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The map label for this gene is dapB

Identifier: 15673543

GI number: 15673543

Start: 1604115

End: 1604897

Strand: Reverse

Name: dapB

Synonym: L0094

Alternate gene names: 15673543

Gene position: 1604897-1604115 (Counterclockwise)

Preceding gene: 15673544

Following gene: 15673542

Centisome position: 67.84

GC content: 39.21

Gene sequence:

>783_bases
ATGAAATTGAATAAAATTAAAGTGATTGTTGCTGGATTTCGTGGAAAAATGGGAGCTACTGCGGTACAAATGATTCTGAA
TGCTCAAAATTTTGAACTTATGGCTTTATTAGGAAAGAAAGAAGAAGTCTCAGAAGCGTTTGGAGTTCCTGTTTTTAGTC
GAAAAGAGGATTTGATTGGATTTGATGCTGACATTTGGCTAGATTTAACGGCTCCTGAAGCGGCTTATAAGAACACTCGT
TTTGCTTTAGAAAATGGCTTTAGACCAGTGGTTGGAACGACTGGGTTTACCGATGATGAAGTGGCAGATTTAATTAAATT
TTCTAGAGAAAAAGAATTGGGTGGTCTTATTGCACCAAATTTTGCCTTGGGTGCGGTTTTATTGATGCAATTTTCTAAGC
AGGCTGTTAAATATTTCCCAGATGTGGAAATTATTGAATTGCACCATGACGGGAAAAAAGATGCTCCTTCTGGAACTGCT
GTGAAGACAGCAGAATTGATGTCTGAGGAACGTTTGGCTCATCATCAAGGGGCAGTGGATGAAAAGGAAGCTTTAGCTGG
TGCTCGTGGTGCCGATCTTGAAGGAATGAGAATCCATTCGGTTCGTTTACCTGGTTTGGTGGCTCATCAAGAGGTTATTT
TTGGTTCAAAAGGTGAAGGGCTGACTTTACGTCATGATTCTTATGATCGTTCAAGTTTCATGACCGGTATTGCTTTGGGA
ATTCGTAAGGTAATGACGGTGTCTGAGTTAAAATATGGTTTGGAACATTTTTTGGATTTATAA

Upstream 100 bases:

>100_bases
AGCACGTTTTTACGTGTTTTTATCTAAAAACAAATATTCTGAATAATAAAAATAATAGCTACTTCTATAAAATACTAATT
TCTTTATAAATGAATGGGGG

Downstream 100 bases:

>100_bases
TATTTACTGACGAAATAGATTGTGACCGAATGATTAGTGAGGGATTTTATGAGTGAATTAGAGATTCGTAGATTAGAATT
AAGTGATGCAGAAGCTTTTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIGFDADIWLDLTAPEAAYKNTR
FALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMSEERLAHHQGAVDEKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL

Sequences:

>Translated_260_residues
MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIGFDADIWLDLTAPEAAYKNTR
FALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMSEERLAHHQGAVDEKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL
>Mature_260_residues
MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIGFDADIWLDLTAPEAAYKNTR
FALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMSEERLAHHQGAVDEKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=270, Percent_Identity=30.7407407407407, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_LACLA (Q9CFC0)

Other databases:

- EMBL:   AE005176
- PIR:   A86820
- RefSeq:   NP_267717.1
- ProteinModelPortal:   Q9CFC0
- SMR:   Q9CFC0
- GeneID:   1115221
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0094
- NMPDR:   fig|272623.1.peg.1603
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   LLAC272623:L0094-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28491; Mature: 28491

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIG
CCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCC
FDADIWLDLTAPEAAYKNTRFALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPN
CCCEEEEEECCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCH
FALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTAVKTAELMSEERLAHHQGAVD
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
HHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHH
IRKVMTVSELKYGLEHFLDL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLNKIKVIVAGFRGKMGATAVQMILNAQNFELMALLGKKEEVSEAFGVPVFSRKEDLIG
CCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCC
FDADIWLDLTAPEAAYKNTRFALENGFRPVVGTTGFTDDEVADLIKFSREKELGGLIAPN
CCCEEEEEECCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCH
FALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTAVKTAELMSEERLAHHQGAVD
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EKEALAGARGADLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
HHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHH
IRKVMTVSELKYGLEHFLDL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471