNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGENLSAVPVPDDLAATEGKVSSDKDLT
AEEAAALGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLSLFTASSALGTTRA
VTMTNIPNSFFLTKGITALLDMKNGIKSTTIPANNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 52505; Mature: 52374

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNEKKYKRLEYLRHNINYLTIRERQEYYDLLNELKKAGNQSEPEEFEEFEEYVEPEYE
CCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
YSDYEPESFQKNTSSSNGRNASRRNTRESFSNQENNRNKPSKKESKSSKKAKSGKKKKRH
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
WLRTILTIIVVIIAVMIGFFVYGYQRGVKHEGSVAKQEKFTSLKNSDGSVNILLLGADQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCC
PWQSSGVAHTDTIMVLHVNGKNHQTQIVSFMRDTLVNIPDVGSSDTPDSKINSAFTIGEQ
CCCCCCCCEECEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEECHH
YNKQGVNLMSETLKNNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGENLSA
HCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
VPVPDDLAATEGKVSSDKDLTAEEAAALGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRH
CCCCCCHHCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCC
DDEGDYGRVKRQQQVLETVMSKMKNPLSLFTASSALGTTRAVTMTNIPNSFFLTKGITAL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
LDMKNGIKSTTIPANNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMNEKKYKRLEYLRHNINYLTIRERQEYYDLLNELKKAGNQSEPEEFEEFEEYVEPEYE
CCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
YSDYEPESFQKNTSSSNGRNASRRNTRESFSNQENNRNKPSKKESKSSKKAKSGKKKKRH
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
WLRTILTIIVVIIAVMIGFFVYGYQRGVKHEGSVAKQEKFTSLKNSDGSVNILLLGADQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCC
PWQSSGVAHTDTIMVLHVNGKNHQTQIVSFMRDTLVNIPDVGSSDTPDSKINSAFTIGEQ
CCCCCCCCEECEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEECHH
YNKQGVNLMSETLKNNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGENLSA
HCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEE
VPVPDDLAATEGKVSSDKDLTAEEAAALGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRH
CCCCCCHHCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCC
DDEGDYGRVKRQQQVLETVMSKMKNPLSLFTASSALGTTRAVTMTNIPNSFFLTKGITAL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
LDMKNGIKSTTIPANNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]